scholarly journals Antimicrobial Susceptibility Testing of Pneumococci: Determination of Kirby-Bauer Breakpoints for Penicillin G, Erythromycin, Clindamycin, Tetracycline, Chloramphenicol, and Rifampin

1979 ◽  
Vol 16 (2) ◽  
pp. 190-197 ◽  
Author(s):  
M. R. Jacobs ◽  
Y. Mithal ◽  
R. M. Robins-Browne ◽  
M. N. Gaspar ◽  
H. J. Koornhof
Keyword(s):  
Antimicrobial Susceptibility ◽  
Susceptibility Testing ◽  
Antimicrobial Susceptibility Testing ◽  
Penicillin G

scholarly journals Rapid Antimicrobial Susceptibility Testing Using Forward Laser Light Scatter Technology

2016 ◽  
Vol 54 (11) ◽  
pp. 2701-2706 ◽  
Author(s):  
Randall T. Hayden ◽  
Lani K. Clinton ◽  
Carolyn Hewitt ◽  
Terri Koyamatsu ◽  
Yilun Sun ◽  
...  
Keyword(s):  
Antimicrobial Susceptibility ◽  
Clinical Decision Making ◽  
Susceptibility Testing ◽  
Laser Light ◽  
Accurate Determination ◽  
Antimicrobial Susceptibility Testing ◽  
Limiting Factor ◽  
Light Scatter ◽  
Content Type

The delayed reporting of antimicrobial susceptibility testing remains a limiting factor in clinical decision-making in the treatment of bacterial infection. This study evaluates the use of forward laser light scatter (FLLS) to measure bacterial growth for the early determination of antimicrobial susceptibility. Three isolates each (two clinical isolates and one reference strain) ofStaphylococcus aureus,Escherichia coli, andPseudomonas aeruginosawere tested in triplicate using two commercial antimicrobial testing systems, the Vitek2 and the MicroScan MIC panel, to challenge the BacterioScan FLLS. The BacterioScan FLLS showed a high degree of categorical concordance with the commercial methods. Pairwise comparison with each commercial system serving as a reference standard showed 88.9% agreement with MicroScan (two minor errors) and 72.2% agreement with Vitek (five minor errors). FLLS using the BacterioScan system shows promise as a novel method for the rapid and accurate determination of antimicrobial susceptibility.

scholarly journals Antimicrobial Susceptibility Patterns in Neisseria gonorrhoeae Isolated from South African Pregnant Women

2021 ◽  
Vol 2021 ◽  
pp. 1-6
Author(s):  
Glynis Oree ◽  
Meleshni Naicker ◽  
Hopolang Clifford Maise ◽  
Partson Tinarwo ◽  
Nathlee Samantha Abbai
Keyword(s):  
Neisseria Gonorrhoeae ◽  
Pregnant Women ◽  
Antimicrobial Susceptibility ◽  
Susceptibility Testing ◽  
Treatment Guidelines ◽  
Antimicrobial Susceptibility Testing ◽  
Penicillin G ◽  
Transmitted Infection ◽  
Adverse Pregnancy ◽  
Susceptibility Patterns

Background. Neisseria gonorrhoeae, a sexually transmitted infection, is associated with adverse pregnancy and neonatal outcomes. Emerging resistance towards various antibiotics has been observed globally. However, there is a lack of data on antimicrobial susceptibility patterns in N. gonorrhoeae isolated from pregnant women in our setting. This study fills in this gap in the literature. Methods. The study population included pregnant women, recruited from the antenatal clinic of the King Edward VIII hospital (KEH) in Durban. Endocervical swabs were obtained from 307 women. The swab was placed in Amies Charcoal media for culture assessments. Pure isolates of N. gonorrhoeae were subjected to antimicrobial susceptibility testing using the Etest™ method. The MIC values were assessed in accordance with the European Committee on Antimicrobial Susceptibility Testing (EUCAST, 2019) breakpoints. Results. The prevalence of N. gonorrhoeae by culture was 1.9%. High MIC values to penicillin G (12-64 mg/L) indicating a resistant phenotype were observed for all isolates tested, with 50% of the isolates displaying complete resistance. Isolates with intermediate (1 mg/L) and resistance (1.9-32 mg/L) profiles to tetracycline were observed. Resistance to ciprofloxacin (1.16-3 mg/L) was also observed. Isolates displayed either dual or triple resistance to penicillin G, tetracycline, or ciprofloxacin. All isolates showed susceptibility to spectinomycin (>64 mg/L), azithromycin (1 mg/L), ceftriaxone (>0.125 mg/L), and cefixime (>0.125 mg/L). Conclusion. Despite lack of resistance to ceftriaxone and azithromycin, continuous surveillance for emerging patterns of resistance to these antibiotics is needed since they form part of the treatment guidelines.

scholarly journals Antimicrobial Susceptibility of Propionibacterium acnes Isolates from Shoulder Surgery

2013 ◽  
Vol 57 (7) ◽  
pp. 3424-3426 ◽  
Author(s):  
John K. Crane ◽  
Donald W. Hohman ◽  
Scott R. Nodzo ◽  
Thomas R. Duquin
Keyword(s):  
Antimicrobial Susceptibility ◽  
Susceptibility Testing ◽  
Propionibacterium Acnes ◽  
Shoulder Surgery ◽  
Antimicrobial Susceptibility Testing ◽  
Penicillin G ◽  
Microbiology Laboratory ◽  
Content Type ◽  
Orthopedic Surgeons

ABSTRACTOrthopedic surgeons at our institution have noticed an increase in the number of infections due toPropionibacterium acnes, especially following operations on the shoulder. We collectedP. acnesisolates from our hospital microbiology laboratory for 1 year and performed antimicrobial susceptibility testing on 28 strains from the shoulder. Antibiotics with the lowest MIC values againstP. acnes(MIC50and MIC90) included penicillin G (0.006, 0.125), cephalothin (0.047 and 0.094), and ceftriaxone (0.016, 0.045), while others also showed activity. Strains resistant to clindamycin were noted.

scholarly journals Antimicrobial Susceptibility Pattern of Bacterial Isolates from Wound Infection

2018 ◽  
Vol 26 ◽  
pp. 61-66
Author(s):  
S Gul Nahar ◽  
M Bulbul Hasan ◽  
M Nawshad Ali ◽  
Mst Rokeya Khatun ◽  
K Khanam
Keyword(s):  
Wound Infection ◽  
Antimicrobial Susceptibility ◽  
Susceptibility Testing ◽  
Antimicrobial Susceptibility Testing ◽  
Penicillin G ◽  
Bacterial Isolates ◽  
Susceptibility Pattern ◽  
Coagulase Negative Staphylococci ◽  
Antimicrobial Susceptibility Pattern ◽  
Gram Positive Bacteria

Objective: The present study was done to see the antimicrobial susceptibility pattern of bacterial isolates from wound infection.Methods: Wound swabs collected from 150 patients of wound infection were cultured and microbial isolates identified using standard methods. Antimicrobial susceptibility testing was done on bacterial isolates by Modified Kirby Bauer method.Results: Of the 150 swabs 131 (87.4%) were culture positive for bacterial pathogens, while 19 (12.6%) were bacteriologically sterile showing an isolation rate of 87.4%. The predominant bacteria isolated from the infected wounds were Staphylococcus aureus 47 (32.4%) followed by Escherichia coli 29 (20%), Proteus species 23 (16%), Coagulase negative Staphylococci 21 (14.5%), Klebsiella pneumoniae 14 (10%) and Pseudomonas aeruginosa 11 (8%).In case of gram positive bacteria- rate of isolates resistant to ampicillin was 94%, followed by penicillin G, 86.8%, Tetracycline, 51.5%. In case of gram negative bacteria- rate of isolates resistant to ampicillin was 96%, followed by cephalothin, 92.4%, Tetracycline, 74%.Conclusion: In antimicrobial susceptibility testing ampicillin, penicillin, cephalothin and tetracycline were the least effective. Gentamicin, norfloxacin, ciprofloxacin, vancomycin and amikacin were the most effective antibiotics.TAJ 2013; 26: 61-66

Pretreatment antimicrobial susceptibility testing is cost saving in the eradication of

2003 ◽  
Vol 1 (4) ◽  
pp. 273-278 ◽  
Author(s):  
Marco Romano ◽  
Riccardo Marmo ◽  
Antonio Cuomo ◽  
Teresa De Simone ◽  
Caterina Mucherino ◽  
...  
Keyword(s):  
Cost Saving ◽  
Antimicrobial Susceptibility ◽  
Susceptibility Testing ◽  
Antimicrobial Susceptibility Testing

NGHIÊN CỨU SỰ NHẠY CẢM VỚI KHÁNG SINH CỦA MỘT SỐ CHỦNG VI KHUẨN GÂY VIÊM ĐƯỜNG HÔ HẤP CẤP Ở TRẺ EM DƯỚI 6 TUỔI TẠI BỆNH VIỆN NHI THANH HÓA 2009 - 2014

2020 ◽  
Vol 4 (3) ◽  
Author(s):  
Hoai Do Ngoc
Keyword(s):  
Antimicrobial Susceptibility ◽  
Susceptibility Testing ◽  
Antimicrobial Susceptibility Testing ◽  
High Rate ◽  
Isolation Rate

From 43.574 fluid nasopharynx speciments of  the chidren inpatient under six we isolated total 21.769 types bacteria with isolation rate : 49.95%. In which the highest isolation rate for H. influenza, S. pneumoniae and M. catarrhalis were 13,94%; 7,11%; 1,43% respectively. Antimicrobial susceptibility testing shown all the types of  for H. influenza, S. pneumoniae and M. catarrhalis good susses to Fosphomycine, S. pneumoniae and M. catarrhalis good susses to Imipenem, H. influenza good susses to Azithromycine, S. pneumoniae good susses to Penicilline and Piperacilline, M. catarrhalis good susses to Tobramycine and Ofloxacine. All of  H. influenza, S. pneumoniae and M. catarrhalis were reported resistance to Tri/Sulpha, Chloramphenicol, Erythromycine in high rate.

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