scholarly journals Comment on “Large-scale GWAS reveals insights into the genetic architecture of same-sex sexual behavior”

Science ◽  
2021 ◽  
Vol 371 (6536) ◽  
pp. eaba2941
Author(s):  
Dean Hamer ◽  
Brian Mustanski ◽  
Randall Sell ◽  
Stephanie A. Sanders ◽  
Justin R. Garcia

The phenotypic measures used by Ganna et al. (Research Articles, 30 August 2019, p. 882) lump together predominantly heterosexual, bisexual, and homosexual individuals, including those who have experimented with a same-sex partner only once. This may have resulted in misleading associations to personality traits unrelated to understood categories of human sexuality. Scientific studies of human sexuality should use validated and reliable measures of sexual behaviors, attractions, and identities that capture the full spectrum of complexity.

Science ◽  
2021 ◽  
Vol 371 (6536) ◽  
pp. eaba5693
Author(s):  
Andrea Ganna ◽  
Karin J. H. Verweij ◽  
Michel G. Nivard ◽  
Robert Maier ◽  
Robbee Wedow ◽  
...  

Hamer et al. argue that the variable “ever versus never had a same-sex partner” does not capture the complexity of human sexuality. We agree and said so in our paper. But Hamer et al. neglect to mention that we also reported follow-up analyses showing substantial overlap of the genetic influences on our main variable and on more nuanced measures of sexual behavior, attraction, and identity.


Science ◽  
2019 ◽  
Vol 365 (6456) ◽  
pp. eaat7693 ◽  
Author(s):  
Andrea Ganna ◽  
Karin J. H. Verweij ◽  
Michel G. Nivard ◽  
Robert Maier ◽  
Robbee Wedow ◽  
...  

Twin and family studies have shown that same-sex sexual behavior is partly genetically influenced, but previous searches for specific genes involved have been underpowered. We performed a genome-wide association study (GWAS) on 477,522 individuals, revealing five loci significantly associated with same-sex sexual behavior. In aggregate, all tested genetic variants accounted for 8 to 25% of variation in same-sex sexual behavior, only partially overlapped between males and females, and do not allow meaningful prediction of an individual’s sexual behavior. Comparing these GWAS results with those for the proportion of same-sex to total number of sexual partners among nonheterosexuals suggests that there is no single continuum from opposite-sex to same-sex sexual behavior. Overall, our findings provide insights into the genetics underlying same-sex sexual behavior and underscore the complexity of sexuality.


2020 ◽  
Author(s):  
Laura Lindberg ◽  
Lauren Firestein ◽  
Cynthia Beavin

This study examines changes over time, and demographic differentials, in the prevalence of select sexual behaviors and contraceptive use measures in a national sample of US adolescents. We used data on female and male adolescents aged 15-19 from the 2006-2010 (N=4,662), 2011-2015 (N=4,134), and 2015-2017 (N=1,810) National Survey of Family Growth. Logistic regression was used to identify differences between periods by gender, and for some measures by age, in sexual behaviors (penile-vaginal intercourse (PVI), oral or anal sex with an opposite-sex partner, sexual experience with a same-sex partner), contraceptive use and condom consistency. We estimated probabilities of age at first PVI with Kaplan-Meier failure analysis and tested for changes over time and differences by gender. Over half of all adolescents have engaged in at least one of the sexual behaviors measured. Between 2011-2015 and 2015-2017, males age 15-17 reported significant declines in all but same-sex partners, while the prevalence of sexual behaviors among older males and adolescent females overall remained generally stable. In each period, females were more likely than males to report a same-sex partner. Age of first PVI increased, but by age 17 the difference between time periods is minimal. Adolescent females report increases in the use at last sex of long-acting reversible contraceptive methods (3% to 18%) and multiple methods (27% to 41%). The condom use measures did not change over time. These findings identify components of both stability and change in adolescent sexual and contraceptive behavior in the last decade. Implications This analysis contributes a timely update on trends in adolescent sexual behavior and contraceptive use, showing that adolescents’ behaviors are complex and evolving. Sexual health information and services must be available so that young people have the resources to make healthy and responsible choices for themselves and their partners.


Author(s):  
Ganna A ◽  
Verweij KJH ◽  
Nivard MG ◽  
Maier R ◽  
Wedow R ◽  
...  

2002 ◽  
Vol 30 (3) ◽  
pp. 209-227 ◽  
Author(s):  
Mark A. Yarhouse ◽  
Lori A. Burkett ◽  
Elizabeth M. Kreeft

Paraprofessional Christian ministries for sexual behavior and same-sex identity concerns have grown significantly in recent years. Some ministries are affiliated with organizations that have specific standards for affiliation; others are independent. Some emphasize change of sexual orientation; others promote change of behavior and chastity. Some ministries provide services exclusively to homosexuals; others provide resources to homosexuals and heterosexuals alike. This paper reviews similarities and differences among paraprofessional Christian ministries for persons struggling with sexual behaviors and same-sex identity concerns. Similarities and differences are related to (a) mission/vision, (b) view of etiology, (c) method of intervention, (d) format, and (e) definition of success. Christian ministries include Exodus International-affiliated ministries, independent Christian ministries, Homosexuals Anonymous, and Courage. Impressions from the review of the various Christian ministries are also offered, including recommendations for making appropriate referrals.


PEDIATRICS ◽  
1991 ◽  
Vol 88 (3) ◽  
pp. 456-464 ◽  
Author(s):  
William N. Friedrich ◽  
Patricia Grambsch ◽  
Daniel Broughton ◽  
James Kuiper ◽  
Robert L. Beilke

A large-scale, community-based survey was done to assess the frequency of a wide variety of sexual behaviors in normal preadolescent children and to measure the relationship of these behaviors to age, gender, and socioeconomic and family variables. A sample of 880 2-through 12-year-old children screened to exclude those with a history of sexual abuse were rated by their mothers using several questionnaire measures. The frequency of different behaviors varied widely, with more aggressive sexual behaviors and behaviors imitative of adults being rare. Older children (both boys and girls) were less sexual than younger children. Sexuality was found to be related to the level of general behavior problems, as measured by the Achenbach Internalizing and Externalizing T scores and to a measure of family nudity. It was not related to socioeconomic variables.


2021 ◽  
Author(s):  
Christopher D Petsko ◽  
Tony Silva ◽  
Stefan Vogler

In the United States, people perceive men’s masculinity to be more precarious, or easier to lose, than women’s femininity. In the present manuscript, we investigated (1) whether men’s heterosexuality is likewise perceived to be more precarious than women’s, and if so, (2) whether this effect is exaggerated when the targets in question are Black rather than White. To investigate these questions, we conducted a large-scale (N = 3,010), nationally representative experiment in which participants read about a target person who either did or did not engage in a single same-sex sexual behavior. Results revealed that participants questioned the heterosexuality of men more than the heterosexuality of women when they engaged (vs. did not engage) in a same-sex sexual behavior. Surprisingly, these effects were not moderated by whether targets were Black vs. White. In other words, men’s heterosexuality was indeed perceived to be more precarious than women’s, irrespective of targets’ race.


Behaviour ◽  
1980 ◽  
Vol 75 (1-2) ◽  
pp. 1-21 ◽  
Author(s):  
Michael H. Figler ◽  
Harry W. Cole ◽  
Harman V.S. Peeke ◽  
Frederick J. Parente

AbstractC. nigrofasciatum have been widely used as a preparation in the investigation of aggressive (threat/attack) behavior because of their reputation as a highly aggressive species. They have also frequently been used in studies of learning processes, especially habituation. The reproductive and aggressive behaviors of the family Cichlidae have been described extensively, however, the sexual behavior of C. nigrofasciatum has been treated only cursorily. Several investigators have postulated a mutually inhibitory relationship between sex and aggression such that any decrease in the level of one of these motivational states results in an increase in the level of the other. In order to test this hypothesized relationship between sex and aggression, male and female C. nigrofasciatum were exposed to either male or female stimulus fish for 24 consecutive hours. In the present investigation, performance of sexual behavior was found to inhibit performance of aggressive behavior and vice versa. A principle components statistical analysis was performed in order to reduce the number of dependent variables to a smaller number of underlying clusters of variables referred to as factors. The principle components analysis indicated that the data were characterized by two orthogonal factors, the first of which reflected qualitative differences between the sex and aggression variables, suggesting that a mutually inhibitory relationship exists between sex and aggression. Discriminant analyses indicated that females initiate courtship and perform more aggressive behaviors than males, males elicit more aggression than females, opposite sex dyads perform more sexual behaviors than same sex dyads, and same sex dyads perform more aggressive behaviors than opposite sex dyads. Habituation of aggression was demonstrated in all dyads. Significant decrements in sexual behaviors were not observed.


Author(s):  
Glynis Murphy ◽  
Clare Melvin

The vast majority of individuals with autism do not commit sexual offenses. While there has been some suggestion of a tendency towards anti-social or offending behaviors, a propensity for breaking the law by those with a diagnosis of autism spectrum disorder has not been found in the research literature. However, the small number of individuals with autism spectrum disorder who do commit crimes appear to cover the full spectrum of offenses committed by offenders without autism spectrum disorder, including sexual offences, arson, violence, theft, terrorism, and manslaughter, although large scale studies suggest they tend to commit proportionately fewer property, driving, and drug offences. The purpose of this case study is to present the use of cognitive behavior therapy to therapeutically address the problem sexual behaviors of a young man with ASD.


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