Nod2 Mutation in Crohn's Disease Potentiates NF- B Activity and IL-1  Processing

S. Maeda

doi:10.1126/science.1103685

Nod2 Mutation in Crohn's Disease Potentiates NF- B Activity and IL-1 Processing

Science ◽

10.1126/science.1103685 ◽

2005 ◽

Vol 307 (5710) ◽

pp. 734-738 ◽

Cited By ~ 553

Author(s):

S. Maeda

Keyword(s):

Crohn’S Disease ◽

Crohn's Disease ◽

Nod2 Mutation

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Faculty Opinions recommendation of Reduced alpha-defensin expression is associated with inflammation and not NOD2 mutation status in ileal Crohn's disease.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1116137.617644 ◽

2009 ◽

Author(s):

Satish Keshav

Keyword(s):

Crohn’S Disease ◽

Crohn's Disease ◽

Mutation Status ◽

Nod2 Mutation

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Faculty Opinions recommendation of Reduced alpha-defensin expression is associated with inflammation and not NOD2 mutation status in ileal Crohn's disease.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1116137.572120 ◽

2008 ◽

Author(s):

Paul Pavli

Keyword(s):

Crohn’S Disease ◽

Crohn's Disease ◽

Mutation Status ◽

Nod2 Mutation

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Reduced -defensin expression is associated with inflammation and not NOD2 mutation status in ileal Crohn's disease

Gut ◽

10.1136/gut.2007.142588 ◽

2008 ◽

Vol 57 (7) ◽

pp. 903-910 ◽

Cited By ~ 168

Author(s):

L A Simms ◽

J D Doecke ◽

M D Walsh ◽

N Huang ◽

E V Fowler ◽

...

Keyword(s):

Crohn’S Disease ◽

Crohn's Disease ◽

Mutation Status ◽

Nod2 Mutation

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Faculty Opinions recommendation of Nod2 mutation in Crohn's disease potentiates NF-kappaB activity and IL-1beta processing.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1023798.284704 ◽

2005 ◽

Author(s):

Xiaojing Ma

Keyword(s):

Crohn’S Disease ◽

Crohn's Disease ◽

Nod2 Mutation ◽

Nf Kappab

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Development of a uniform, very aggressive disease phenotype in all homozygous carriers of the NOD2 mutation p.Leu1007fsX1008 with Crohn’s disease and active smoking status resulting in ileal stenosis requiring surgery

PLoS ONE ◽

10.1371/journal.pone.0236421 ◽

2020 ◽

Vol 15 (7) ◽

pp. e0236421

Author(s):

Fabian Schnitzler ◽

Matthias Friedrich ◽

Marianne Angelberger ◽

Julia Diegelmann ◽

Johannes Stallhofer ◽

...

Keyword(s):

Crohn’S Disease ◽

Crohn's Disease ◽

Smoking Status ◽

Active Smoking ◽

Disease Phenotype ◽

Nod2 Mutation ◽

Aggressive Disease

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Faculty Opinions recommendation of Nod2 mutation in Crohn's disease potentiates NF-kappaB activity and IL-1beta processing.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1023798.286787 ◽

2005 ◽

Author(s):

Betty Tsao

Keyword(s):

Crohn’S Disease ◽

Crohn's Disease ◽

Nod2 Mutation ◽

Nf Kappab

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Faculty Opinions recommendation of Nod2 mutation in Crohn's disease potentiates NF-kappaB activity and IL-1beta processing.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1023798.284807 ◽

2005 ◽

Author(s):

Sankar Ghosh

Keyword(s):

Crohn’S Disease ◽

Crohn's Disease ◽

Nod2 Mutation ◽

Nf Kappab

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Faculty Opinions recommendation of Nod2 mutation in Crohn's disease potentiates NF-kappaB activity and IL-1beta processing.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1023798.283697 ◽

2005 ◽

Author(s):

Torben Lund

Keyword(s):

Crohn’S Disease ◽

Crohn's Disease ◽

Nod2 Mutation ◽

Nf Kappab

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Faculty Opinions recommendation of A Crohn's disease-associated NOD2 mutation suppresses transcription of human IL10 by inhibiting activity of the nuclear ribonucleoprotein hnRNP-A1.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1159080.620651 ◽

2009 ◽

Author(s):

Nicola Jones

Keyword(s):

Crohn’S Disease ◽

Crohn's Disease ◽

Inhibiting Activity ◽

Hnrnp A1 ◽

Nod2 Mutation ◽

Nuclear Ribonucleoprotein ◽

Human Il10

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Faculty Opinions recommendation of A Crohn's disease-associated NOD2 mutation suppresses transcription of human IL10 by inhibiting activity of the nuclear ribonucleoprotein hnRNP-A1.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1159080.619376 ◽

2009 ◽

Author(s):

Nadine Cerf-Bensussan

Keyword(s):

Crohn’S Disease ◽

Crohn's Disease ◽

Inhibiting Activity ◽

Hnrnp A1 ◽

Nod2 Mutation ◽

Nuclear Ribonucleoprotein ◽

Human Il10

Download Full-text