Domain Architecture of Pyruvate Carboxylase, a Biotin-Dependent Multifunctional Enzyme

Science ◽  
2007 ◽  
Vol 317 (5841) ◽  
pp. 1076-1079 ◽  
Author(s):  
M. St. Maurice ◽  
L. Reinhardt ◽  
K. H. Surinya ◽  
P. V. Attwood ◽  
J. C. Wallace ◽  
...  
Keyword(s):  
Pyruvate Carboxylase ◽  
Domain Architecture ◽  
Multifunctional Enzyme

Plant carotenoid cleavage oxygenases: structure–function relationships and role in development and metabolism

2019 ◽  
Vol 19 (1) ◽  
pp. 1-9 ◽  
Author(s):  
Manoj Kumar Dhar ◽  
Sonal Mishra ◽  
Archana Bhat ◽  
Sudha Chib ◽  
Sanjana Kaul
Keyword(s):  
Higher Plants ◽  
Domain Architecture ◽  
Heme Iron ◽  
Critical Assessment ◽  
Protein Family ◽  
Regulatory Mechanisms ◽  
Non Heme Iron ◽  
Functional Aspects ◽  
Functional Understanding ◽  
Signal Production

Abstract A plant communicates within itself and with the outside world by deploying an array of agents that include several attractants by virtue of their color and smell. In this category, the contribution of ‘carotenoids and apocarotenoids’ is very significant. Apocarotenoids, the carotenoid-derived compounds, show wide representation among organisms. Their biosynthesis occurs by oxidative cleavage of carotenoids, a high-value reaction, mediated by carotenoid cleavage oxygenases or carotenoid cleavage dioxygenases (CCDs)—a family of non-heme iron enzymes. Structurally, this protein family displays wide diversity but is limited in its distribution among plants. Functionally, this protein family has been recognized to offer a role in phytohormones, volatiles and signal production. Further, their wide presence and clade-specific functional disparity demands a comprehensive account. This review focuses on the critical assessment of CCDs of higher plants, describing recent progress in their functional aspects and regulatory mechanisms, domain architecture, classification and localization. The work also highlights the relevant discussion for further exploration of this multi-prospective protein family for the betterment of its functional understanding and improvement of crops.

MRI, Clinical, and Biochemical Features of Partial Pyruvate Carboxylase Deficiency

1994 ◽  
Vol 9 (4) ◽  
pp. 436-439 ◽  
Author(s):  
Joseph J. Higgins ◽  
Allen M. Glasgow ◽  
Marilyn Lusk ◽  
Douglas S. Kerr
Keyword(s):  
Pyruvate Carboxylase ◽  
Pyruvate Carboxylase Deficiency ◽  
Biochemical Features

scholarly journals Pyruvate Carboxylase

1967 ◽  
Vol 242 (8) ◽  
pp. 1723-1735 ◽  
Author(s):  
Michael C. Scrutton ◽  
Merton F. Utter
Keyword(s):  
Pyruvate Carboxylase

scholarly journals Rat Liver Pyruvate Carboxylase

1971 ◽  
Vol 246 (11) ◽  
pp. 3569-3578 ◽  
Author(s):  
W.R. McClure ◽  
Henry A. Lardy ◽  
Helmut P. Kneifel
Keyword(s):  
Rat Liver ◽  
Pyruvate Carboxylase
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