Role of Intermolecular Forces in Defining Material Properties of Protein Nanofibrils

Science ◽  
2007 ◽  
Vol 318 (5858) ◽  
pp. 1900-1903 ◽  
Author(s):  
T. P. Knowles ◽  
A. W. Fitzpatrick ◽  
S. Meehan ◽  
H. R. Mott ◽  
M. Vendruscolo ◽  
...  
Keyword(s):  
Material Properties ◽  
Intermolecular Forces

The role of gas flow distributions on CO2 mineralization within monolithic cemented composites: coupled CFD-factorial design approach

2021 ◽  
Author(s):  
Iman Mehdipour ◽  
Gabriel Falzone ◽  
Dale Prentice ◽  
Narayanan Neithalath ◽  
Dante Simonetti ◽  
...  
Keyword(s):  
Spatial Distribution ◽  
Factorial Design ◽  
Material Properties ◽  
Gas Flow ◽  
Design Approach ◽  
Processing Conditions ◽  
Gas Processing ◽  
Co2 Mineralization

Optimizing the spatial distribution of contacting gas and the gas processing conditions enhances CO2 mineralization reactions and material properties of carbonate-cementitious monoliths.

scholarly journals Influence of the Electrolyte Salt Concentration on DNA Detection with Graphene Transistors

Biosensors ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 24
Author(s):  
Agnes Purwidyantri ◽  
Telma Domingues ◽  
Jérôme Borme ◽  
Joana Rafaela Guerreiro ◽  
Andrey Ipatov ◽  
...  
Keyword(s):  
Phosphate Buffer ◽  
Species Interactions ◽  
Field Effect ◽  
Field Effect Transistors ◽  
Limit Of Detection ◽  
Debye Length ◽  
Intermolecular Forces ◽  
Single Layer Graphene ◽  
Dna Adsorption

Liquid-gated Graphene Field-Effect Transistors (GFET) are ultrasensitive bio-detection platforms carrying out the graphene’s exceptional intrinsic functionalities. Buffer and dilution factor are prevalent strategies towards the optimum performance of the GFETs. However, beyond the Debye length (λD), the role of the graphene-electrolytes’ ionic species interactions on the DNA behavior at the nanoscale interface is complicated. We studied the characteristics of the GFETs under different ionic strength, pH, and electrolyte type, e.g., phosphate buffer (PB), and phosphate buffer saline (PBS), in an automatic portable built-in system. The electrostatic gating and charge transfer phenomena were inferred from the field-effect measurements of the Dirac point position in single-layer graphene (SLG) transistors transfer curves. Results denote that λD is not the main factor governing the effective nanoscale screening environment. We observed that the longer λD was not the determining characteristic for sensitivity increment and limit of detection (LoD) as demonstrated by different types and ionic strengths of measuring buffers. In the DNA hybridization study, our findings show the role of the additional salts present in PBS, as compared to PB, in increasing graphene electron mobility, electrostatic shielding, intermolecular forces and DNA adsorption kinetics leading to an improved sensitivity.

The Role of Topology and Tissue Mechanics in Remora Attachment

2014 ◽  
Vol 1648 ◽  
Author(s):  
Michael Culler ◽  
Keri A. Ledford ◽  
Jason H. Nadler
Keyword(s):  
Finite Element ◽  
Material Properties ◽  
Tissue Mechanics ◽  
Unit Cell ◽  
Surface Topology ◽  
Finite Element Models ◽  
Cell Geometry ◽  
Critical Step ◽  
Tissue Material

ABSTRACTRemora fish are capable of fast, reversible and reliable adhesion to a wide variety of both natural and artificial marine hosts through a uniquely evolved dorsal pad. This adhesion is partially attributed to suction, which requires a robust seal between the pad interior and the ambient environment. Understanding the behavior of remora adhesion based on measurable surface parameters and material properties is a critical step when creating artificial, bio-inspired devices. In this work, structural and fluid finite element models (FEM) based on a simplified “unit cell” geometry were developed to predict the behavior of the seal with respect to host/remora surface topology and tissue material properties.

CERAMICS BASED ON ORGANOSILICON POLYMERS-PRECURSORS: MICROSTRUCTURE AND PROPERTIES (review). Part 2

2021 ◽  
pp. 22-32
Author(s):  
A.M. Shestakov ◽  
Keyword(s):  
Electron Microscopy ◽  
Nmr Spectroscopy ◽  
Material Properties ◽  
Structural Organization ◽  
Ceramic Materials ◽  
Special Role ◽  
Correct Interpretation ◽  
Instrumental Methods ◽  
Organosilicon Polymers

Shows the scientific approaches of various authors to the study of the microstructure of ceramics, the purpose of which is to elucidate its structural organization at the micro- and nanoscale, as well as the influence of the microstructure on the complex of material properties. Various instrumental methods for studying ceramics (NMR spectroscopy, electron microscopy, х-ray structural analysis, etc.) are considered, the permissible capabilities of research methods and analysis of the results obtained with their correct interpretation are shown. The special role of theoretical modeling in understanding the structure of the considered ceramic materials is noted.

Role of drug substance material properties in the processibility and performance of a wet granulated product

2009 ◽  
Vol 374 (1-2) ◽  
pp. 96-105 ◽  
Author(s):  
Chandra Vemavarapu ◽  
Madhu Surapaneni ◽  
Munir Hussain ◽  
Sherif Badawy
Keyword(s):  
Material Properties ◽  
Drug Substance ◽  
And Performance

Modeling the Inflation Response of C57BL/6 Mouse Sclera

2011 ◽  
Author(s):  
Kristin M. Myers ◽  
Thao D. Nguyen
Keyword(s):  
Material Properties ◽  
Soft Tissues ◽  
Ganglion Cells ◽  
The United States ◽  
Small Rodent ◽  
Tissue Samples ◽  
Tissue Microstructure ◽  
Material Parameters ◽  
Meaningful Material

Small rodent models have become increasingly useful to investigate how the mechanical properties of soft tissues may influence disease development. These animal models allow access to aged, diseased, or genetically-altered tissue samples, and through comparisons with wild-type or normal tissue it can be explored how each of these variables influence tissue function. The challenges to deriving meaningful material parameters for these small tissue samples include designing physiologically-relevant mechanical testing protocols and interpreting the experimental load-displacement data in an appropriate constitutive framework to quantify material parameters. This study was motivated by determining the possible role of scleral material properties in the development of glaucomatous damage to the retinal ganglion cells (RGC). Glaucoma is one of the leading causes of blindness in the United States and in the world with an estimate of 60 million people affected by this year [1]. Through exploring mouse models, the overall goal of our work is to determine the role of scleral material properties and scleral tissue microstructure in the pathogenesis of glaucoma.

Inflammation and biomaterials: role of the immune response in bone regeneration by inorganic scaffolds

2020 ◽  
Vol 8 (41) ◽  
pp. 9404-9427 ◽  
Author(s):  
Joanna M. Sadowska ◽  
Maria-Pau Ginebra
Keyword(s):  
Immune Response ◽  
Immune System ◽  
Bone Regeneration ◽  
Material Properties ◽  
Specific Material

The design of inorganic scaffolds able to instruct the immune system, eliciting adequate feedback by tuning specific material properties, has become an emerging field of research.

scholarly journals The role of material properties for the mechanical adaptation at branch junctions

Trees ◽  
2008 ◽  
Vol 23 (3) ◽  
pp. 605-610 ◽  
Author(s):  
Karin Jungnikl ◽  
Jürgen Goebbels ◽  
Ingo Burgert ◽  
Peter Fratzl
Keyword(s):  
Material Properties ◽  
Mechanical Adaptation
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