Induction of olfactory receptor sensitivity in mice

H. Wang; C. Wysocki; G. Gold

doi:10.1126/science.8493539

Induction of olfactory receptor sensitivity in mice

Science ◽

10.1126/science.8493539 ◽

1993 ◽

Vol 260 (5110) ◽

pp. 998-1000 ◽

Cited By ~ 118

Author(s):

H. Wang ◽

C. Wysocki ◽

G. Gold

Keyword(s):

Olfactory Receptor ◽

Receptor Sensitivity

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Specific enhancement of olfactory receptor sensitivity associated with foetal learning of food odors in the rabbit

The Science of Nature ◽

10.1007/bf01177279 ◽

1995 ◽

Vol 82 (3) ◽

pp. 148-149 ◽

Cited By ~ 72

Author(s):

E. Semke ◽

H. Distel ◽

R. Hudson

Keyword(s):

Olfactory Receptor ◽

Receptor Sensitivity ◽

Specific Enhancement ◽

Food Odors

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Genetically variable olfactory receptor sensitivity in

Life Sciences ◽

10.1016/0024-3205(75)90245-3 ◽

1975 ◽

Vol 17 (1) ◽

pp. 105-110 ◽

Cited By ~ 13

Author(s):

Jack M. Rozental ◽

Dale M. Norris

Keyword(s):

Olfactory Receptor ◽

Receptor Sensitivity

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Induction of Olfactory Receptor Sensitivity in Mice

Olfaction and Taste XI ◽

10.1007/978-4-431-68355-1_93 ◽

1994 ◽

pp. 240-240

Author(s):

Hai-Wei Wang ◽

Charles J. Wysocki ◽

Geoffrey H. Gold

Keyword(s):

Olfactory Receptor ◽

Receptor Sensitivity

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Minimum Odorant Concentrations Detectable by the Dog and Their Implications for Olfactory Receptor Sensitivity

Chemical Signals in Vertebrates ◽

10.1007/978-1-4684-2364-8_25 ◽

1977 ◽

pp. 455-464 ◽

Cited By ~ 11

Author(s):

David G. Moulton

Keyword(s):

Olfactory Receptor ◽

Receptor Sensitivity

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Specific Enhancement of Olfactory Receptor Sensitivity Associated with Foetal Learning of Food Odors in the Rabbit

The Science of Nature ◽

10.1007/s001140050160 ◽

1995 ◽

Vol 82 (3) ◽

pp. 148-149 ◽

Cited By ~ 1

Author(s):

E. Semke ◽

H. Distel ◽

R. Hudson

Keyword(s):

Olfactory Receptor ◽

Receptor Sensitivity ◽

Specific Enhancement ◽

Food Odors

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Ultrastructural aspects of olfactory signal transduction and its development

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s042482010016844x ◽

1994 ◽

Vol 52 ◽

pp. 142-143

Author(s):

Bert Ph. M. Menco

Keyword(s):

Signal Transduction ◽

Olfactory Receptor ◽

Receptor Cell ◽

Freeze Substitution ◽

Luminal Surface ◽

Tissue Sections ◽

Olfactory Receptor Cells ◽

Receptor Cells ◽

Olfactory Signal ◽

Odor Molecule

Vertebrate olfactory receptor cells are specialized neurons that have numerous long tapering cilia. The distal parts of these cilia line the interface between the external odorous environment and the luminal surface of the olfactory epithelium. The length and number of these cilia results in a large surface area that presumably increases the chance that an odor molecule will meet a receptor cell. Advanced methods of cryoprepration and immuno-gold labeling were particularly useful to preserve the delicate ultrastructural and immunocytochemical features of olfactory cilia required for localization of molecules involved in olfactory signal-transduction. We subjected olfactory tissues to freeze-substitution in acetone (unfixed tissues) or methanol (fixed tissues) followed by low temperature embedding in Lowicryl K11M for that purpose. Tissue sections were immunoreacted with several antibodies against proteins that are presumably important in olfactory signal-transduction.

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