scholarly journals Penetration of aztreonam into cerebrospinal fluid and brain of noninfected rabbits and rabbits with experimental meningitis caused by Pseudomonas aeruginosa.

1986 ◽  
Vol 30 (5) ◽  
pp. 701-704 ◽  
Author(s):  
L J Strausbaugh ◽  
C R Bodem ◽  
P R Laun
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Cerebrospinal Fluid

Filamented Pseudomonas aeruginosa anda Markedly High Level of Endotoxin in Cerebrospinal Fluid

2000 ◽  
Vol 41 (1) ◽  
pp. 114-115
Author(s):  
C. Kawano ◽  
K. Muroi ◽  
M. Yozhizawa ◽  
T. Kirikae ◽  
K. Ozawa
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Cerebrospinal Fluid ◽  
High Level

scholarly journals Plasmid Carrying blaCTX-M-2 and blaGES-1 in Extensively Drug-Resistant Pseudomonas aeruginosa from Cerebrospinal Fluid

2019 ◽  
Vol 63 (7) ◽  
Author(s):  
Anelise Stella Ballaben ◽  
Renata Galetti ◽  
Leonardo Neves Andrade ◽  
Joseane Cristina Ferreira ◽  
Doroti de Oliveira Garcia ◽  
...  
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Cerebrospinal Fluid ◽  
Drug Resistant ◽  
Extensively Drug Resistant

A Report on Pseudomonas aeruginosa from Green Cerebrospinal Fluid- Meningitis

2021 ◽  
pp. 79-85
Author(s):  
R. Bawane ◽  
K. Ingole ◽  
M. Bhise ◽  
S. Mundhada
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Cerebrospinal Fluid

How long should cerebrospinal fluid cultures be held to detect shunt infections?

2009 ◽  
Vol 4 (2) ◽  
pp. 184-189 ◽  
Author(s):  
Atman Desai ◽  
Stuart Scott Lollis ◽  
Symeon Missios ◽  
Tarek Radwan ◽  
Deborah E. Zuaro ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Cerebrospinal Fluid ◽  
Antibiotic Treatment ◽  
Shunt Infection ◽  
Significant Difference ◽  
Few Data ◽  
Prior Antibiotic Treatment ◽  
Shunt Infections ◽  
Observation Period

Object Infections of CSF hardware may be indolent, and some patients have received antibiotic treatment for various reasons before CSF is obtained to check for a shunt infection. At present, there are few data in the literature to guide the decision as to how long to hold CSF specimens when attempting to diagnose hardware infections, and institutions vary in the duration at which cultures are considered “final.” Methods The authors reviewed the microbiology data from CSF specimens obtained from shunts, ventriculostomies, reservoirs, and lumbar drains at their institution over a 36-month period to discover how long after collection cultures became positive. The authors also sought to discover whether this time was affected by prior treatment with antibiotics. Results Of 158 positive CSF specimens obtained from hardware, the time to recovery ranged between 1–10 days, with a mean of 3.02 days (SD 2.37 days, 95% CI 2.66–3.38 days). One hundred and twenty-seven positive specimens were associated with clinical infections, and ~ 25% of these grew organisms after > 3 days, with some as long as 10 days after specimens were obtained. The most common organisms grown from individual patients were coagulase-negative Staphylococcus spp (34 cultures), Propionibacterium spp (21), Bacillus spp (6), Pseudomonas aeruginosa (4), and Staphylococcus aureus (4 cultures). Mean and maximum days to recovery were different across species, with S. aureus showing the shortest and Propionibacterium spp showing the longest incubation times. There appeared to be no significant difference in the time to recovery between specimens obtained in patients who had received prior antibiotic treatment versus those who had not. Conclusions A substantial number of positive CSF specimens obtained in patients with clinical infections grew bacteria after > 3 days, with some requiring as long as 10 days. Thus, a routine 10-day observation period for CSF specimens can be justified.

scholarly journals Plasma and Cerebrospinal Fluid Therapeutic Drug Monitoring of Ceftolozane and Tazobactam During Treatment of Multidrug-Resistant Pseudomonas aeruginosa Meningitis

2020 ◽  
Vol 7 (12) ◽  
Author(s):  
Erin K McCreary ◽  
Karin E Byers ◽  
Carolyn Fernandes ◽  
Ellen G Kline ◽  
David P Nicolau ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Pseudomonas Aeruginosa ◽  
Cerebrospinal Fluid ◽  
Therapeutic Drug Monitoring ◽  
Drug Monitoring ◽  
Cerebral Spinal Fluid ◽  
Multidrug Resistant ◽  
Therapeutic Drug ◽  
Central Nervous System Infections ◽  
Case Basis

Abstract We report a case of multidrug-resistant Pseudomonas aeruginosa meningitis treated with ceftolozane-tazobactam with concomitant therapeutic drug monitoring of plasma and cerebral spinal fluid. The data suggest that ceftolozane-tazobactam may be an option for select central nervous system infections; however, treatment decisions should be interpreted on a case-by-case basis.

Pharmacokinetics of Cefsulodin in Rat Cerebrospinal Fluid during Experimental Pseudomonas aeruginosa Meningitis

Chemotherapy ◽  
1989 ◽  
Vol 35 (4) ◽  
pp. 237-241 ◽  
Author(s):  
A. Meulemans ◽  
P. Vicart ◽  
B. Pangon ◽  
J. Mohler ◽  
L. Bocquet ◽  
...  
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Cerebrospinal Fluid
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