scholarly journals Universal In Vitro Antifungal Resistance of Genetic Clades of the Fusarium solani Species Complex

2007 ◽  
Vol 51 (4) ◽  
pp. 1500-1503 ◽  
Author(s):  
Mónica Azor ◽  
Josepa Gené ◽  
Josep Cano ◽  
Josep Guarro
Keyword(s):  
Sequence Analysis ◽  
Amphotericin B ◽  
Fusarium Solani ◽  
Species Complex ◽  
Active Drug ◽  
Antifungal Resistance ◽  
Antifungal Drugs ◽  
Multilocus Sequence Analysis ◽  
Fusarium Solani Species Complex

ABSTRACT Eleven antifungal drugs were tested against representative isolates of the four phylogenetic clades of the Fusarium solani species complex obtained in a multilocus sequence analysis. They all showed very poor activity, with no differences among the clades. Amphotericin B was the most active drug.

scholarly journals Rifampin Enhances the Activity of Amphotericin B against Fusarium solani Species Complex and Aspergillus flavus Species Complex Isolates from Keratitis Patients

2017 ◽  
Vol 61 (4) ◽  
Author(s):  
Yi He ◽  
Lutan Zhou ◽  
Chuanwen Gao ◽  
Lei Han ◽  
Yan Xu
Keyword(s):  
Amphotericin B ◽  
Aspergillus Flavus ◽  
Fusarium Solani ◽  
Species Complex ◽  
Content Type ◽  
Fusarium Solani Species Complex ◽  
Fungal Isolates

ABSTRACT The in vitro activities of amphotericin B in combination with rifampin were assessed against 95 ocular fungal isolates. The interactions between amphotericin B and rifampin at 4, 8, 16, and 32 μg/ml were synergistic for 11.8%, 51.0%, 90.2%, and 94.1%, respectively, of Fusarium solani species complex isolates and for 13.6%, 45.5%, 93.2%, and 95.5%, respectively, of Aspergillus flavus species complex isolates. Antagonism was never observed for the amphotericin B-rifampin combinations.

scholarly journals In Vitro and In Vivo Experimental Activities of Antifungal Agents against Fusarium solani

1999 ◽  
Vol 43 (5) ◽  
pp. 1256-1257 ◽  
Author(s):  
J. Guarro ◽  
I. Pujol ◽  
E. Mayayo
Keyword(s):  
Drug Therapy ◽  
Amphotericin B ◽  
Fusarium Solani ◽  
Antifungal Agents ◽  
Antifungal Drugs ◽  
Infection Model ◽  
Disseminated Infection

ABSTRACT In the treatment of disseminated Fusarium infections, amphotericin B either alone or in combination with flucytosine and rifampin is the drug therapy most frequently used. The efficacy of these antifungal drugs was evaluated in a murine disseminated-infection model, with five strains of Fusarium solani. All the treatments were clearly ineffective.

scholarly journals Natamycin and Azithromycin Are Synergistic In Vitro against Ocular Pathogenic Aspergillus flavus Species Complex and Fusarium solani Species Complex Isolates

2018 ◽  
Vol 62 (7) ◽  
pp. e00077-18 ◽  
Author(s):  
Haoyi Guo ◽  
Lutan Zhou ◽  
Yi He ◽  
Chuanwen Gao ◽  
Lei Han ◽  
...  
Keyword(s):  
Aspergillus Flavus ◽  
Fusarium Solani ◽  
Species Complex ◽  
Content Type ◽  
Fusarium Solani Species Complex ◽  
Synergistic Interactions ◽  
Fungal Isolates

ABSTRACT The interaction of natamycin-azithromycin combination against 60 ocular fungal isolates was tested in vitro. The combination produced 100% synergistic interactions when natamycin was added to azithromycin 20, 40, and 50 μg/ml against Aspergillus flavus species complex (AFSC) isolates and to azithromycin 50 μg/ml against Fusarium solani species complex isolates. Addition of 50 μg/ml azithromycin enhanced natamycin's effect against AFSC isolates by reducing natamycin MIC90 from 64 to 0.031 μg/ml. No antagonism was observed.

scholarly journals In VitroActivities of Nine Antifungal Drugs against 81 Phialophora and Cyphellophora Isolates

2012 ◽  
Vol 56 (11) ◽  
pp. 6044-6047 ◽  
Author(s):  
Peiying Feng ◽  
M. Javad Najafzadeh ◽  
Jiufeng Sun ◽  
Sarah Ahmed ◽  
Liyan Xi ◽  
...  
Keyword(s):  
Amphotericin B ◽  
Antifungal Drugs ◽  
Content Type

ABSTRACTCyphellophora guyanensis(n= 15), otherCyphellophoraspecies (n= 11),Phialophora europaea(n= 43), and otherPhialophoraspecies (n= 12) were testedin vitroagainst nine antifungal drugs. The MIC90s across all of the strains (n= 81) were, in increasing order, as follows: posaconazole, 0.063 μg/ml; itraconazole, 0.5 μg/ml; voriconazole, 1 μg/ml; micafungin, 1 μg/ml; terbinafine, 2 μg/ml; isavuconazole, 4 μg/ml; caspofungin, 4 μg/ml; fluconazole, 8 μg/ml; amphotericin B, 16 μg/ml.

scholarly journals Members of the Fusarium solani species complex that cause infections in both humans and plants are common in the environment

2006 ◽  
Vol 142 (5) ◽  
pp. 897
Author(s):  
N. Zhang ◽  
K. O’Donnell ◽  
D.A. Sutton ◽  
F.A. Naim ◽  
R.C. Summerbell ◽  
...  
Keyword(s):  
Fusarium Solani ◽  
Species Complex ◽  
Fusarium Solani Species Complex
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