2-Methoxyestradiol, an Endogenous Estrogen Metabolite, Induces Apoptosis in Endothelial Cells and Inhibits Angiogenesis: Possible Role for Stress-Activated Protein Kinase Signaling Pathway and Fas Expression

Tian-Li Yue; Xinkang Wang; Calvert S. Louden; Shalley Gupta; Kodandaram Pillarisetti; Juan-Li Gu; Timothy K. Hart; Paul G. Lysko; Giora Z. Feuerstein

doi:10.1124/mol.51.6.951

2-Methoxyestradiol, an Endogenous Estrogen Metabolite, Induces Apoptosis in Endothelial Cells and Inhibits Angiogenesis: Possible Role for Stress-Activated Protein Kinase Signaling Pathway and Fas Expression

Molecular Pharmacology ◽

10.1124/mol.51.6.951 ◽

1997 ◽

Vol 51 (6) ◽

pp. 951-962 ◽

Cited By ~ 121

Author(s):

Tian-Li Yue ◽

Xinkang Wang ◽

Calvert S. Louden ◽

Shalley Gupta ◽

Kodandaram Pillarisetti ◽

...

Keyword(s):

Endothelial Cells ◽

Protein Kinase ◽

Signaling Pathway ◽

Kinase Signaling ◽

Estrogen Metabolite ◽

Endogenous Estrogen ◽

Protein Kinase Signaling ◽

Kinase Signaling Pathway

Download Full-text

Neuroprotective Effects of Raloxifene on Aβ25-35-induced Damages in PC12 Cells via Mitogen-activated Protein Kinase Signaling Pathway

Journal of Reproduction and Contraception ◽

10.1016/s1001-7844(13)60001-2 ◽

2012 ◽

Vol 23 (1) ◽

pp. 1-16 ◽

Cited By ~ 2

Author(s):

Xue DAI ◽

Jie WU ◽

Xue-ping SUN ◽

Li GAO ◽

Yu-gui CUI ◽

...

Keyword(s):

Protein Kinase ◽

Signaling Pathway ◽

Pc12 Cells ◽

Mitogen Activated Protein Kinase ◽

Kinase Signaling ◽

Neuroprotective Effects ◽

Mitogen Activated Protein ◽

Protein Kinase Signaling ◽

Kinase Signaling Pathway

Download Full-text

Natural Mineralized Scaffolds Promote the Dentinogenic Potential of Dental Pulp Stem Cells Via the Mitogen-Activated Protein Kinase Signaling Pathway

Tissue Engineering Part A ◽

10.1089/ten.tea.2011.0269 ◽

2012 ◽

Vol 18 (7-8) ◽

pp. 677-691 ◽

Cited By ~ 31

Author(s):

Hongmei Zhang ◽

Shiyu Liu ◽

Yalei Zhou ◽

Jiali Tan ◽

Honglei Che ◽

...

Keyword(s):

Stem Cells ◽

Protein Kinase ◽

Signaling Pathway ◽

Dental Pulp ◽

Dental Pulp Stem Cells ◽

Mitogen Activated Protein Kinase ◽

Kinase Signaling ◽

Mitogen Activated Protein ◽

Protein Kinase Signaling ◽

Kinase Signaling Pathway

Download Full-text

The Ras/cAMP-dependent Protein Kinase Signaling Pathway Regulates an Early Step of the Autophagy Process inSaccharomyces cerevisiae

Journal of Biological Chemistry ◽

10.1074/jbc.m400272200 ◽

2004 ◽

Vol 279 (20) ◽

pp. 20663-20671 ◽

Cited By ~ 140

Author(s):

Yelena V. Budovskaya ◽

Joseph S. Stephan ◽

Fulvio Reggiori ◽

Daniel J. Klionsky ◽

Paul K. Herman

Keyword(s):

Protein Kinase ◽

Signaling Pathway ◽

Kinase Signaling ◽

Early Step ◽

Dependent Protein Kinase ◽

Camp Dependent Protein Kinase ◽

Dependent Protein ◽

Protein Kinase Signaling ◽

Kinase Signaling Pathway

Download Full-text

Ginsenoside Rg3 suppresses mast cell–mediated allergic inflammation via mitogen-activated protein kinase signaling pathway

Journal of Ginseng Research ◽

10.1016/j.jgr.2018.02.008 ◽

2019 ◽

Vol 43 (2) ◽

pp. 282-290 ◽

Cited By ~ 12

Author(s):

Ji-Ye Kee ◽

Seung-Heon Hong

Keyword(s):

Mast Cell ◽

Protein Kinase ◽

Signaling Pathway ◽

Allergic Inflammation ◽

Mitogen Activated Protein Kinase ◽

Kinase Signaling ◽

Ginsenoside Rg3 ◽

Mitogen Activated Protein ◽

Protein Kinase Signaling ◽

Kinase Signaling Pathway

Download Full-text

Circular RNA regulates the onset and progression of cancer through the mitogen‑activated protein kinase signaling pathway (Review)

Oncology Letters ◽

10.3892/ol.2021.13078 ◽

2021 ◽

Vol 22 (6) ◽

Author(s):

Qun Lai ◽

Min Wang ◽

Chunmei Hu ◽

Yan Tang ◽

Yarong Li ◽

...

Keyword(s):

Protein Kinase ◽

Signaling Pathway ◽

Circular Rna ◽

Mitogen Activated Protein Kinase ◽

Kinase Signaling ◽

Mitogen Activated Protein ◽

Protein Kinase Signaling ◽

Kinase Signaling Pathway

Download Full-text

Pancreatic Stellate Cell Activation by Ethanol and Acetaldehyde: Is it Mediated by the Mitogen-Activated Protein Kinase Signaling Pathway?

Pancreas ◽

10.1097/00006676-200308000-00008 ◽

2003 ◽

Vol 27 (2) ◽

pp. 150-160 ◽

Cited By ~ 62

Author(s):

J. A. McCarroll ◽

P. A. Phillips ◽

S. Park ◽

E. Doherty ◽

R. C. Pirola ◽

...

Keyword(s):

Protein Kinase ◽

Signaling Pathway ◽

Cell Activation ◽

Stellate Cell ◽

Mitogen Activated Protein Kinase ◽

Kinase Signaling ◽

Pancreatic Stellate Cell ◽

Mitogen Activated Protein ◽

Protein Kinase Signaling ◽

Kinase Signaling Pathway

Download Full-text

Constitutive Activation of the Mitogen-Activated Protein Kinase Signaling Pathway in Acral Melanomas

Journal of Investigative Dermatology ◽

10.1111/j.0022-202x.2005.23812.x ◽

2005 ◽

Vol 125 (2) ◽

pp. 318-322 ◽

Cited By ~ 44

Author(s):

Minoru Takata ◽

Yasufumi Goto ◽

Nami Ichii ◽

Maki Yamaura ◽

Hiroshi Murata ◽

...

Keyword(s):

Protein Kinase ◽

Signaling Pathway ◽

Mitogen Activated Protein Kinase ◽

Kinase Signaling ◽

Constitutive Activation ◽

Mitogen Activated Protein ◽

Protein Kinase Signaling ◽

Kinase Signaling Pathway

Download Full-text

Early intervention with Didang decoction delays macrovascular lesions in diabetic rats through regulating AMP-activated protein kinase signaling pathway

Chinese Journal of Natural Medicines ◽

10.1016/s1875-5364(18)30018-9 ◽

2017 ◽

Vol 15 (11) ◽

pp. 847-854 ◽

Cited By ~ 1

Author(s):

Dan-Dan REN ◽

Jing LI ◽

Bai CHANG ◽

Chun-Shen LI ◽

Ju-Hong YANG

Keyword(s):

Early Intervention ◽

Protein Kinase ◽

Signaling Pathway ◽

Diabetic Rats ◽

Kinase Signaling ◽

Amp Activated Protein Kinase ◽

Protein Kinase Signaling ◽

Kinase Signaling Pathway

Download Full-text

Four new tirucallane-type triterpenoids from Sapindus mukorossi Gaertn. flowers induced neurite outgrowth in PC12 cells related to insulin-like growth factor 1 receptor/phosphoinositide 3-kinase/extracellular regulated protein kinase signaling pathway

Phytochemistry Letters ◽

10.1016/j.phytol.2019.08.011 ◽

2019 ◽

Vol 34 ◽

pp. 5-12

Author(s):

Yanhui Wang ◽

Xueli Cao ◽

Boyu Qin ◽

Ying Wang ◽

Lan Xiang ◽

...

Keyword(s):

Growth Factor ◽

Protein Kinase ◽

Neurite Outgrowth ◽

Signaling Pathway ◽

Pc12 Cells ◽

Insulin Like Growth Factor ◽

Kinase Signaling ◽

Phosphoinositide 3 Kinase ◽

Protein Kinase Signaling ◽

Kinase Signaling Pathway

Download Full-text

Epigallocatechin‐3‐gallate activates the AMP‐activated protein kinase signaling pathway to reduce lipid accumulation in canine hepatocytes

Journal of Cellular Physiology ◽

10.1002/jcp.29869 ◽

2020 ◽

Vol 236 (1) ◽

pp. 405-416

Author(s):

Hongyan Ding ◽

Yu Li ◽

Wei Li ◽

Huanqing Tao ◽

Leihong Liu ◽

...

Keyword(s):

Protein Kinase ◽

Signaling Pathway ◽

Lipid Accumulation ◽

Kinase Signaling ◽

Amp Activated Protein Kinase ◽

Protein Kinase Signaling ◽

Kinase Signaling Pathway

Download Full-text