Gene therapy. NIH picks three gene vector centers

Science ◽  
1995 ◽  
Vol 269 (5225) ◽  
pp. 751-752 ◽  
Author(s):  
E. Marshall
Keyword(s):  
Gene Therapy ◽  
Gene Vector

A tumor targeted gene vector modified with G250 monoclonal antibody for gene therapy

2008 ◽  
Vol 127 (2) ◽  
pp. 173-179 ◽  
Author(s):  
Yajun Duan ◽  
Junnian Zheng ◽  
Sufang Han ◽  
Yi Wu ◽  
Yanming Wang ◽  
...  
Keyword(s):  
Gene Therapy ◽  
Monoclonal Antibody ◽  
Gene Vector

The research of nanoparticles as gene vector for tumor gene therapy

2014 ◽  
Vol 89 (3) ◽  
pp. 352-357 ◽  
Author(s):  
Nian-feng Sun ◽  
Zhan-ao Liu ◽  
Wen-bai Huang ◽  
Ai-ling Tian ◽  
San-yuan Hu
Keyword(s):  
Gene Therapy ◽  
Gene Vector ◽  
Tumor Gene Therapy ◽  
Tumor Gene

Novel Organic-Inorganic Hybrid Nanoparticles as Non-Viral Gene Vector

2008 ◽  
Vol 47-50 ◽  
pp. 1319-1322
Author(s):  
Yang Zhao ◽  
Pei Yin ◽  
Zu Yong Wang ◽  
Lei Ren ◽  
Qi Qing Zhang
Keyword(s):  
Gene Therapy ◽  
Encapsulation Efficiency ◽  
Sol Gel ◽  
Hybrid Nanoparticles ◽  
Viral Gene ◽  
Gene Vector ◽  
Inorganic Hybrid ◽  
Sol Gel Process ◽  
Gene Vectors

Novel hybrid biomaterial of gelatin-siloxane nanoparticles (GS NPs), with positive surface potential and lower cytotoxicity, was synthesized through a 2-step sol-gel process. The pDNA-GS NPs complex was formulated with high encapsulation efficiency, and exhibited and efficient transfection in vitro. We thus envision that the GS NPs material could serve as non-viral gene vectors for gene therapy.

scholarly journals A preliminary study of Parkinson’s gene therapy via sono-magnetic sensing gene vector for conquering extra/intracellular barriers in mice

2020 ◽  
Vol 13 (3) ◽  
pp. 786-799 ◽  
Author(s):  
Chun-Yao Wu ◽  
Rih-Yang Huang ◽  
En-Chi Liao ◽  
Yu-Chun Lin ◽  
Yi-Ju Ho ◽  
...  
Keyword(s):  
Gene Therapy ◽  
Gene Vector ◽  
Magnetic Sensing ◽  
Preliminary Study

scholarly journals Surface Modification of Gelatin Nanoparticles with Polyethylenimine as Gene Vector

2011 ◽  
Vol 2011 ◽  
pp. 1-5 ◽  
Author(s):  
Wei-Ti Kuo ◽  
Hong-Yi Huang ◽  
Min-Ju Chou ◽  
Meng-Chao Wu ◽  
Yi-You Huang
Keyword(s):  
Gene Therapy ◽  
Surface Modification ◽  
Transfection Efficiency ◽  
Stable Complex ◽  
Gene Vector ◽  
Cell Toxicity ◽  
Gelatin Nanoparticles ◽  
Buffering Effect ◽  
High Transfection Efficiency ◽  
Pei Nanoparticles

A novel carrier on balancing the transfection efficiency and minimizing cytotoxicity was designed. Gelatin cross-linked with 1.8 kDa of PEI (GA-PEI 1.8 k) formed stable complex and resulted in high positiveζpotential (42.47 mV) and buffering effect. These nanoparticles with N/P ratio of 30 give high transfection efficiency  RLU/μg protein and cell viability (86.4%). These modified GA-PEI nanoparticles, with high transfection efficiency and low cell toxicity, can be a potential gene vector in gene therapy.

scholarly journals The National Gene Vector Biorepository: Eleven Years of Providing Resources to the Gene Therapy Community

2020 ◽  
Vol 31 (3-4) ◽  
pp. 145-150
Author(s):  
Kenneth Cornetta ◽  
Lorraine Matheson ◽  
Ryan Long ◽  
Lisa Duffy
Keyword(s):  
Gene Therapy ◽  
Gene Vector
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