scholarly journals An investigation of transmission control measures during the first 50 days of the COVID-19 epidemic in China

Science ◽  
2020 ◽  
Vol 368 (6491) ◽  
pp. 638-642 ◽  
Author(s):  
Huaiyu Tian ◽  
Yonghong Liu ◽  
Yidan Li ◽  
Chieh-Hsi Wu ◽  
Bin Chen ◽  
...  
Keyword(s):  
Emergency Response ◽  
Case Reports ◽  
Human Movement ◽  
Health Interventions ◽  
Control Measures ◽  
Wuhan City ◽  
Data Set ◽  
Novel Coronavirus ◽  
National Emergency ◽  
And Control

Responding to an outbreak of a novel coronavirus [agent of coronavirus disease 2019 (COVID-19)] in December 2019, China banned travel to and from Wuhan city on 23 January 2020 and implemented a national emergency response. We investigated the spread and control of COVID-19 using a data set that included case reports, human movement, and public health interventions. The Wuhan shutdown was associated with the delayed arrival of COVID-19 in other cities by 2.91 days. Cities that implemented control measures preemptively reported fewer cases on average (13.0) in the first week of their outbreaks compared with cities that started control later (20.6). Suspending intracity public transport, closing entertainment venues, and banning public gatherings were associated with reductions in case incidence. The national emergency response appears to have delayed the growth and limited the size of the COVID-19 epidemic in China, averting hundreds of thousands of cases by 19 February (day 50).

scholarly journals The impact of transmission control measures during the first 50 days of the COVID-19 epidemic in China

2020 ◽  
Author(s):  
Huaiyu Tian ◽  
Yonghong Liu ◽  
Yidan Li ◽  
Chieh-Hsi Wu ◽  
Bin Chen ◽  
...  
Keyword(s):  
Emergency Response ◽  
Case Reports ◽  
Human Movement ◽  
Respiratory Illness ◽  
Control Measures ◽  
Travel Restrictions ◽  
Novel Coronavirus ◽  
National Emergency ◽  
And Control ◽  
The Impact

AbstractRespiratory illness caused by a novel coronavirus (COVID-19) appeared in China during December 2019. Attempting to contain infection, China banned travel to and from Wuhan city on 23 January and implemented a national emergency response. Here we evaluate the spread and control of the epidemic based on a unique synthesis of data including case reports, human movement and public health interventions. The Wuhan shutdown slowed the dispersal of infection to other cities by an estimated 2.91 days (95%CI: 2.54-3.29), delaying epidemic growth elsewhere in China. Other cities that implemented control measures pre-emptively reported 33.3% (11.1-44.4%) fewer cases in the first week of their outbreaks (13.0; 7.1-18.8) compared with cities that started control later (20.6; 14.5-26.8). Among interventions investigated here, the most effective were suspending intra-city public transport, closing entertainment venues and banning public gatherings. The national emergency response delayed the growth and limited the size of the COVID-19 epidemic and, by 19 February (day 50), had averted hundreds of thousands of cases across China.One sentence summaryTravel restrictions and the national emergency response delayed the growth and limited the size of the COVID-19 epidemic in China.

scholarly journals Evaluating the effectiveness of measures to control the novel coronavirus disease 2019 in Jilin Province, China

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Qinglong Zhao ◽  
Yao Wang ◽  
Meng Yang ◽  
Meina Li ◽  
Zeyu Zhao ◽  
...  
Keyword(s):  
Prevention And Control ◽  
Good Control ◽  
Asymptomatic Infection ◽  
Jilin Province ◽  
Control Measures ◽  
First Case ◽  
Before And After ◽  
Novel Coronavirus ◽  
Reported Data ◽  
And Control

Abstract Background Based on differences in populations and prevention and control measures, the spread of new coronary pneumonia in different countries and regions also differs. This study aimed to calculate the transmissibility of coronavirus disease 2019 (COVID-19), and to evaluate the effectiveness of measures to control the disease in Jilin Province, China. Methods The data of reported COVID-19 cases were collected, including imported and local cases from Jilin Province as of March 14, 2019. A Susceptible–Exposed–Infectious–Asymptomatic–Recovered/Removed (SEIAR) model was developed to fit the data, and the effective reproduction number (Reff) was calculated at different stages in the province. Finally, the effectiveness of the measures was assessed. Results A total of 97 COVID-19 infections were reported in Jilin Province, among which 45 were imported infections (including one asymptomatic infection) and 52 were local infections (including three asymptomatic infections). The model fit the reported data well (R2 = 0.593, P < 0.001). The Reff of COVID-19 before and after February 1, 2020 was 1.64 and 0.05, respectively. Without the intervention taken on February 1, 2020, the predicted cases would have reached a peak of 177,011 on October 22, 2020 (284 days from the first case). The projected number of cases until the end of the outbreak (on October 9, 2021) would have been 17,129,367, with a total attack rate of 63.66%. Based on the comparison between the predicted incidence of the model and the actual incidence, the comprehensive intervention measures implemented in Jilin Province on February 1 reduced the incidence of cases by 99.99%. Therefore, according to the current measures and implementation efforts, Jilin Province can achieve good control of the virus’s spread. Conclusions COVID-19 has a moderate transmissibility in Jilin Province, China. The interventions implemented in the province had proven effective; increasing social distancing and a rapid response by the prevention and control system will help control the spread of the disease.

The Message of “APEC Blue” for the Prevention and Control of Urban Air Pollution in China

2016 ◽  
Vol 04 (04) ◽  
pp. 1650027
Author(s):  
Rong ZHU
Keyword(s):  
Air Pollution ◽  
Emergency Response ◽  
Prevention And Control ◽  
Urban Air Pollution ◽  
Pollution Prevention ◽  
Warning System ◽  
Weather Conditions ◽  
Control Measures ◽  
Atmospheric Pollutant ◽  
And Control

Analysis of the meteorological conditions for atmospheric pollutant dispersion before and after the 2014 APEC meeting shows very significant effects of air pollution prevention and control measures on the meeting. It proves that the proper measures to control air pollution in the Beijing-Tianjin-Hebei Region are: establishing a regional emergency response mechanism to reduce emissions in the case of heavy air pollution, strengthening the local emergency response measures for emission reduction, and enhancing the early warning system for weather conditions conducive to heavy air pollution.

ESTIMATION OF SARS-COV-2 SPECIFIC ANTIBODIES SEROPREVALENCE IN HEALTHCARE WORKERS IN DISTRICT UDAIPUR, INDIA

2021 ◽  
pp. 61-63
Author(s):  
Shelesh Kumar Swami ◽  
Nitesh Kumar Chauhan ◽  
Shuchi Goyal ◽  
A.K. Verma ◽  
Shweta Biyani
Keyword(s):  
Healthcare Workers ◽  
Clinical Symptoms ◽  
Control Measures ◽  
Rt Pcr ◽  
High Seroprevalence ◽  
Know How ◽  
Novel Coronavirus ◽  
And Control ◽  
Infection Eradication ◽  
Cumulative Prevalence

Background:Current pandemic caused by Novel coronavirus (COVID-19) causes clinical symptoms from fever to acute respiratory distress syndrome but may remain mild or asymptomatic. To evaluate the cumulative prevalence of SARSCoV-2 infection in a community and know how immune response develops in the population, reliable assay alongwith RT-PCR for detection of SARS-CoV 2 antibodies is needed. Healthcare workers (HCWs) represent a high-risk populat - ion for infection with SARS-CoV-2. Methods: We evaluated total antibodies recognizing the SARS CoV 2 receptor binding domain (S1-RBD) - - - or the Spike protein over a period of six months in a total of 310 healthcare workers engaged in hospital using SARS-CoV-2 Total antibody assay kit. Findings: The overall seroprevalence found in our analysis was 41.93%. In case of males the percentage positive was found to be signicantly higher at 43.91%, compared to females at 36.25%. Seroprevalence was signicantly higher in 50 years above age group in comparison to 20-50 years old aged healthcare workers. The seroprevalence was higher in doctors, nursing staff and lab technicians than other healthcare professionals as 44.6%. Conclusions: This study showed high seroprevalence of SARS-CoV-2 in healthcare workers which means remaining proportion of the healthcare workers are still susceptible to the infection. Good compliance to infection eradication and control measures, adequate PPEs, and early detection and isolation of healthcare workers infected with SARS-CoV-2 are mandatory to reduce the risk of SARS-CoV-2 infection.

REVIEW ARTICLE ABOUT PERINATALAND NEONATAL MANAGEMENT FOR THE PREVENTION AND CONTROL OF THE 2019 NOVEL CORONAVIRUS INFECTION

2021 ◽  
pp. 54-57
Author(s):  
Isra Khalil Mohammed Ali Saeed ◽  
Maha Hussein Mohammed Hamza ◽  
Hiba Hussein Ibrahim ◽  
Esmehan Elkheir Babeker ◽  
Ibrahim Ismail M.Abu ◽  
...  
Keyword(s):  
Prevention And Control ◽  
Neonatal Intensive Care ◽  
Control Measures ◽  
Neonatal Intensive Care Units ◽  
Community Physician ◽  
Coronavirus Infection ◽  
Novel Coronavirus ◽  
And Control ◽  
Who Guideline ◽  
Immature Immune System

An epidemic of new coronavirus 2019 (COVID-19) has emerged in China since December 2019. WHO declared it as a pandemic on March 2020 as it has spread worldwide. Several cases among neonate were observed with rst reported 36 hours after birth. Due to the possibility of the infection and the immature immune system of the neonate there should be preventive and control measures at Neonatal Intensive Care Units. According to WHO guideline and other published articles in COVID-19 in infants and neonate a technical working group including community physician and Pediatricians has put measures for clinical management, prevention and control of COVID-19 in neonates.

scholarly journals Times to Key Events in the Course of Zika Infection and their Implications for Surveillance: A Systematic Review and Pooled Analysis

2016 ◽  
Author(s):  
Justin Lessler ◽  
Cassandra T. Ott ◽  
Andrea C. Carcelen ◽  
Jacob M. Konikoff ◽  
Joe Williamson ◽  
...  
Keyword(s):  
Systematic Review ◽  
Blood Supply ◽  
Zika Virus ◽  
Blood Donation ◽  
Case Reports ◽  
Fold Increase ◽  
Pooled Analysis ◽  
Control Measures ◽  
History Of ◽  
And Control

Background Evidence suggests that Zika virus has driven a 10-fold increase in babies born with microcephaly in Brazil, prompting the WHO to declare a Public Health Emergency of International Concern. However, little is known about the natural history of infection. These data are critical for implementation of surveillance and control measures such as protecting the blood supply. Methods We conducted a systematic review and pooled analysis to estimate the distribution of times from Zika infection to symptom onset, seroconversion, and viral clearance, and analyzed their implications for surveillance and blood supply safety. Results Based on 25 case reports, we estimate the median incubation period of Zika virus infection is 5.9 days (95% CI: 4.4-7.6), and that 95% of cases will develop symptoms by 11.1 days post-infection (95% CI: 7.6-18.0). On average seroconversion occurs 9.0 days (95% CI, 7.0-11.6) after infection, and virus is detectable in blood for 9.9 days (95% CI: 6.8-21.4). In 5% of cases detectable virus persists for over 18.9 days (95% CI: 12.6-79.5). The baseline (no screening) risk of a blood donation being infected with Zika increases by approximately 1 in 10,000 for every 1 per 100,000 person-days increase in Zika incidence. Symptom based screening reduces this by 7% (RR 0.93, 93% CI 0.86-0.99), and antibody screening by 29% (RR 0.71, 95% CI: 0.28-0.88). Conclusions Symptom or antibody-based surveillance can do little to reduce the risk of Zika contaminated blood donations. High incidence areas may consider PCR testing to identify lots safe for use in pregnant women.

scholarly journals Consideration of the Management of Pediatric Fever Clinics During the Novel Coronavirus Pneumonia Outbreak

2020 ◽  
pp. 1-7
Author(s):  
Hui Ding ◽  
Zhaoling Shi ◽  
Zhen Ruan ◽  
Xiaoning Cheng ◽  
Ruying Li ◽  
...  
Keyword(s):  
Medical Staff ◽  
Prevention And Control ◽  
Cross Infection ◽  
The Novel ◽  
Wuhan City ◽  
Control Programs ◽  
Treatment And Prevention ◽  
Epidemic Period ◽  
Novel Coronavirus ◽  
And Control

ABSTRACT Since the outbreak of 2019 novel coronavirus (2019-nCoV) infection in Wuhan City, China, pediatric cases have gradually increased. It is very important to prevent cross-infection in pediatric fever clinics, to identify children with fever in pediatric fever clinics, and to strengthen the management of pediatric fever clinics. According to prevention and control programs, we propose the guidance on the management of pediatric fever clinics during the nCoV pneumonia epidemic period, which outlines in detail how to optimize processes, prevent cross-infection, provide health protection, and prevent disinfection of medical staff. The present consideration statement summarizes current strategies on the pre-diagnosis, triage, diagnosis, treatment, and prevention of 2019-nCoV infection, which provides practical suggestions on strengthening the management of pediatric fever clinics during the nCoV pneumonia epidemic period.

scholarly journals Notes from the Field: Effectiveness of Prevention and Control Measures for Imported COVID-19 in Guangming District of Shenzhen

2020 ◽  
pp. 016327872097183
Author(s):  
Xiaoliang Chen ◽  
Tieqiang Wang ◽  
Yang Zhao ◽  
Yunjie Wu ◽  
Ranran Qie ◽  
...  
Keyword(s):  
Prevention And Control ◽  
Local Community ◽  
Management Strategies ◽  
Screening Strategy ◽  
Control Measures ◽  
Imported Cases ◽  
Returning To Work ◽  
Prevention And Control Measures ◽  
Novel Coronavirus ◽  
And Control

Novel coronavirus disease 2019 (COVID-19) was present in most provinces of China after January 2020. We implemented a surveillance and screening strategy that included early detection of laboratory-confirmed COVID-19 cases and people who were exposed to the disease in Guangming District of Shenzhen. Separate targeted treatment and management strategies were applied to confirmed and suspected cases. From January 23 to March 13, 2020, we found 12 suspected cases, and 11 were confirmed as positive. Although eight of the 11 confirmed cases were family-aggregated, they were all imported cases with common exposure, which did not further cause local community transmission, and no medical staff were infected. After February 14, when the last case was confirmed, there were no newly confirmed cases for 28 consecutive days under the strict outbreak control. The targeted and whole-society involved prevention and control measures prevented the spread of the disease in a very short time and provided a strong guarantee for the orderly recovery of returning to work and social activities.

scholarly journals Development of research on COVID-19 by the World Scientific Community in the first half of 2020

Bionatura ◽  
2020 ◽  
Vol 5 (4) ◽  
pp. 1410-1417
Author(s):  
Daniel Tinôco ◽  
Suzana Borschiver
Keyword(s):  
Scientific Community ◽  
Control Measures ◽  
Activity Period ◽  
World Scientific ◽  
Case Identification ◽  
The World ◽  
Prevention And Control Measures ◽  
Health Complications ◽  
Novel Coronavirus ◽  
And Control

The World Scientific Community has carried out several studies on the novel coronavirus, responsible for the current COVID-19 pandemic. This study aimed to verify the development level and research evolution on COVID-19, summarizing experts' main trends in the first half of 2020. The most cited articles focused on understanding the disease, addressing aspects of its transmission, viral activity period, symptoms, health complications, risk factors, and the estimate of new cases. These papers also focused on the treatment/prevention and management of COVID-19. Several drugs and alternative treatments have been investigated, such as the convalescent plasma transfusion and stem cell transplantation, while an efficient vaccine is developed. Prevention and control measures, such as social isolation and immediate case identification, were also investigated. Therefore, the main COVID-19 trends were identified and classified in disease, treatment/prevention, and pandemic management, contributing to scientific understanding and future studies.

scholarly journals Internet Hospitals Help Prevent and Control the Epidemic of COVID-19 in China: Multicenter User Profiling Study (Preprint)

2020 ◽  
Author(s):  
Kai Gong ◽  
Zhong Xu ◽  
Zhefeng Cai ◽  
Yuxiu Chen ◽  
Zhanxiang Wang
Keyword(s):  
Prevention And Control ◽  
Control Measures ◽  
User Profiling ◽  
Kappa Score ◽  
Factors Affecting ◽  
Logistic Regression Models ◽  
The Public ◽  
The Social ◽  
Novel Coronavirus ◽  
And Control

BACKGROUND During the spread of the novel coronavirus disease (COVID-19), internet hospitals in China were engaged with epidemic prevention and control, offering epidemic-related online services and medical support to the public. OBJECTIVE The aim of this study is to explore the role of internet hospitals during the prevention and control of the COVID-19 outbreak in China. METHODS Online epidemic-related consultations from multicenter internet hospitals in China during the COVID-19 epidemic were collected. The counselees were described and classified into seven type groups. Symptoms were recorded and compared with reported patients with COVID-19. Hypochondriacal suspicion and offline visit motivation were detected within each counselees’ group to evaluate the social panic of the epidemic along with the consequent medical-seeking behaviors. The counselees’ motivation and the doctors’ recommendation for an offline visit were compared. Risk factors affecting the counselees’ tendency of hypochondriacal suspicion and offline visit motivation were explored by logistic regression models. The epidemic prevention and control measures based on internet hospitals were listed, and the corresponding effects were discussed. RESULTS A total of 4913 consultations were enrolled for analysis with the median age of the counselees at 28 years (IQR 22-33 years). There were 104 (2.12%) healthy counselees, 147 (2.99%) hypochondriacal counselees, 34 (0.69%) exposed counselees, 853 (17.36%) mildly suspicious counselees, 42 (0.85%) moderately suspicious counselees, 3550 (72.26%) highly suspicious counselees, and 183 (3.72%) severely suspicious counselees. A total of 94.20% (n=4628) of counselees had epidemic-related symptoms with a distribution similar to those of COVID-19. The hypochondriacal suspicion (n=2167, 44.11%) was common. The counselees’ motivation and the doctors’ recommendation for offline visits were inconsistent (<i>P</i>&lt;.001) with a Cohen kappa score of 0.039, indicating improper medical-seeking behaviors. Adult counselees (odds ratio [OR]=1.816, <i>P</i>&lt;.001) with epidemiological exposure (OR 7.568, <i>P</i>&lt;.001), shortness of breath (OR 1.440, <i>P</i>=.001), diarrhea (OR 1.272, <i>P</i>=.04), and unrelated symptoms (OR 1.509, <i>P</i>&lt;.001) were more likely to have hypochondriacal suspicion. Counselees with severe illnesses (OR 2.303, <i>P</i>&lt;.001), fever (OR 1.660, <i>P</i>&lt;.001), epidemiological exposure history (OR 1.440, <i>P</i>=.01), and hypochondriacal suspicion (OR 4.826, <i>P</i>&lt;.001) were more likely to attempt an offline visit. Reattending counselees (OR 0.545, <i>P</i>=.002) were less motivated to go to the offline clinic. CONCLUSIONS Internet hospitals can serve different types of epidemic counselees, offer essential medical supports to the public during the COVID-19 outbreak, reduce the social panic, promote social distancing, enhance the public’s ability of self-protection, correct improper medical-seeking behaviors, reduce the chance of nosocomial cross-infection, and facilitate epidemiological screening, thus, playing an important role on preventing and controlling COVID-19.

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