scholarly journals Xenogeneic skin transplantation promotes angiogenesis and tissue regeneration through activated Trem2 + macrophages

2021 ◽  
Vol 7 (49) ◽  
Author(s):  
Dominic Henn ◽  
Kellen Chen ◽  
Tobias Fehlmann ◽  
Artem A. Trotsyuk ◽  
Dharshan Sivaraj ◽  
...  
Keyword(s):  
Tissue Regeneration ◽  
Skin Transplantation

Decellularized bone extracellular matrix in skeletal tissue engineering

2020 ◽  
Vol 48 (3) ◽  
pp. 755-764
Author(s):  
Benjamin B. Rothrauff ◽  
Rocky S. Tuan
Keyword(s):  
Tissue Engineering ◽  
Bone Regeneration ◽  
Tissue Regeneration ◽  
Animal Studies ◽  
Tumor Resection ◽  
Regenerative Capacity ◽  
Skeletal Tissue ◽  
Large Bone

Bone possesses an intrinsic regenerative capacity, which can be compromised by aging, disease, trauma, and iatrogenesis (e.g. tumor resection, pharmacological). At present, autografts and allografts are the principal biological treatments available to replace large bone segments, but both entail several limitations that reduce wider use and consistent success. The use of decellularized extracellular matrices (ECM), often derived from xenogeneic sources, has been shown to favorably influence the immune response to injury and promote site-appropriate tissue regeneration. Decellularized bone ECM (dbECM), utilized in several forms — whole organ, particles, hydrogels — has shown promise in both in vitro and in vivo animal studies to promote osteogenic differentiation of stem/progenitor cells and enhance bone regeneration. However, dbECM has yet to be investigated in clinical studies, which are needed to determine the relative efficacy of this emerging biomaterial as compared with established treatments. This mini-review highlights the recent exploration of dbECM as a biomaterial for skeletal tissue engineering and considers modifications on its future use to more consistently promote bone regeneration.

192: Tubularized Urethral Replacement: What is the Maximum Distance for Normal Tissue Regeneration?

2004 ◽  
Vol 171 (4S) ◽  
pp. 51-51
Author(s):  
Roger E. De Filippo ◽  
Hans G. Pohl ◽  
James J. Yoo ◽  
Anthony Atala
Keyword(s):  
Tissue Regeneration ◽  
Normal Tissue ◽  
Maximum Distance

Microvascular integrity plays a role in graft survival after skin transplantation

2014 ◽  
Vol 62 (S 01) ◽  
Author(s):  
C. Heim ◽  
B. Motsch ◽  
N. Koch ◽  
M. Ramsperger-Gleixner ◽  
M. Weyand ◽  
...  
Keyword(s):  
Graft Survival ◽  
Skin Transplantation

Metalloproteinases as mediators of tissue regeneration in the peripheral nerve: an important role for metalloproteinase-2

2007 ◽  
Vol 34 (S 2) ◽  
Author(s):  
A Köhne ◽  
HC Lehmann ◽  
O Kiehl ◽  
G Meyer zu Hörste ◽  
HP Hartung ◽  
...  
Keyword(s):  
Peripheral Nerve ◽  
Tissue Regeneration

AUTO-SKIN TRANSPLANTATION IN DOGS

2012 ◽  
Vol 11 (2) ◽  
pp. 113-119 ◽  
Author(s):  
Moyaser G. Thannoon ◽  
Sahar M. Ibrahim and Muneer S. Al-Badrany
Keyword(s):  
Skin Transplantation

EZH2 regulates responses of endothelial cells under hypoxia and during tissue regeneration following limb ischemia

2014 ◽  
Author(s):  
Tijana Mitic ◽  
Micol Marchetti ◽  
Marco Meloni ◽  
Andrea Caporali ◽  
Costanza Emanueli
Keyword(s):  
Endothelial Cells ◽  
Tissue Regeneration ◽  
Limb Ischemia
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