A probable case of congenital syphilis from pre-Columbian Austria

2015 ◽  
Vol 72 (4) ◽  
pp. 451-472 ◽  
Author(s):  
Johanna Sophia Gaul ◽  
Karl Grossschmidt ◽  
Christian Gusenbauer ◽  
Fabian Kanz
Keyword(s):  
Congenital Syphilis ◽  
Probable Case

scholarly journals Manifestações orais da sífilis: revisão sistematizada de literatura

2019 ◽  
Vol 8 (8) ◽  
Author(s):  
Erison Santana Santos ◽  
Jamile de Oliveira Sá ◽  
Rachel Lamarck
Keyword(s):  
Congenital Syphilis ◽  
Health Sector ◽  
Secondary Syphilis ◽  
World Health ◽  
Oral Manifestations ◽  
Oral Diseases ◽  
Probable Case ◽  
Sexually Transmitted ◽  
Global Epidemiology ◽  
Head Neck

A sífilis é uma infecção bacteriana exclusiva de seres humanos que é transmitida principalmente através de relações sexuais sem o uso de preservativos. Embora seja mais comum em regiões genitais, pode manifestar sinais e sintomas na cavidade oral e mimetizar lesões potencialmente malignas e, dependendo do seu estágio, pode levar ao óbito. O objetivo desse estudo foi realizar uma revisão de literatura a fim de conhecer as principais manifestações orais da sífilis. Foi realizado um levantamento bibliográfico na base de dados PubMed e SciELO. A busca foi realizada durante o mês de agosto e setembro de 2018. No PubMed, foram utilizados os termos “syphilis oral”, “manifestations of syphilis”, “syphilis in oral cavity”, “syphilis in buccal cavity”, “syphilis in mouth”. Na SciELO, foram usadas os descritores: “oral manifestations of syphilis”, “manifestações orais AND sífilis”. As manifestações orais da sífilis embora sejam raras, são importantes para o cirurgiã-dentista diagnosticar a infecção em estágios menos agressivos da doença. Pode manifestar-se de diversas formas, dependendo do período de evolução da infecção. Sua incidência vem aumentando devido às mudanças de hábitos na população, principalmente nos grupos de risco. Sendo assim, conhecer as principais manifestações orais da sífilis é importante para intervir em estágios menos avançados, visto que é uma infecção que pode se disseminar rapidamente e levar o paciente a óbito se não tratada.  Descritores: Sífilis; Manifestações Bucais; Cancro; Treponema pallidum.ReferênciasLeuci S, Martina S, Adamo D, Ruoppo E, Santarelli A, Sorrentino R et al. Oral Syphilis: a retrospective analysis of 12 cases and a review of literature. Oral diseases. 2013;19(8):738-46.Leão JC, Gueiros LAM, Porter SR. Oral manifestations of syphilis. Clinics. 2006;61(2):161-66.Bruce AJ, Rogers RS 3rd. Oral manifestations of sexually transmitted diseases. Clin Dermatol. 2004;22(6):520-27.Neville BW, Damm DD, Allan CM, Chi AC. Patologia Oral e Maxilofacial. 4.ed. Elsevier: Rio de Janeiro; 2016.Kojima N, Klausner JD. An update on the global epidemiology of syphilis. Curr  Epidemiol Rep. 2018;5(1):24-38.World Health Organization. Global health sector strategy on sexually transmitted infections 2016-2021. 2016. The WHO's strategy for STI treatment.Carbone PN, Capra GG, Nelson BL. Oral Secondary Syphilis. Head Neck Pathol. 2016; 10(2):206-8.Dickenson AJ, Currie WJ, Avery BS. Screening for syphilis in patients with carcinoma of the tongue. Br J Oral Maxillofac Surg. 1995;33(5):319-20.Ficarra G, Carlos R. Syphilis: the renaissance of a old disease with oral implications. Head Neck Pathol. 2009;3(3):195-206.Gaul JS, Grossschimdt K, Gusenbauer C, Kanz F.  A probable case of congenital syphilis from pre-Columbian Austria. Anthropol Anz. 2015; 72(4):451-72.Jones L, Ong ELC, Okpokman A, Sloan P, Macleod I, Staines KS. Three cases of oral syphilis - an overview. Br Dental J. 2012; 212(10):477-80.Little JW. Syphilis: a update. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2005;100(1):3-9.Minicucci EM, Vieira RA, Oliveira DT, Marques SA. Oral manifestations of secondary syphilis in the elderly – a timely reminder for dentists. Aust Dent J. 2013;58(3):368-70.Paulo LF, Servato JP, Oliveira MT, Duriguetto AF Jr, Zanetta-Barbosa D. Oral manifestations of oral syphilis. Int J Infect Dis. 2015;35:40-2.Scott CM, Flint SR. Oral syphilis—re-emergence of an old disease with oral manifestations. Int J Oral Maxillofac Surg. 2005;34(1):58-63.Siqueira CS, Saturno JL, Sousa SCO, Silveira FR. Diagnostic approaches in unsuspected oral lesions of syphilis.   Int J Oral Maxillofac Surg. 2014; 43(12):1436-40.Strieder LR, Léon JE, Carvalho YR, Kaminagakura E. Oral syphilis: report of three cases and characterization of the inflammatory cells. Annals of Diagnostic Pathology. 2015;19:76-80.

Dental stigmata and enamel thickness in a probable case of congenital syphilis from XVI century Croatia

2015 ◽  
Vol 60 (10) ◽  
pp. 1554-1564 ◽  
Author(s):  
Tomislav Lauc ◽  
Cinzia Fornai ◽  
Zrinka Premužić ◽  
Marin Vodanović ◽  
Gerhard W. Weber ◽  
...  
Keyword(s):  
Congenital Syphilis ◽  
Enamel Thickness ◽  
Probable Case

Congenital Syphilis Simulating Bone Neoplasm in 2-Month Old Infant – Case Report

2017 ◽  
Vol 2 (1) ◽  
Keyword(s):  
Case Report ◽  
Congenital Syphilis ◽  
Eosinophilic Granuloma ◽  
Osteolytic Lesion ◽  
Lower Limbs ◽  
Upper Body ◽  
Elective Cesarean Section ◽  
Distal Fibula ◽  
X Ray

Introduction: Congenital Syphilis (CS) occurs through the transplacental transmission of Treponema pallidum in inadequately treated or non-treated pregnant women, and is capable of severe consequences such as miscarriage, preterm birth, congenital disease and/or neonatal death. CS has been showing an increasing incidence worldwide, with an increase of 208% from 2009 to 2015 in Brazil. Case report: 2-month old infant receives care in emergency service due to edema of right lower limb with pain in mobilization. X-ray with osteolytic lesion in distal fibula. Infant was sent to the Pediatrics Oncology clinic. Perinatal data: 7 prenatal appointments, negative serology at 10 and 30 weeks of gestation. End of pregnancy tests were not examined and tests for mother’s hospital admission were not requested. Mother undergone elective cesarean section at 38 weeks without complications. During the pediatric oncologist appointment, patient showed erythematous-squamous lesions in neck and other scar-like lesions in upper body. A new X-ray of lower limbs showed lesions in right fibula with periosteal reaction associated with aggressive osteolytic lesion compromising distal diaphysis, with cortical bone rupture and signs of pathological fracture, suggestive of eosinophilic granuloma. She was hospitalized for a lesion biopsy. Laboratory tests: hematocrit: 23.1 / hemoglobin 7.7 / leukocytes 10,130 (without left deviation) / platelets 638,000 / Negative Cytomegalovirus IgG and IgM and Toxoplasmosis IgG and IgM / VDRL 1:128. Congenital syphilis diagnosis with skin lesions, bone alterations and anemia. Lumbar puncture: glucose 55 / total proteins 26 / VDRL non reagent / 13 leukocytes (8% neutrophils; 84% monomorphonuclear; 8% macrophages) and 160 erythrocytes / negative VDRL and culture. X-ray of other long bones, ophthalmological evaluation and abdominal ultrasound without alterations. Patient was hospitalized for 14 days for treatment with Ceftriaxone 100mg/kg/day, due to the lack of Crystalline Penicillin in the hospital. She is now under outpatient follow-up. Discussion: CS is responsible for high rates of morbidity and mortality. The ongoing increase of cases of this pathology reflects a severe health issue and indicates failures in policies for the prevention of sexually transmitted diseases, with inadequate follow-up of prenatal and maternity protocols.

TBE in United Kingdom

2020 ◽  
Keyword(s):  
United Kingdom ◽  
Clinical Disease ◽  
England And Wales ◽  
Probable Case ◽  
The United Kingdom ◽  
South West ◽  
Louping Ill ◽  
The Uk ◽  
North And South ◽  
South West England

Until 2019, TBE was considered only to be an imported disease to the United Kingdom. In that year, evidence became available that the TBEV is likely circulating in the country1,2 and a first “probable case” of TBE originating in the UK was reported.3 In addition to TBEV, louping ill virus (LIV), a member of the TBEV-serocomplex, is also endemic in parts of the UK. Reports of clinical disease caused by LIV in livestock are mainly from Scotland, parts of North and South West England and Wales.4

Epidemiological Characterization of the Infection by Treponema Pallidum in Pregnant Women in Beira City, Sofala, Mozambique

2020 ◽  
Vol 2 (2) ◽  
Author(s):  
Nchowela Guido
Keyword(s):  
Pregnant Women ◽  
Congenital Syphilis ◽  
Health Centre ◽  
Treponema Pallidum ◽  
Timely Manner ◽  
Pregnancy And Childbirth ◽  
Epidemiological Characterization ◽  
Active Syphilis ◽  
Structured Questionnaire

Introduction: Syphilis is one of several diseases that can be transmitted during pregnancy and childbirth, which can lead to complications during pregnancy and in the newborn. This is especially so when the pregnant woman is not diagnosed or treated properly and in a timely manner. Methodology: Data from 262 pregnant women prospectively included, aged 18-41years, attended at the Ponta Gêa Health Centre for antenatal clinics has been analyzed from January to September of 2016. In the prospective study, a rapid treponemal and a non-treponemal test were performed. A structured questionnaire was used to collect socio demographic and clinical variables, which was developed from the literature review. Results: The prevalence of active syphilis was 11.8%; the majority of reactive pregnant women were aged 18-25years (55.4%), (61.3%) of pregnant women were treated with doses below those recommended; only a small number of the partners were treated successfully. The highest seroprevalence of syphilis was found in housewives (77%), in those who attended primary education (71.6%) in those who had a monthly income of 1000- 3000 MZN (70.3%), in those with two or more pregnancies (55.7%) and living with someone has husband and wife (63.5%). The syphilis/HIV co-infection rate was high. Conclusion: According to the results obtained in this study, urgent measures are needed to assess the problems encountered and to improve the screening approach, treatment and monitoring of syphilis during pregnancy in order to prevent the cases of congenital syphilis.

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