scholarly journals Identification of Stage-Specific Gene Modulation during Early Thymocyte Development by Whole-Genome Profiling Analysis after Aryl Hydrocarbon Receptor Activation

2010 ◽  
Vol 77 (5) ◽  
pp. 773-783 ◽  
Author(s):  
Michael D. Laiosa ◽  
Jeffrey H. Mills ◽  
Zhi-Wei Lai ◽  
Kameshwar P. Singh ◽  
Frank A. Middleton ◽  
...  
Keyword(s):  
Aryl Hydrocarbon Receptor ◽  
Receptor Activation ◽  
Specific Gene ◽  
Whole Genome ◽  
Gene Modulation ◽  
Thymocyte Development ◽  
Aryl Hydrocarbon ◽  
Genome Profiling ◽  
Profiling Analysis ◽  
Whole Genome Profiling

scholarly journals Whole-Genome Profiling in Liposarcomas Reveals Genetic Alterations Common to Specific Telomere Maintenance Mechanisms

2007 ◽  
Vol 67 (19) ◽  
pp. 9221-9228 ◽  
Author(s):  
Jay E. Johnson ◽  
Edward J. Gettings ◽  
Jaclyn Schwalm ◽  
Jianming Pei ◽  
Joseph R. Testa ◽  
...  
Keyword(s):  
Genetic Alterations ◽  
Telomere Maintenance ◽  
Whole Genome ◽  
Genome Profiling ◽  
Whole Genome Profiling

scholarly journals Aryl Hydrocarbon Receptor Activation Impairs Extracellular Matrix Remodeling during Zebra Fish fin Regeneration

2006 ◽  
Vol 95 (1) ◽  
pp. 215-226 ◽  
Author(s):  
Eric A. Andreasen ◽  
Lijoy K. Mathew ◽  
Christiane V. Löhr ◽  
Rachelle Hasson ◽  
Robert L. Tanguay
Keyword(s):  
Extracellular Matrix ◽  
Aryl Hydrocarbon Receptor ◽  
Receptor Activation ◽  
Extracellular Matrix Remodeling ◽  
Matrix Remodeling ◽  
Zebra Fish ◽  
Fin Regeneration ◽  
Aryl Hydrocarbon

scholarly journals Detection of Aryl Hydrocarbon Receptor Activation by Some Chemicals in Food Using a Reporter Gene Assay

Foods ◽  
2016 ◽  
Vol 5 (1) ◽  
pp. 15 ◽  
Author(s):  
Yoshiaki Amakura ◽  
Tomoaki Tsutsumi ◽  
Morio Yoshimura ◽  
Masafumi Nakamura ◽  
Hiroshi Handa ◽  
...  
Keyword(s):  
Aryl Hydrocarbon Receptor ◽  
Reporter Gene ◽  
Receptor Activation ◽  
Reporter Gene Assay ◽  
Aryl Hydrocarbon ◽  
Gene Assay

scholarly journals Spiked GBS: a unified, open platform for single marker genotyping and whole-genome profiling

BMC Genomics ◽  
2015 ◽  
Vol 16 (1) ◽  
Author(s):  
Trevor W Rife ◽  
Shuangye Wu ◽  
Robert L Bowden ◽  
Jesse A Poland
Keyword(s):  
Whole Genome ◽  
Open Platform ◽  
Genome Profiling ◽  
Single Marker ◽  
Whole Genome Profiling

Aryl Hydrocarbon Receptor and Its Diverse Ligands and Functions: An Exposome Receptor

2021 ◽  
Vol 62 (1) ◽  
Author(s):  
Lucie Larigot ◽  
Louise Benoit ◽  
Meriem Koual ◽  
Céline Tomkiewicz ◽  
Robert Barouki ◽  
...  
Keyword(s):  
Aryl Hydrocarbon Receptor ◽  
Bacterial Infections ◽  
Critical Role ◽  
Time Frame ◽  
Receptor Activation ◽  
Annual Review ◽  
Publication Date ◽  
Pharmacological Characterization ◽  
Cancer Pathways ◽  
Aryl Hydrocarbon

The aryl hydrocarbon receptor (AhR) is a transcriptional factor that regulates multiple functions following its activation by a variety of ligands, including xenobiotics, natural products, microbiome metabolites, and endogenous molecules. Because of this diversity, the AhR constitutes an exposome receptor. One of its main functions is to regulate several lines of defense against chemical insults and bacterial infections. Indeed, in addition to its well-established detoxication function, it has several functions at physiological barriers, and it plays a critical role in immunomodulation. The AhR is also involved in the development of several organs and their homeostatic maintenance. Its activity depends on the type of ligand and on the time frame of the receptor activation, which can be either sustained or transient, leading in some cases to opposite modes of regulations as illustrated in the regulation of different cancer pathways. The development of selective modulators and their pharmacological characterization are important areas of research. Expected final online publication date for the Annual Review of Pharmacology and Toxicology, Volume 62 is January 2022. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.

Sign in / Sign up

Export Citation Format

Share Document