scholarly journals Detection of novel mutations in the gyrA gene of Staphylococcus aureus by nonradioisotopic single-strand conformation polymorphism analysis and direct DNA sequencing.

1994 ◽  
Vol 38 (3) ◽  
pp. 428-431 ◽  
Author(s):  
Y Tokue ◽  
K Sugano ◽  
D Saito ◽  
T Noda ◽  
H Ohkura ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Dna Sequencing ◽  
Single Strand Conformation Polymorphism ◽  
Single Strand ◽  
Polymorphism Analysis ◽  
Novel Mutations ◽  
Gyra Gene ◽  
Direct Dna Sequencing ◽  
Conformation Polymorphism Analysis ◽  
Conformation Polymorphism

scholarly journals gyrA Polymorphism in Campylobacter jejuni: Detection of gyrA Mutations in 162 C. jejuni Isolates by Single-Strand Conformation Polymorphism and DNA Sequencing

2002 ◽  
Vol 46 (8) ◽  
pp. 2644-2647 ◽  
Author(s):  
Antti Hakanen ◽  
Jari Jalava ◽  
Pirkko Kotilainen ◽  
Hannele Jousimies-Somer ◽  
Anja Siitonen ◽  
...  
Keyword(s):  
Dna Sequencing ◽  
Point Mutation ◽  
Campylobacter Jejuni ◽  
Single Strand Conformation Polymorphism ◽  
Single Strand ◽  
Quinolone Resistance ◽  
Polymorphism Analysis ◽  
Conformation Polymorphism Analysis ◽  
Conformation Polymorphism

ABSTRACT Mutations in the quinolone resistance-determining region of the gyrA gene from 138 ciprofloxacin-resistant (MIC, ≥4 μg/ml) and 24 ciprofloxacin-susceptible (MIC, ≤1 μg/ml) clinical Campylobacter jejuni isolates were subjected to single-strand conformation polymorphism analysis and sequencing. All of the isolates could be assigned to three genotypic clusters based on silent mutations. All resistant isolates had a point mutation at codon 86.

Sign in / Sign up

Export Citation Format

Share Document