Chemical Synthesis of MT1 and MT7 Muscarinic Toxins: Critical Role of Arg-34 in Their Interaction with M1 Muscarinic Receptor

Gilles Mourier; Sébastien Dutertre; Carole Fruchart-Gaillard; André Ménez; Denis Servent

doi:10.1124/mol.63.1.26

Chemical Synthesis of MT1 and MT7 Muscarinic Toxins: Critical Role of Arg-34 in Their Interaction with M1 Muscarinic Receptor

Molecular Pharmacology ◽

10.1124/mol.63.1.26 ◽

2003 ◽

Vol 63 (1) ◽

pp. 26-35 ◽

Cited By ~ 38

Author(s):

Gilles Mourier ◽

Sébastien Dutertre ◽

Carole Fruchart-Gaillard ◽

André Ménez ◽

Denis Servent

Keyword(s):

Chemical Synthesis ◽

Muscarinic Receptor ◽

Critical Role ◽

Muscarinic Toxins ◽

M1 Muscarinic

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Critical Role of M3 Muscarinic Receptor in Insulin Secretion

Journal of Clinical Psychopharmacology ◽

10.1097/01.jcp.0000239789.83707.7d ◽

2006 ◽

Vol 26 (5) ◽

pp. 449-450 ◽

Cited By ~ 7

Author(s):

Ripu D. Jindal ◽

Matcheri S. Keshavan

Keyword(s):

Insulin Secretion ◽

Muscarinic Receptor ◽

Critical Role ◽

M3 Muscarinic Receptor

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The role of ryanodine receptors in the cyclic ADP ribose modulation of the M-like current in rodent m1 muscarinic receptor-transformed NG108-15 cells

The Journal of Physiology ◽

10.1111/j.1469-7793.1999.0023o.x ◽

1999 ◽

Vol 519 (1) ◽

pp. 23-34 ◽

Cited By ~ 13

Author(s):

Sarah E. H. Bowden ◽

Alexander A. Selyanko ◽

Jon Robbins

Keyword(s):

Muscarinic Receptor ◽

Ryanodine Receptors ◽

Cyclic Adp Ribose ◽

M1 Muscarinic

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The Role of the Aspartate-Arginine-Tyrosine Triad in the m1 Muscarinic Receptor: Mutations of Aspartate 122 and Tyrosine 124 Decrease Receptor Expression but Do Not Abolish Signaling

Molecular Pharmacology ◽

10.1124/mol.51.2.234 ◽

1997 ◽

Vol 51 (2) ◽

pp. 234-241 ◽

Cited By ~ 51

Author(s):

Zhi-Liang Lu ◽

Carol A. Curtis ◽

Philip G. Jones ◽

Jose Pavia ◽

Edward C. Hulme

Keyword(s):

Muscarinic Receptor ◽

Receptor Expression ◽

M1 Muscarinic

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Role of G proteins in mouse egg activation: Stimulatory effects of acetylcholine on the ZP2 to ZP2f conversion and pronuclear formation in eggs expressing a functional m1 muscarinic receptor

Developmental Biology ◽

10.1016/0012-1606(92)90233-7 ◽

1992 ◽

Vol 151 (1) ◽

pp. 288-296 ◽

Cited By ~ 46

Author(s):

Carmen J. Williams ◽

Richard M. Schultz ◽

Gregory S. Kopf

Keyword(s):

Muscarinic Receptor ◽

G Proteins ◽

Egg Activation ◽

M1 Muscarinic ◽

Pronuclear Formation ◽

Mouse Egg

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The role of M1 muscarinic receptor agonism of N-desmethylclozapine in the unique clinical effects of clozapine

Psychopharmacology ◽

10.1007/s00213-004-1940-5 ◽

2004 ◽

Vol 177 (1-2) ◽

pp. 207-216 ◽

Cited By ~ 153

Author(s):

D. M. Weiner ◽

H. Y. Meltzer ◽

I. Veinbergs ◽

E. M. Donohue ◽

T. A. Spalding ◽

...

Keyword(s):

Muscarinic Receptor ◽

Clinical Effects ◽

M1 Muscarinic

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The Role of the SLP in Autism Spectrum Disorder Screening and Assessment

Perspectives on Language Learning and Education ◽

10.1044/lle15.2.50 ◽

2008 ◽

Vol 15 (2) ◽

pp. 50-59 ◽

Cited By ~ 1

Author(s):

Amy Philofsky

Keyword(s):

Language Development ◽

Critical Role ◽

Children With Autism ◽

Autism Spectrum ◽

Children With Asd ◽

Prevalence Estimates ◽

Notable Increase ◽

Screening Assessment ◽

Critical Components

AbstractRecent prevalence estimates for autism have been alarming as a function of the notable increase. Speech-language pathologists play a critical role in screening, assessment and intervention for children with autism. This article reviews signs that may be indicative of autism at different stages of language development, and discusses the importance of several psychometric properties—sensitivity and specificity—in utilizing screening measures for children with autism. Critical components of assessment for children with autism are reviewed. This article concludes with examples of intervention targets for children with ASD at various levels of language development.

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