Direct observation of structure-function relationship in a nucleic acid-processing enzyme

M. J. Comstock; K. D. Whitley; H. Jia; J. Sokoloski; T. M. Lohman; T. Ha; Y. R. Chemla

doi:10.1126/science.aaa0130

Direct observation of structure-function relationship in a nucleic acid-processing enzyme

Science ◽

10.1126/science.aaa0130 ◽

2015 ◽

Vol 348 (6232) ◽

pp. 352-354 ◽

Cited By ~ 104

Author(s):

M. J. Comstock ◽

K. D. Whitley ◽

H. Jia ◽

J. Sokoloski ◽

T. M. Lohman ◽

...

Keyword(s):

Nucleic Acid ◽

Structure Function ◽

Direct Observation ◽

Processing Enzyme ◽

Structure Function Relationship ◽

Acid Processing ◽

Function Relationship

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Faculty Opinions recommendation of Protein structure. Direct observation of structure-function relationship in a nucleic acid-processing enzyme.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.725439068.793549726 ◽

2018 ◽

Author(s):

Joyce Lebbink

Keyword(s):

Protein Structure ◽

Nucleic Acid ◽

Structure Function ◽

Direct Observation ◽

Processing Enzyme ◽

Structure Function Relationship ◽

Acid Processing ◽

Function Relationship

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Direct Observation of Structure-Function Relationships in Nucleic Acid Processing Enzymes

Biophysical Journal ◽

10.1016/j.bpj.2014.11.035 ◽

2015 ◽

Vol 108 (2) ◽

pp. 4a

Author(s):

Yann Chemla

Keyword(s):

Nucleic Acid ◽

Structure Function ◽

Direct Observation ◽

Processing Enzymes ◽

Acid Processing

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2P028 Direct observation of antigen-antibody complex : Effects of antigen size, valence, and binding affinity of antibody(Proteins-structure and structure-function relationship,Oral Presentations)

Seibutsu Butsuri ◽

10.2142/biophys.47.s120_1 ◽

2007 ◽

Vol 47 (supplement) ◽

pp. S120

Author(s):

Maiko Koga ◽

Kouta Mayanagi ◽

Aki Kitai ◽

Akikazu Murakami ◽

Takachika Azuma ◽

...

Keyword(s):

Structure Function ◽

Binding Affinity ◽

Direct Observation ◽

Structure Function Relationship ◽

Antibody Complex ◽

Function Relationship ◽

Antigen Antibody ◽

Oral Presentations

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Synthesis, Anticancer Activity, Structure‐Function Relationship and Mechanism Investigation of Falcarindiol Analogues

ChemMedChem ◽

10.1002/cmdc.202100377 ◽

2021 ◽

Author(s):

Wan-Li Tan ◽

Chun Zhang ◽

Yang Li ◽

Kai Guo ◽

Xiao-Wei Gao ◽

...

Keyword(s):

Structure Function ◽

Anticancer Activity ◽

Activity Structure ◽

Structure Function Relationship ◽

Function Relationship

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Structure-Function Relationship of Human Parathyroid Hormone on Vitamin D Receptor Regulation in Osteoblast-Like Cells (ROS 17/2.8)

Vitamin D ◽

10.1515/9783110882513-085 ◽

1994 ◽

pp. 245-246

Keyword(s):

Vitamin D ◽

Parathyroid Hormone ◽

Structure Function ◽

Vitamin D Receptor ◽

Receptor Regulation ◽

Human Parathyroid Hormone ◽

Structure Function Relationship ◽

Function Relationship ◽

Relationship Of

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The yeast fatty acid synthetase. Structure-function relationship and the role of the active cysteine-SH and pantetheine-SH.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)68852-6 ◽

1981 ◽

Vol 256 (16) ◽

pp. 8364-8370 ◽

Cited By ~ 2

Author(s):

J.K. Stoops ◽

S.J. Wakil

Keyword(s):

Fatty Acid ◽

Structure Function ◽

Fatty Acid Synthetase ◽

Structure Function Relationship ◽

Function Relationship

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Modeling a neural network as a teaching tool for the learning of the structure-function relationship

AJP Advances in Physiology Education ◽

10.1152/advan.00101.2009 ◽

2010 ◽

Vol 34 (3) ◽

pp. 158-161 ◽

Cited By ~ 1

Author(s):

Dino G. Salinas ◽

Cristián Acevedo ◽

Christian R. Gomez

Keyword(s):

Neural Network ◽

Structure Function ◽

Teaching Tool ◽

Structure Function Relationship ◽

Function Relationship

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Linear and Nonlinear Optical Properties of Triphenylamine–Indandione Chromophores: Theoretical Study of the Structure–Function Relationship under the Combined Action of Substituent and Symmetry Change

The Journal of Physical Chemistry A ◽

10.1021/acs.jpca.7b09186 ◽

2018 ◽

Vol 122 (9) ◽

pp. 2344-2352 ◽

Cited By ~ 9

Author(s):

Zeyu Liu ◽

Shugui Hua ◽

Xiufen Yan

Keyword(s):

Optical Properties ◽

Structure Function ◽

Nonlinear Optical ◽

Theoretical Study ◽

Nonlinear Optical Properties ◽

Structure Function Relationship ◽

Combined Action ◽

Linear And Nonlinear ◽

Function Relationship ◽

Symmetry Change

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Solution Structure of the Human Oncogenic Protein Gankyrin Containing Seven Ankyrin Repeats and Analysis of Its Structure−Function Relationship†,‡

Biochemistry ◽

10.1021/bi049116o ◽

2004 ◽

Vol 43 (38) ◽

pp. 12152-12161 ◽

Cited By ~ 25

Author(s):

Chunhua Yuan ◽

Junan Li ◽

Anjali Mahajan ◽

Ming Jye Poi ◽

In-Ja L. Byeon ◽

...

Keyword(s):

Structure Function ◽

Solution Structure ◽

Ankyrin Repeats ◽

Structure Function Relationship ◽

Function Relationship ◽

Oncogenic Protein

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3P024 Model study of the desiccation-induced structural transformations of Group-3 Late Embryogenesis Abundant (G3LEA) proteins(Hemeproteins. Electronic states. Proteins-structure and structure-function relationship,Oral Presentations)

Seibutsu Butsuri ◽

10.2142/biophys.47.s209_1 ◽

2007 ◽

Vol 47 (supplement) ◽

pp. S209

Author(s):

Tempei Shimizu ◽

Shohei Miyama ◽

Takao Furuki ◽

Yasushi Kanamori ◽

Takahiro Kikawada ◽

...

Keyword(s):

Structure Function ◽

Electronic States ◽

Structural Transformations ◽

Late Embryogenesis Abundant ◽

Model Study ◽

Late Embryogenesis ◽

Structure Function Relationship ◽

Group 3 ◽

Function Relationship ◽

Oral Presentations

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