Crystal Structure of the Low-pH Form of the Vesicular Stomatitis Virus Glycoprotein G

Science ◽  
2006 ◽  
Vol 313 (5784) ◽  
pp. 187-191 ◽  
Author(s):  
S. Roche
Keyword(s):  
Crystal Structure ◽  
Vesicular Stomatitis Virus ◽  
Low Ph ◽  
Vesicular Stomatitis Virus Glycoprotein ◽  
Virus Glycoprotein ◽  
Glycoprotein G ◽  
Vesicular Stomatitis

scholarly journals Construction and expression of a recombinant DNA gene encoding a polyomavirus middle-size tumor antigen with the carboxyl terminus of the vesicular stomatitis virus glycoprotein G.

1984 ◽  
Vol 4 (2) ◽  
pp. 282-289 ◽  
Author(s):  
D Templeton ◽  
A Voronova ◽  
W Eckhart
Keyword(s):  
Amino Acids ◽  
Vesicular Stomatitis Virus ◽  
Tumor Antigen ◽  
Protein Kinase Activity ◽  
Hybrid Protein ◽  
Vesicular Stomatitis Virus Glycoprotein ◽  
Hybrid Gene ◽  
Virus Glycoprotein ◽  
Glycoprotein G ◽  
Vesicular Stomatitis

We constructed a molecular clone encoding the N-terminal 379 amino acids of the polyomavirus middle-size tumor antigen, followed by the C-terminal 60 amino acids of the vesicular stomatitis virus glycoprotein G. This hybrid gene contained the coding region for the C-terminal hydrophobic membrane-spanning domain of the G protein in place of the C-terminal hydrophobic domain of the middle-size tumor antigen. The hybrid gene was expressed in COS-1 cells under the control of the simian virus 40 late promoter. The hybrid protein was located in cell membranes and was associated with a tyrosine-specific protein kinase activity, as was the middle-size tumor antigen. Plasmids encoding the hybrid protein failed to transform mouse NIH 3T3 or rat F2408 cells.

Structure of the Prefusion Form of the Vesicular Stomatitis Virus Glycoprotein G

Science ◽  
2007 ◽  
Vol 315 (5813) ◽  
pp. 843-848 ◽  
Author(s):  
S. Roche ◽  
F. A. Rey ◽  
Y. Gaudin ◽  
S. Bressanelli
Keyword(s):  
Vesicular Stomatitis Virus ◽  
Vesicular Stomatitis Virus Glycoprotein ◽  
Virus Glycoprotein ◽  
Glycoprotein G ◽  
Vesicular Stomatitis
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