scholarly journals Outbreak of Multiply Drug-Resistant Proteus mirabilis Originating in a Surgical Intensive Care Unit: In Vitro Susceptibility Pattern

1978 ◽  
Vol 13 (2) ◽  
pp. 177-179 ◽  
Author(s):  
T. T. Yoshikawa ◽  
S. A. Shibata ◽  
A. W. Chow ◽  
L. B. Guze
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Proteus Mirabilis ◽  
Surgical Intensive Care Unit ◽  
Drug Resistant ◽  
Susceptibility Pattern ◽  
Surgical Intensive Care ◽  
In Vitro Susceptibility

Serratia marcescans Contamination of Antiseptic Soap Containing Triclosan: Implications for Nosocomial Infection

1984 ◽  
Vol 5 (9) ◽  
pp. 427-430 ◽  
Author(s):  
M. Anita Barry ◽  
Donald E. Craven ◽  
Theresa A. Goularte ◽  
Deborah A. Lichtenberg
Keyword(s):  
Intensive Care Unit ◽  
Pseudomonas Aeruginosa ◽  
Intensive Care ◽  
Nosocomial Infection ◽  
Surgical Intensive Care Unit ◽  
Minimal Bactericidal Concentration ◽  
Surgical Intensive Care ◽  
Time Kill ◽  
The Impact

Abstract During a recent investigation in our surgical intensive care unit, we found that several bottles of the antiseptic handwashing soap, OR Scrub®, were contaminated with Serratia marcescens. OR Scrub® contains 1% triclosan, lanolin, and detergents. The antimicrobial efficacy of OR Scrub® was examined in vitro using serial two-fold dilutions of soap inoculated with various concentrations of different nosocomial pathogens. The minimal bactericidal concentration (MBC) of OR Scrub® against Pseudomonas aeruginosa and several strains of S. marcescens was ≤1:2 By comparison, a non-antiseptic soap from the same manufacturer (Wash®) and 4% chlorhexidine (Hibiclens®) had MBCs for all strains tested of at least 1:64. Time-kill curves confirmed the findings of the initial experiments.This is the first report of extrinsic contamination of antiseptic soap containing triclosan. No infections could be attributed to the contaminated soap, but sporadic outbreaks of Serratia have occurred in the intensive care unit with no identifiable source. Although there have been few studies on the impact of antiseptic soap in reducing nosocomial infection, we question whether a soap with the limitations of OR Scrub® should be used in intensive care units or operating rooms.

scholarly journals An outbreak of infection due to metallo-ß-lactamase-producing Proteus mirabilis in the surgical intensive care unit

2011 ◽  
Vol 42 (2) ◽  
pp. 75-79
Author(s):  
Veljko Mirović ◽  
Biljana Carević ◽  
Srđan Stepanović ◽  
Zorica Lepšanović
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Proteus Mirabilis ◽  
Surgical Intensive Care Unit ◽  
Surgical Intensive Care
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