Growth hormone-releasing factor: direct effects on growth hormone, glucose, and behavior via the brain

Science ◽  
1984 ◽  
Vol 226 (4673) ◽  
pp. 464-466 ◽  
Author(s):  
G. Tannenbaum
Keyword(s):  
Growth Hormone ◽  
Direct Effects ◽  
Growth Hormone Releasing Factor ◽  
And Behavior ◽  
The Brain

scholarly journals Treatment with Growth Hormone (GH) Increased the Metabolic Activity of the Brain in an Elder Patient, Not GH-Deficient, Who Suffered Mild Cognitive Alterations and Had an ApoE 4/3 Genotype

2018 ◽  
Vol 19 (8) ◽  
pp. 2294 ◽  
Author(s):  
Jesús Devesa ◽  
Iria Núñez ◽  
Carlos Agra ◽  
Alejandro Bejarano ◽  
Pablo Devesa
Keyword(s):  
Growth Hormone ◽  
Metabolic Activity ◽  
Cerebral Metabolism ◽  
Verbal Learning ◽  
Pet Scan ◽  
Positive Effects ◽  
And Behavior ◽  
Knowledge Memory ◽  
The Brain ◽  
Cognitive Alterations

(1) Background: We analyzed, using PET-SCAN and cognitive tests, how growth hormone (GH) could act in the brain of an older woman, not deficient in GH, who showed mild cognitive alterations (MCI) and had a genotype of ApoE 4/3 and familial dyslipidemia. (2) Methods: After performing a first psychometric study (TAVEC verbal learning test), the metabolic activity of brain structures related to knowledge, memory, and behavior was analyzed using 18-F fluorodeoxyglucose PET-SCAN. The patient was then treated with GH (0.4 mg/day, subcutaneous) for three weeks and on the last day under this treatment, a new PET-SCAN was performed. One month after beginning treatment with GH, a new TAVEC test was performed. (3) Results: GH administration normalized the cognitive deficits observed in the first psychometric test and significantly (p < 0.025) increased the metabolic activity in practically all brain cortical areas, specifically in the left hippocampus and left amygdala, although not in the left parahippocampus. (4) Conclusions: This study demonstrates for the first time the positive effects of GH on cerebral metabolism in a patient without GH deficiency, recovering the function of affected areas related to knowledge, memory, and behavior in an elderly patient with MCI.

Effects of growth hormone-releasing factor in the brain

Science ◽  
1986 ◽  
Vol 232 (4755) ◽  
pp. 1271-1273 ◽  
Author(s):  
W. Wehrenberg ◽  
C. Ehlers
Keyword(s):  
Growth Hormone ◽  
Growth Hormone Releasing Factor ◽  
The Brain

Review of Self-regulation of the Brain and Behavior.

1985 ◽  
Vol 30 (12) ◽  
pp. 999-999
Author(s):  
Gerald S. Wasserman
Keyword(s):  
Self Regulation ◽  
Brain And Behavior ◽  
And Behavior ◽  
The Brain

Growth hormone releasing factor (GRF) infusion in patients with active acromegaly

1985 ◽  
Vol 110 (1_Suppla) ◽  
pp. S144-S145
Author(s):  
M. LOSA ◽  
J. SCHOPOHL ◽  
P. G. CHIODINI ◽  
A. LIUZZI ◽  
K. VON WERDER
Keyword(s):  
Growth Hormone ◽  
Growth Hormone Releasing Factor ◽  
Active Acromegaly

Synthetic pancreatic growth hormone-releasing factor (GRF-40) stimulates the secretion of the endocrine pancreas

Diabetes ◽  
1986 ◽  
Vol 35 (1) ◽  
pp. 119-123 ◽  
Author(s):  
K. Hermansen ◽  
A. M. Kappelgaard ◽  
J. Esmann ◽  
H. Orskov
Keyword(s):  
Growth Hormone ◽  
Endocrine Pancreas ◽  
Growth Hormone Releasing Factor ◽  
Pancreatic Growth

Effects of rhizobacteria on the biology and behavior of Plutella xylostella (Lepidoptera: Plutellidae)

2017 ◽  
Vol 43 (2) ◽  
pp. 195
Author(s):  
Robson Thomaz Thuler ◽  
Fernando Henrique Iost Filho ◽  
Hamilton César De Oliveira Charlo ◽  
Sergio Antônio De Bortoli
Keyword(s):  
Plutella Xylostella ◽  
Diamondback Moth ◽  
Insect Behavior ◽  
Control Treatment ◽  
Pupal Weight ◽  
Larval Feeding ◽  
Direct Effects ◽  
Plant Feeding ◽  
Kluyvera Ascorbata ◽  
And Behavior

Plant induced resistance is a tool for integrated pest management, aimed at increasing plant defense against stress, which is compatible with other techniques. Rhizobacteria act in the plant through metabolic changes and may have direct effects on plant-feeding insects. The objective of this study was to determine the effects of cabbage plants inoculated with rhizobacteria on the biology and behavior of diamondback moth, Plutella xylostella (Lepidoptera: Plutellidae). Cabbage seeds inoculated with 12 rhizobacteria strains were sowed in polystyrene trays and later transplanted into the greenhouse. The cabbage plants with sufficient size to support stress were then infested with diamondback moth caterpillars. Later, healthy leaves suffering injuries were collected and taken to the laboratory to feed P. xylostella second instar caterpillars that were evaluated for larval and pupal viability and duration, pupal weight, and sex ratio. The reduction of leaf area was then calculated as a measure of the amount of larval feeding. Non-preference for feeding and oviposition assays were also performed, by comparing the control treatment and plants inoculated with different rhizobacterial strains. Plants inoculated with the strains EN4 of Kluyvera ascorbata and HPF14 of Bacillus thuringiensis negatively affected the biological characteristics of P. xylostella when such traits were evaluated together, without directly affecting the insect behavior.

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