Intracellular calcium: its movement during pentylenetetrazole-induced bursting activity

Science ◽  
1978 ◽  
Vol 200 (4343) ◽  
pp. 797-799 ◽  
Author(s):  
E Sugaya ◽  
M Onozuka
Keyword(s):  
Intracellular Calcium ◽  
Bursting Activity

Action of cyclic AMP on intracellular calcium concentration and bursting activity

1988 ◽  
Vol 2 (5) ◽  
pp. 317-322 ◽  
Author(s):  
Eiichi Sugaya ◽  
Hiroyasu Furuichi ◽  
Tamaki Takagi ◽  
Kagemasa Kajiwara ◽  
Junichi Komatsubara ◽  
...  
Keyword(s):  
Cyclic Amp ◽  
Intracellular Calcium ◽  
Calcium Concentration ◽  
Intracellular Calcium Concentration ◽  
Bursting Activity

Intracellular calcium distribution map and chemical shift of neurons examined by computer controlled electron probe X-ray microanalyser

1978 ◽  
Vol 36 (2) ◽  
pp. 126-127
Author(s):  
Minoru Onozuka ◽  
Eiichi Sugaya ◽  
Aiko Sugaya ◽  
Masayoshi Usami
Keyword(s):  
Chemical Shift ◽  
Intracellular Calcium ◽  
Electron Probe ◽  
Cellular Function ◽  
Distribution Map ◽  
X Ray ◽  
Calcium Distribution ◽  
Computer Controlled ◽  
Bursting Activity

The role of divalent cations, particularly of calcium, has gained increasing interest as a charge carrier and in processes such as regulation of enzymatic activities, in secretions of humoral transmitters and initiation of muscle contraction. The role of calcium has become very important in manifesting the bursting activity of neurons by various electrophysiological techniques, especially by voltage clamping. The distribution of calcium compared with the ultrastructure of nerve cells, however, has not been widely investigated. Analysis by the electron probe X-ray microanalyser(EPXMA) makes this type of research easier. To determine the relationship between calcium localization within the neuron and cellular function, we tried to make an intracellular calcium distribution map of the normal state and that during bursting activity by the computer controlled EPXMA. We also detected the chemical shift between the different states of cellular function caused by the intracellular calcium binding state.

Effect of phenytoin on intracellular calcium and intracellular protein changes during pentylenetetrazole-induced bursting activity in snail neurons

1985 ◽  
Vol 327 (1-2) ◽  
pp. 161-168 ◽  
Author(s):  
Eiichi Sugaya ◽  
Minoru Onozuka ◽  
Hiroyasu Furuichi ◽  
Kenichi Kishii ◽  
Shizuko Imai ◽  
...  
Keyword(s):  
Intracellular Calcium ◽  
Intracellular Protein ◽  
Snail Neurons ◽  
Bursting Activity

Intracellular calcium concentration during pentylenetetrazol-induced bursting activity in snail neurons

1987 ◽  
Vol 416 (1) ◽  
pp. 183-186 ◽  
Author(s):  
Eiichi Sugaya ◽  
Hiroyasu Furuichi ◽  
Tamaki Takagi ◽  
Kagemasa Kajiwara ◽  
Junichi Komatsubara
Keyword(s):  
Intracellular Calcium ◽  
Calcium Concentration ◽  
Intracellular Calcium Concentration ◽  
Snail Neurons ◽  
Bursting Activity

Ultra-Rapid Freezing of Isolated Skeletal Muscle Fibers

1977 ◽  
Vol 35 ◽  
pp. 576-577
Author(s):  
Joachim R. Sommer ◽  
Nancy R. Wallace
Keyword(s):  
Skeletal Muscle ◽  
Sarcoplasmic Reticulum ◽  
Granular Material ◽  
Nuclear Envelope ◽  
Intracellular Calcium ◽  
Ruthenium Red ◽  
Threshold Concentration ◽  
Rapid Freezing ◽  
Frog Skeletal Muscle ◽  
Electrical Isolation

After Howell (1) had shown that ruthenium red treatment of fixed frog skeletal muscle caused collapse of the intermediate cisternae of the sarcoplasmic reticulum (SR), forming a pentalaminate structure by obi iterating the SR lumen, we demonstrated that the phenomenon involves the entire SR including the nuclear envelope and that it also occurs after treatment with other cations, including calcium (2,3,4).From these observations we have formulated a hypothesis which states that intracellular calcium taken up by the SR at the end of contraction causes the M rete to collapse at a certain threshold concentration as the first step in a subsequent centrifugal zippering of the free SR toward the junctional SR (JSR). This would cause a) bulk transport of SR contents, such as calcium and granular material (4) into the JSR and, b) electrical isolation of the free SR from the JSR.

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