Solo actions of AIDS virus coat

Science ◽  
1987 ◽  
Vol 237 (4818) ◽  
pp. 971-973 ◽  
Author(s):  
D. Barnes
Keyword(s):  
Aids Virus ◽  
Virus Coat

AIDS virus coat activates T cells

Science ◽  
1988 ◽  
Vol 242 (4878) ◽  
pp. 515-515 ◽  
Author(s):  
D. Barnes
Keyword(s):  
T Cells ◽  
Aids Virus ◽  
Virus Coat

scholarly journals Nucleotide sequence of the potato leafroll virus coat protein gene

1989 ◽  
Vol 17 (4) ◽  
pp. 1768-1768 ◽  
Author(s):  
B. Prill ◽  
E. Maiss ◽  
U. Timpe ◽  
R. Casper
Keyword(s):  
Nucleotide Sequence ◽  
Coat Protein ◽  
Coat Protein Gene ◽  
Protein Gene ◽  
Potato Leafroll Virus ◽  
Virus Coat Protein ◽  
Virus Coat ◽  
Leafroll Virus

scholarly journals Molecular modeling and interaction between Arabidopsis sulfite oxidase and the GW motif of Turnip crinkle virus coat protein

Virology ◽  
2020 ◽  
Vol 551 ◽  
pp. 64-74
Author(s):  
Chao Wu ◽  
Srinivasaraghavan Kannan ◽  
Chandra S. Verma ◽  
Kunchithapadam Swaminathan ◽  
Sek-Man Wong
Keyword(s):  
Molecular Modeling ◽  
Coat Protein ◽  
Sulfite Oxidase ◽  
Turnip Crinkle Virus ◽  
Virus Coat Protein ◽  
Virus Coat

Protein-Embedded Metalloporphyrin Arrays Templated by Circularly Permuted Tobacco Mosaic Virus Coat Proteins

ACS Nano ◽  
2020 ◽  
Author(s):  
Jing Dai ◽  
Gavin J. Knott ◽  
Wen Fu ◽  
Tiffany W. Lin ◽  
Ariel L. Furst ◽  
...  
Keyword(s):  
Tobacco Mosaic Virus ◽  
Mosaic Virus ◽  
Coat Proteins ◽  
Virus Coat

Robert C. Gallo—Discoverer of the AIDS Virus

2001 ◽  
Vol 76 (10) ◽  
pp. 968
Author(s):  
Marc A. Shampo ◽  
Robert A. Kyle
Keyword(s):  
Aids Virus

Expression of the T4 molecule (AIDS virus receptor) by human brain-derived cells

FEBS Letters ◽  
1987 ◽  
Vol 213 (1) ◽  
pp. 133-137 ◽  
Author(s):  
Stephen Dewhurst ◽  
Mario Stevenson ◽  
David J. Volsky
Keyword(s):  
Human Brain ◽  
Virus Receptor ◽  
Aids Virus

Conjugation of an antibody Fv fragment to a virus coat protein: cell-specific targeting of recombinant polyoma-virus-like particles

2001 ◽  
Vol 356 (3) ◽  
pp. 867-873 ◽  
Author(s):  
Kay STUBENRAUCH ◽  
Stefan GLEITER ◽  
Ulrich BRINKMANN ◽  
Rainer RUDOLPH ◽  
Hauke LILIE
Keyword(s):  
Coat Protein ◽  
Mammalian Cells ◽  
Recombinant Antibody ◽  
Specific Antigen ◽  
Antibody Fragment ◽  
Fusion Peptides ◽  
Virus Like Particles ◽  
Vector Systems ◽  
Virus Coat

The development of cell-type-specific delivery systems is highly desirable for gene-therapeutic applications. Current virus-based vector systems show broad cell specificity, which results in the need to restrict the natural tropism of these viral systems. Here we demonstrate that tumour-cell-specific virus-like particles can be functionally assembled in vitro from recombinant viral coat protein expressed in Escherichia coli. The insertion of a negatively charged peptide in the HI loop of polyoma VP1 interferes with the binding of VP1 to the natural recognition site on mammalian cells and also serves as an adapter for the coupling of antibody fragments that contain complementary charged fusion peptides. A recombinant antibody fragment of the tumour-specific anti-(Lewis Y) antibody B3 could be coupled to the mutant VP1 by engineered polyionic peptides and an additional disulphide bond. With this system an entirely recombinant cell-specific delivery system assembled in vitro could be generated that transfers genes preferentially to cells presenting the tumour-specific antigen on the cell surface.

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