scholarly journals Ancient genomes reveal complex patterns of population movement, interaction, and replacement in sub-Saharan Africa

2020 ◽  
Vol 6 (24) ◽  
pp. eaaz0183 ◽  
Author(s):  
Ke Wang ◽  
Steven Goldstein ◽  
Madeleine Bleasdale ◽  
Bernard Clist ◽  
Koen Bostoen ◽  
...  
Keyword(s):  
Southern Africa ◽  
Sub Saharan Africa ◽  
The Past ◽  
Genome Wide ◽  
Movement Interaction ◽  
Genome Wide Data ◽  
Sub Saharan ◽  
Population Interactions ◽  
Eastern And Southern Africa ◽  
Complex Trajectories

Africa hosts the greatest human genetic diversity globally, but legacies of ancient population interactions and dispersals across the continent remain understudied. Here, we report genome-wide data from 20 ancient sub-Saharan African individuals, including the first reported ancient DNA from the DRC, Uganda, and Botswana. These data demonstrate the contraction of diverse, once contiguous hunter-gatherer populations, and suggest the resistance to interaction with incoming pastoralists of delayed-return foragers in aquatic environments. We refine models for the spread of food producers into eastern and southern Africa, demonstrating more complex trajectories of admixture than previously suggested. In Botswana, we show that Bantu ancestry post-dates admixture between pastoralists and foragers, suggesting an earlier spread of pastoralism than farming to southern Africa. Our findings demonstrate how processes of migration and admixture have markedly reshaped the genetic map of sub-Saharan Africa in the past few millennia and highlight the utility of combined archaeological and archaeogenetic approaches.

Genetic polymorphism and population structure ofEchinococcus ortleppi

Parasitology ◽  
2016 ◽  
Vol 144 (4) ◽  
pp. 450-458 ◽  
Author(s):  
F. ADDY ◽  
M. WASSERMANN ◽  
F. BANDA ◽  
H. MBAYA ◽  
J. ASCHENBORN ◽  
...  
Keyword(s):  
Genetic Polymorphism ◽  
South America ◽  
Southern Africa ◽  
Dna Sequences ◽  
Intraspecific Variability ◽  
Sensu Stricto ◽  
Sub Saharan Africa ◽  
Geographical Regions ◽  
Sub Saharan ◽  
Eastern And Southern Africa

SUMMARYThe zoonotic cestodeEchinococcus ortleppi(Lopez-Neyra and Soler Planas, 1943) is mainly transmitted between dogs and cattle. It occurs worldwide but is only found sporadically in most regions, with the notable exception of parts of southern Africa and South America. Its epidemiology is little understood and the extent of intraspecific variability is unknown. We have analysed in the present study the genetic diversity among 178E. ortleppiisolates from sub-Saharan Africa, Europe and South America using the complete mitochondrialcox1(1608 bp) andnad1(894 bp) DNA sequences. Genetic polymorphism within the loci revealed 15cox1and sixnad1haplotypes, respectively, and 20 haplotypes of the concatenated genes. Presence of most haplotypes was correlated to geographical regions, and only one haplotype had a wider spread in both eastern and southern Africa. Intraspecific microvariance was low in comparison withEchinococcus granulosussensu stricto, despite the wide geographic range of examined isolates. In addition, the various sub-populations showed only subtle deviation from neutrality and were mostly genetically differentiated. This is the first insight into the population genetics of the enigmatic cattle adaptedEchinococcus ortleppi. It, therefore, provides baseline data for biogeographical comparison amongE. ortleppiendemic regions and for tracing its translocation paths.

Embedding Indigenous Knowledge in Library and Information Science Education in Anglophone Eastern and Southern Africa

2017 ◽  
pp. 92-115 ◽  
Author(s):  
Patrick Ngulube
Keyword(s):  
Indigenous Knowledge ◽  
Southern Africa ◽  
Information Science ◽  
Sub Saharan Africa ◽  
Library And Information Science ◽  
Potential Contribution ◽  
University Curriculum ◽  
Sub Saharan ◽  
Eastern And Southern Africa ◽  
The University

There is need to re-examine the inclusion or exclusion of indigenous knowledge (IK) in the university curriculum in sub Saharan Africa (SSA). Western scientific knowledge on which the university curriculum in SSA is mainly based has proved to be inadequate in addressing developmental challenges. Using the curriculum of library and information science (LIS) departments in Anglophone east and southern Africa (AESA) as a case study, this chapter focuses on factors that influence the inclusion of IK in higher education in SSA. IK is recognised for its potential contribution to development by organisations such as the World Bank and African Union. Its inclusive ethos and accommodation of multiple realities also accounts for its popularity. In spite of that, IK has not established a stronghold in LIS curriculum in AESA. This study investigates the factors that influence its integration into the curriculum and makes recommendations based on the findings.

scholarly journals Ancient DNA reveals a multistep spread of the first herders into sub-Saharan Africa

Science ◽  
2019 ◽  
Vol 365 (6448) ◽  
pp. eaaw6275 ◽  
Author(s):  
Mary E. Prendergast ◽  
Mark Lipson ◽  
Elizabeth A. Sawchuk ◽  
Iñigo Olalde ◽  
Christine A. Ogola ◽  
...  
Keyword(s):  
Iron Age ◽  
Food Production ◽  
Sub Saharan Africa ◽  
Eastern Africa ◽  
Multiphase Model ◽  
Later Stone Age ◽  
Genome Wide ◽  
Genome Wide Data ◽  
Sub Saharan ◽  
Pastoral Neolithic

How food production first entered eastern Africa ~5000 years ago and the extent to which people moved with livestock is unclear. We present genome-wide data from 41 individuals associated with Later Stone Age, Pastoral Neolithic (PN), and Iron Age contexts in what are now Kenya and Tanzania to examine the genetic impacts of the spreads of herding and farming. Our results support a multiphase model in which admixture between northeastern African–related peoples and eastern African foragers formed multiple pastoralist groups, including a genetically homogeneous PN cluster. Additional admixture with northeastern and western African–related groups occurred by the Iron Age. These findings support several movements of food producers while rejecting models of minimal admixture with foragers and of genetic differentiation between makers of distinct PN artifacts.

Embedding Indigenous Knowledge in Library and Information Science Education in Anglophone Eastern and Southern Africa

2020 ◽  
pp. 255-278
Author(s):  
Patrick Ngulube
Keyword(s):  
Indigenous Knowledge ◽  
Southern Africa ◽  
Information Science ◽  
Sub Saharan Africa ◽  
Library And Information Science ◽  
Potential Contribution ◽  
University Curriculum ◽  
Sub Saharan ◽  
Eastern And Southern Africa ◽  
The University

There is need to re-examine the inclusion or exclusion of indigenous knowledge (IK) in the university curriculum in sub Saharan Africa (SSA). Western scientific knowledge on which the university curriculum in SSA is mainly based has proved to be inadequate in addressing developmental challenges. Using the curriculum of library and information science (LIS) departments in Anglophone east and southern Africa (AESA) as a case study, this chapter focuses on factors that influence the inclusion of IK in higher education in SSA. IK is recognised for its potential contribution to development by organisations such as the World Bank and African Union. Its inclusive ethos and accommodation of multiple realities also accounts for its popularity. In spite of that, IK has not established a stronghold in LIS curriculum in AESA. This study investigates the factors that influence its integration into the curriculum and makes recommendations based on the findings.

New radiocarbon dates for Eastern and Southern Africa

1972 ◽  
Vol 13 (1) ◽  
pp. 1-24 ◽  
Author(s):  
J. E. G. Sutton
Keyword(s):  
Iron Age ◽  
Southern Africa ◽  
Congo Basin ◽  
Sub Saharan Africa ◽  
Archaeological Sites ◽  
Stone Age ◽  
Radiocarbon Dates ◽  
Sub Saharan ◽  
Eastern And Southern Africa

This article is a follow-up to that of Mr D. W. Phillipson published in this Journal in 1970, and to the six earlier lists compiled for the whole of sub-Saharan Africa by Dr B. M. Fagan. I have endeavoured to include here all radiocarbon dates for archaeological sites of the Iron Age and most of those of the end of the Stone Age in the eastern and southern part of Africa—that is from Ethiopia, the Upper Nile and the Congo Basin southward—which have been published or made available since the preparation of the former articles. Some of these dates are already included in recent numbers of the Journal Radiocarbon, or have been mentioned in publications elsewhere, as indicated in the footnotes. A large proportion of these new dates, however, have not yet been published, and are included here through the agreement of the various individual archaeologists and research bodies, all of whom I wish to thank for their cooperation. In particular, I am indebted to Mr David Phillipson for his willing assistance in providing a number of contacts and relaying information from southern Africa.

Prospects for Africa's economies to end-2016

2016 ◽  
Keyword(s):  
South Africa ◽  
Southern Africa ◽  
Commodity Price ◽  
Sub Saharan Africa ◽  
Gdp Growth ◽  
Content Type ◽  
Idiosyncratic Shocks ◽  
Sub Saharan ◽  
Eastern And Southern Africa

Subject Prospects for Africa's economies to end-2016. Significance The IMF's most recent forecast of 3% GDP growth for sub-Saharan Africa (SSA) in 2016 represents a significant cut from the 4.25% it expected in October 2015. This is a consequence of sharp slowdowns in the region's two largest economies, Nigeria and South Africa, droughts in previously buoyant economies (notably in eastern and southern Africa), a variety of idiosyncratic shocks and a prolonged commodity price downturn.

scholarly journals Integration associations for Sub-Saharan Africa: history and prospects for development

2020 ◽  
Vol 10 (28-29) ◽  
pp. 52-62
Author(s):  
Mariia Kravchenko ◽  
Keyword(s):  
Free Trade ◽  
Southern Africa ◽  
Regional Integration ◽  
Free Trade Area ◽  
Sub Saharan Africa ◽  
African Unity ◽  
Economic Community ◽  
Trade Area ◽  
Sub Saharan ◽  
Eastern And Southern Africa

The article deals with the main integration associations of such a promising but controversial region, as Sub-Saharan Africa. The author emphasizes the continuity of regional integration associations’ formation that goes back to the colonial times, to the first half of the 20th century. Periodization of ongoing integration processes in Sub-Saharan Africa is proposed in the research. Key milestones for the further regional integration were: - 1963, the foundation of the Organisation of African Unity (OAU); and the beginning of Independence for many postcolonial countries of Sub-Saharan Africa; - 1980, the Lagos Plan of Action adoption that led to the establishment in future of the following integration associations for Sub-Saharan Africa: ECOWAS, Economic Community of West African States; COMESA, Common Market for Eastern and Southern Africa; ECCAS, Economic Community of Central African States; - 1991, the signing of the Abuja Treaty, which called for the African Economic Community creation as the new stage for economic cooperation and integration of the continent, including Sub-Saharan Africa; - 1999-2002, the Organisation of African Unity (OAU) transition into the African Union (AU), launching of new partnerships and integration associations for Sub-Saharan Africa, increased integration. At the beginning of the 21st century, there are serious economic and political factors for disintegration in the region. Nevertheless, the following integration associations, as stated in the article, proved to be effective: SADC, Southern African Development Community; EAC, East African Community; COMESA, Common Market for Eastern and Southern Africa. The author argues that the existence since 2015 the Tripartite Free Trade Area (TFTA) between EAC, COMESA and SADC marks a significant step forward for strengthening of integration associations for Sub-Saharan Africa, as well as for the achievement of African Union’s purpose to provide the African Continental Free Trade Area.

scholarly journals Drought tolerant maize for farmer adaptation to drought in sub-Saharan Africa: Determinants of adoption in eastern and southern Africa

2015 ◽  
Vol 133 (2) ◽  
pp. 283-299 ◽  
Author(s):  
Monica Fisher ◽  
Tsedeke Abate ◽  
Rodney W. Lunduka ◽  
Woinishet Asnake ◽  
Yoseph Alemayehu ◽  
...  
Keyword(s):  
Southern Africa ◽  
Sub Saharan Africa ◽  
Drought Tolerant ◽  
Sub Saharan ◽  
Eastern And Southern Africa ◽  
Adaptation To Drought

scholarly journals Global burden of active smoking among people living with HIV on antiretroviral therapy: a systematic review and meta-analysis

2021 ◽  
Vol 10 (1) ◽  
Author(s):  
Boni Maxime Ale ◽  
Franck Amahowe ◽  
Motto Malea Nganda ◽  
Célestin Danwang ◽  
Nelly Njeri Wakaba ◽  
...  
Keyword(s):  
Antiretroviral Therapy ◽  
Southern Africa ◽  
Sub Saharan Africa ◽  
People Living With Hiv ◽  
Art Adherence ◽  
Active Smoking ◽  
Suboptimal Adherence ◽  
Sub Saharan ◽  
Eastern And Southern Africa ◽  
Living With Hiv

Abstract Background Although the high burden of both active smoking and human immunodeficiency virus (HIV) is clearly known, the relationship between them is still not well characterized. Therefore, we estimated the global prevalence of active smoking in people living with HIV (PLHIV) on antiretroviral therapy (ART) and investigated the association between exposure to active smoking and risk for suboptimal adherence to ART. Main text: We searched PubMed, Embase, and Web of Science to identify articles published until September 19, 2019. Eligible studies reported the prevalence of active smoking in PLHIV on ART or investigated the association between active smoking and ART adherence; or enough data to compute these estimates. We used a random-effects model to pool data and quantified heterogeneity (I2). The global prevalence of active smoking was 36.1% (95% CI: 33.7–37.2; 329 prevalence data; 462 104 participants) with substantial heterogeneity. The prevalence increased with level of country income; from 10.1% (95% CI: 6.8–14.1) in low-income to 45.2% (95% CI: 42.7–47.7) in high-income countries; P < 0.0001. With regards to the Joint United Nations Programme on HIV/AIDS (UNAIDS) regions, the prevalence was higher in West and Central Europe and North America 45.4% (42.7–48.1) and lowest in the two UNAIDS regions of sub-Saharan Africa: Eastern and Southern Africa 10.7% (95% CI: 7.8–14.0) and West and Central Africa 4.4% (2.9–6.3); P < 0.0001. Globally, we estimated that there were 4 110 669 PLHIV on ART who were active smokers, among which the highest number was from Eastern and Southern Africa (35.9%) followed by Asia and the Pacific (25.9%). Active smoking was significantly associated with suboptimal ART adherence: pooled odds ratio 1.57 (95% CI: 1.37–1.80; I2 = 56.8%; 19 studies; 48 450 participants); even after considering adjusted estimates: 1.67 (95% CI: 1.39–2.01; I2 = 53.0%; 14 studies). Conclusions This study suggests a high prevalence of active smoking in PLHIV on ART and an association between active smoking and ART suboptimal adherence. As such, healthcare providers and policy makers should focus on adopting and implementing tobacco harm reduction strategies in HIV care, especially in sub-Saharan Africa known as epicenter of HIV pandemic with highest number of active tobacco smoking among PLHIV on ART.

scholarly journals Inferring adaptive gene-flow in recent African history

2017 ◽  
Author(s):  
George Busby ◽  
Ryan Christ ◽  
Gavin Band ◽  
Ellen Leffler ◽  
Quang Si Le ◽  
...  
Keyword(s):  
Gene Flow ◽  
African Ancestry ◽  
The Gambia ◽  
Sub Saharan Africa ◽  
Histocompatibility Complex ◽  
Genome Wide ◽  
Genome Wide Data ◽  
Multiple Regions ◽  
Novel Method ◽  
Sub Saharan

AbstractGene-flow from an ancestrally differentiated group has been shown to be a powerful source of selectively advantageous variants. To understand whether recent gene-flow may have contributed to adaptation among humans in sub-Saharan Africa, we applied a novel method to identify deviations in ancestry inferred from genome-wide data in 48 populations. Among the signals of ancestry deviation that we find in the Fula, an historically pastoralist ethnic group from the Gambia, are the region that encodes the lactose persistence phenotype, LCT/MCM6, which has the highest proportion of Eurasian ancestry in the genome. The region with the lowest proportion of non-African ancestry is across DARC, which encodes the Duffy null phenotype and is protective for Plasmodium vivax malaria. In the Jola from the Gambia and a Khoesan speaking group from Namibia we find multiple regions with inferred ancestry deviation including the Major Histocompatibility Complex. Our analysis shows the potential for adaptive gene-flow in recent human history.

Sign in / Sign up

Export Citation Format

Share Document