Genomic organization and deduced amino acid sequence of a putative sodium channel gene in Drosophila

Science ◽  
1987 ◽  
Vol 237 (4816) ◽  
pp. 744-749 ◽  
Author(s):  
L Salkoff ◽  
A Butler ◽  
A Wei ◽  
N Scavarda ◽  
K Giffen ◽  
...  
Keyword(s):  
Amino Acid ◽  
Amino Acid Sequence ◽  
Sodium Channel ◽  
Genomic Organization ◽  
Channel Gene ◽  
Sodium Channel Gene

A novel amino acid substitution in the para-sodium channel gene in Rhipicephalus microplus (Acari: Ixodidae) associated with knockdown resistance

2010 ◽  
Vol 52 (4) ◽  
pp. 377-382 ◽  
Author(s):  
Marcelino Aguirre ◽  
Adriana E. Flores ◽  
Genoveva Álvarez ◽  
Alberto Molina ◽  
Iram Rodriguez ◽  
...  
Keyword(s):  
Amino Acid ◽  
Sodium Channel ◽  
Amino Acid Substitution ◽  
Rhipicephalus Microplus ◽  
Knockdown Resistance ◽  
Channel Gene ◽  
Sodium Channel Gene

Genomic Organization of the Human Skeletal Muscle Sodium Channel Gene

Genomics ◽  
1993 ◽  
Vol 15 (3) ◽  
pp. 598-606 ◽  
Author(s):  
Alfred L. George ◽  
Geeta S. Iyer ◽  
Robert Kleinfield ◽  
Roland G. Kallen ◽  
Robert L. Barchi
Keyword(s):  
Skeletal Muscle ◽  
Sodium Channel ◽  
Human Skeletal Muscle ◽  
Genomic Organization ◽  
Channel Gene ◽  
Sodium Channel Gene

scholarly journals Permethrin Resistance in Aedes aegypti Affects Aspects of Vectorial Capacity

Insects ◽  
2021 ◽  
Vol 12 (1) ◽  
pp. 71
Author(s):  
Tse-Yu Chen ◽  
Chelsea T. Smartt ◽  
Dongyoung Shin
Keyword(s):  
Aedes Aegypti ◽  
Sodium Channel ◽  
Mosquito Control ◽  
Vector Competence ◽  
Vectorial Capacity ◽  
Parental Population ◽  
Control Programs ◽  
Channel Gene ◽  
Sodium Channel Gene ◽  
Specific Pcr

Aedes aegypti, as one of the vectors transmitting several arboviruses, is the main target in mosquito control programs. Permethrin is used to control mosquitoes and Aedes aegypti get exposed due to its overuse and are now resistant. The increasing percentage of permethrin resistant Aedes aegypti has become an important issue around the world and the potential influence on vectorial capacity needs to be studied. Here we selected a permethrin resistant (p-s) Aedes aegypti population from a wild Florida population and confirmed the resistance ratio to its parental population. We used allele-specific PCR genotyping of the V1016I and F1534C sites in the sodium channel gene to map mutations responsible for the resistance. Two important factors, survival rate and vector competence, that impact vectorial capacity were checked. Results indicated the p-s population had 20 times more resistance to permethrin based on LD50 compared to the parental population. In the genotyping study, the p-s population had more homozygous mutations in both mutant sites of the sodium channel gene. The p-s adults survived longer and had a higher dissemination rate for dengue virus than the parental population. These results suggest that highly permethrin resistant Aedes aegypti populations might affect the vectorial capacity, moreover, resistance increased the survival time and vector competence, which should be of concern in areas where permethrin is applied.

scholarly journals Polymorphisms in voltage-gated sodium channel gene and susceptibility of Aedes albopictus to insecticides in three districts of northern West Bengal, India

2018 ◽  
Vol 12 (1) ◽  
pp. e0006192 ◽  
Author(s):  
Moytrey Chatterjee ◽  
Sudeep Ballav ◽  
Ardhendu K. Maji ◽  
Nandita Basu ◽  
Biplab Chandra Sarkar ◽  
...  
Keyword(s):  
Sodium Channel ◽  
Aedes Albopictus ◽  
West Bengal ◽  
Voltage Gated Sodium Channel ◽  
Voltage Gated ◽  
Channel Gene ◽  
Sodium Channel Gene

scholarly journals Association between Three Mutations, F1565C, V1023G and S996P, in the Voltage-Sensitive Sodium Channel Gene and Knockdown Resistance in Aedes aegypti from Yogyakarta, Indonesia

Insects ◽  
2015 ◽  
Vol 6 (3) ◽  
pp. 658-685 ◽  
Author(s):  
Juli Wuliandari ◽  
Siu Lee ◽  
Vanessa White ◽  
Warsito Tantowijoyo ◽  
Ary Hoffmann ◽  
...  
Keyword(s):  
Aedes Aegypti ◽  
Sodium Channel ◽  
Knockdown Resistance ◽  
Channel Gene ◽  
Sodium Channel Gene

The genomic structure of the human skeletal muscle sodium channel gene

1992 ◽  
Vol 1 (7) ◽  
pp. 521-527 ◽  
Author(s):  
Andrea I.McClatchey ◽  
Carol S.Lin ◽  
Jianzhou Wang ◽  
Eric P.Hoffman ◽  
Cecilia Rojas ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Sodium Channel ◽  
Human Skeletal Muscle ◽  
Genomic Structure ◽  
Channel Gene ◽  
Sodium Channel Gene

132 TuNaII: A putative sodium channel gene specifically expressed in ascidian motoneuron lineage

1996 ◽  
Vol 25 ◽  
pp. S27
Author(s):  
Yasushi Okamura ◽  
Hitoshi Nagahora ◽  
Toshiaki Okada
Keyword(s):  
Sodium Channel ◽  
Channel Gene ◽  
Sodium Channel Gene
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