Partial immunity and SARS-CoV-2 mutations—Response

Science ◽  
2021 ◽  
Vol 372 (6540) ◽  
pp. 354.2-355
Author(s):  
Chadi M. Saad-Roy ◽  
Sinead E. Morris ◽  
C. Jessica E. Metcalf ◽  
Michael J. Mina ◽  
Rachel E. Baker ◽  
...  
Keyword(s):  
Partial Immunity

scholarly journals Induction of partial immunity in both males and females is sufficient to protect females against sexual transmission of Chlamydia

2015 ◽  
Vol 9 (4) ◽  
pp. 1076-1088 ◽  
Author(s):  
C P O'Meara ◽  
C W Armitage ◽  
A Kollipara ◽  
D W Andrew ◽  
L Trim ◽  
...  
Keyword(s):  
Sexual Transmission ◽  
Males And Females ◽  
Partial Immunity

scholarly journals Implications of partial immunity on the prospects for tuberculosis control by post-exposure interventions

2007 ◽  
Vol 248 (4) ◽  
pp. 608-617 ◽  
Author(s):  
M. Gabriela M. Gomes ◽  
Paula Rodrigues ◽  
Frank M. Hilker ◽  
Natalia B. Mantilla-Beniers ◽  
Marion Muehlen ◽  
...  
Keyword(s):  
Tuberculosis Control ◽  
Post Exposure ◽  
Partial Immunity

scholarly journals Does infection with Chlamydia trachomatis induce long-lasting partial immunity? Insights from mathematical modelling

2018 ◽  
Vol 95 (2) ◽  
pp. 115-121 ◽  
Author(s):  
Ryosuke Omori ◽  
Hiam Chemaitelly ◽  
Christian L Althaus ◽  
Laith J Abu-Raddad
Keyword(s):  
Chlamydia Trachomatis ◽  
Natural History ◽  
Sexual Risk ◽  
Vaccine Development ◽  
Sensitivity Analyses ◽  
Infectious Period ◽  
Model Structure ◽  
Uncertainty Interval ◽  
The Impact ◽  
Partial Immunity

ObjectivesTo explore whether existence of long-lasting partial immunity against reinfection with Chlamydia trachomatis is necessary to explain C. trachomatis prevalence patterns by age and sexual risk, and to provide a plausible estimate for the effect size, defined here as a reduction in susceptibility to reinfection.MethodsA population-based mathematical model was constructed to describe C. trachomatis natural history and transmission dynamics by age and sexual risk. The model was parameterised using natural history, and epidemiological and sexual behaviour data, and applied for UK and US data. Sensitivity analyses were conducted to assess the robustness of predictions to variations in model structure and to examine the impact of alternative assumptions for the mechanism underlying partial immunity.ResultsPartial immunity against reinfection was found necessary to explain observed C. trachomatis prevalence patterns by age and sexual risk. The reduction in susceptibility to reinfection was estimated at 93% using UK data (95% uncertainty interval (UI)=88%–97%) and at 67% using US data (95% UI=24%–88%). The model-structure sensitivity analyses affirmed model predictions. The immunity-mechanism sensitivity analyses suggested a mechanism of susceptibility reduction against reinfection or a mechanism of infectious-period duration reduction upon reinfection.ConclusionsA strong long-lasting partial immunity against C. trachomatis reinfection should be present to explain observed prevalence patterns. The mechanism of immunity could be either a reduction in susceptibility to reinfection or a reduction in duration of infection on reinfection. C. trachomatis infection appears to naturally elicit a strong long-lasting immune response, supporting the concept of vaccine development.

Take-all distribution and soil type on Chalky Boulder Clay

1986 ◽  
Vol 106 (1) ◽  
pp. 61-66 ◽  
Author(s):  
J. A. Catt ◽  
R. J. Gutteridge ◽  
D. B. Slope
Keyword(s):  
Winter Wheat ◽  
Grain Yield ◽  
Soil Type ◽  
Soil Characteristics ◽  
Soil Types ◽  
Exchangeable Potassium ◽  
Boulder Clay ◽  
Extractable Phosphorus ◽  
Take All ◽  
Partial Immunity

SUMMARYIn 1980 a field of winter wheat at Little Raveley, Cambridgeshire (U.K.) suffered a bad attack of take-all, which was confined mainly to areas dominated by Ragdale series, one of five soil types on the field. Take-all and yield were assessed on experimental areas within the field in the three subsequent years (1981–3). On a strip 50 m wide, which was sown with wheat in each of these years, take-all was in decline and although slight differences in take-all occurred between some of the soil types, they had no effect on grain yield. Following a break crop of beans in 1981, the remainder of the field carried wheat in 1982 and 1983. Here take-all was generally less and yields generally greater in the area that suffered the 1980 attack, probably because it had developed a natural partial immunity to the disease. However, measurements of takeall in relation to soil characteristics on 1 m2 plots suggested that the disease was becoming more prevalent on soils that are less well drained in winter, are more deeply decalcified, and contain less extractable phosphorus or more exchangeable potassium.

Epidemics with partial immunity to reinfection

2010 ◽  
Vol 228 (2) ◽  
pp. 153-159 ◽  
Author(s):  
Guy Katriel
Keyword(s):  
Partial Immunity

scholarly journals Relapsing encephalomyelitis following transfer of partial immunity to JHM virus

1990 ◽  
Vol 8 (5) ◽  
pp. 305-314 ◽  
Author(s):  
Richard A. Shubin ◽  
Mark A. Sussman ◽  
John O. Fleming ◽  
Stephen A. Stohlman
Keyword(s):  
Partial Immunity
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