Selecting T cell receptors with high affinity for self-MHC by decreasing the contribution of CD8

Science ◽  
1992 ◽  
Vol 258 (5083) ◽  
pp. 815-818 ◽  
Author(s):  
L. Sherman ◽  
S. Hesse ◽  
M. Irwin ◽  
D La Face ◽  
P Peterson
Keyword(s):  
T Cell ◽  
T Cell Receptors ◽  
Cell Receptors ◽  
High Affinity

Engineering high affinity, soluble T cell receptors for the treatment of cancer

2018 ◽  
Vol 92 ◽  
pp. S15-S16
Author(s):  
L. Holt ◽  
N. Liddy ◽  
G. Bossi ◽  
J. Harper ◽  
J. Dukes ◽  
...  
Keyword(s):  
T Cell ◽  
T Cell Receptors ◽  
Cell Receptors ◽  
High Affinity

Characterization of T Cell Receptors Engineered for High Affinity Against Toxic Shock Syndrome Toxin-1

2005 ◽  
Vol 353 (2) ◽  
pp. 308-321 ◽  
Author(s):  
Rebecca A. Buonpane ◽  
Beenu Moza ◽  
Eric J. Sundberg ◽  
David M. Kranz
Keyword(s):  
T Cell ◽  
T Cell Receptors ◽  
Toxic Shock Syndrome ◽  
Toxic Shock ◽  
Cell Receptors ◽  
High Affinity ◽  
Toxic Shock Syndrome Toxin

High-affinity, Peptide-specific T Cell Receptors can be Generated by Mutations in CDR1, CDR2 or CDR3

2005 ◽  
Vol 346 (1) ◽  
pp. 223-239 ◽  
Author(s):  
Lukasz K. Chlewicki ◽  
Phillip D. Holler ◽  
Bridget C. Monti ◽  
Matthew R. Clutter ◽  
David M. Kranz
Keyword(s):  
T Cell ◽  
T Cell Receptors ◽  
Cell Receptors ◽  
High Affinity ◽  
Affinity Peptide

scholarly journals Targeting naturally occurring epitope variants of hepatitis C virus with high-affinity T-cell receptors

2017 ◽  
Vol 98 (3) ◽  
pp. 374-384 ◽  
Author(s):  
Huajun Zhang ◽  
Jianbing Zhang ◽  
Lei Chen ◽  
Zhiming Weng ◽  
Ye Tian ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
T Cell ◽  
T Cell Receptors ◽  
Cell Receptors ◽  
High Affinity ◽  
Naturally Occurring

High Affinity T Cell Receptors as Therapeutic Agents

2007 ◽  
Vol 123 ◽  
pp. S7
Author(s):  
Rebecca Ashfield ◽  
Deborah Sutton ◽  
Giovanna Bossi ◽  
Joanna Brewer ◽  
Marco Purbhoo ◽  
...  
Keyword(s):  
T Cell ◽  
T Cell Receptors ◽  
Therapeutic Agents ◽  
Cell Receptors ◽  
High Affinity

scholarly journals Different Thermodynamic Binding Mechanisms and Peptide Fine Specificities Associated with a Panel of Structurally Similar High-Affinity T Cell Receptors†‡

Biochemistry ◽  
2008 ◽  
Vol 47 (47) ◽  
pp. 12398-12408 ◽  
Author(s):  
Lindsay L. Jones ◽  
Leremy A. Colf ◽  
Alexander J. Bankovich ◽  
Jennifer D. Stone ◽  
Yi-Gui Gao ◽  
...  
Keyword(s):  
T Cell ◽  
T Cell Receptors ◽  
Cell Receptors ◽  
High Affinity ◽  
Binding Mechanisms
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