Primary sequence information from intact proteins by electrospray ionization tandem mass spectrometry

Science ◽  
1990 ◽  
Vol 248 (4952) ◽  
pp. 201-204 ◽  
Author(s):  
J. Loo ◽  
C. Edmonds ◽  
R. Smith
Keyword(s):  
Mass Spectrometry ◽  
Tandem Mass Spectrometry ◽  
Electrospray Ionization ◽  
Sequence Information ◽  
Tandem Mass ◽  
Primary Sequence ◽  
Intact Proteins ◽  
Ionization Tandem Mass Spectrometry

Direct sequencing of a disulfide-linked peptide with electrospray ionization tandem mass spectrometry

The Analyst ◽  
2015 ◽  
Vol 140 (8) ◽  
pp. 2623-2627 ◽  
Author(s):  
Gongyu Li ◽  
Jiying Pei ◽  
Yue Yin ◽  
Guangming Huang
Keyword(s):  
Mass Spectrometry ◽  
Tandem Mass Spectrometry ◽  
Corona Discharge ◽  
Electrospray Ionization ◽  
Disulfide Bonds ◽  
Direct Sequencing ◽  
Peptide Sequencing ◽  
Tandem Mass ◽  
Esi Ms ◽  
Ionization Tandem Mass Spectrometry

Enhanced corona discharge was employed for in-spray dissociation of disulfide bonds, facilitating disulfide-containing peptide sequencing with ESI-MS/MS.

Sign in / Sign up

Export Citation Format

Share Document