Delineating the Contribution of Secretory Transporters in the Efflux of Etoposide Using Madin-Darby Canine Kidney (MDCK) Cells Overexpressing P-Glycoprotein (Pgp), Multidrug Resistance-Associated Protein (MRP1), and Canalicular Multispecific Organic Anion Transporter (cMOAT)

Ailan Guo; William Marinaro; Peidi Hu; Patrick J. Sinko

doi:10.1124/dmd.30.4.457

Delineating the Contribution of Secretory Transporters in the Efflux of Etoposide Using Madin-Darby Canine Kidney (MDCK) Cells Overexpressing P-Glycoprotein (Pgp), Multidrug Resistance-Associated Protein (MRP1), and Canalicular Multispecific Organic Anion Transporter (cMOAT)

Drug Metabolism and Disposition ◽

10.1124/dmd.30.4.457 ◽

2002 ◽

Vol 30 (4) ◽

pp. 457-463 ◽

Cited By ~ 65

Author(s):

Ailan Guo ◽

William Marinaro ◽

Peidi Hu ◽

Patrick J. Sinko

Keyword(s):

Multidrug Resistance ◽

Mdck Cells ◽

Organic Anion ◽

Organic Anion Transporter ◽

Madin Darby Canine Kidney ◽

P Glycoprotein ◽

Anion Transporter ◽

Darby Canine Kidney ◽

Canine Kidney

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Human Renal Organic Anion Transporter 1-Dependent Uptake and Toxicity of Mercuric-Thiol Conjugates in Madin-Darby Canine Kidney Cells

Molecular Pharmacology ◽

10.1124/mol.63.3.590 ◽

2003 ◽

Vol 63 (3) ◽

pp. 590-596 ◽

Cited By ~ 68

Author(s):

Amy G. Aslamkhan ◽

Yong-Hae Han ◽

Xiao-Ping Yang ◽

Rudolfs K. Zalups ◽

John B. Pritchard

Keyword(s):

Organic Anion ◽

Organic Anion Transporter ◽

Kidney Cells ◽

Madin Darby Canine Kidney ◽

Anion Transporter ◽

Darby Canine Kidney ◽

Canine Kidney

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Transport of N-Acetylcysteine S-Conjugates of Methylmercury in Madin-Darby Canine Kidney Cells Stably Transfected with Human Isoform of Organic Anion Transporter 1

Journal of Pharmacology and Experimental Therapeutics ◽

10.1124/jpet.105.086645 ◽

2005 ◽

Vol 314 (3) ◽

pp. 1158-1168 ◽

Cited By ~ 32

Author(s):

Rudolfs K. Zalups ◽

Sarfaraz Ahmad

Keyword(s):

Organic Anion ◽

Organic Anion Transporter ◽

Kidney Cells ◽

Madin Darby Canine Kidney ◽

Anion Transporter ◽

Darby Canine Kidney ◽

Canine Kidney

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Identification of the Hepatic Efflux Transporters of Organic Anions Using Double-Transfected Madin-Darby Canine Kidney II Cells Expressing Human Organic Anion-Transporting Polypeptide 1B1 (OATP1B1)/Multidrug Resistance-Associated Protein 2, OATP1B1/Multidrug Resistance 1, and OATP1B1/Breast Cancer Resistance Protein

Journal of Pharmacology and Experimental Therapeutics ◽

10.1124/jpet.105.085589 ◽

2005 ◽

Vol 314 (3) ◽

pp. 1059-1067 ◽

Cited By ~ 141

Author(s):

Soichiro Matsushima ◽

Kazuya Maeda ◽

Chihiro Kondo ◽

Masaru Hirano ◽

Makoto Sasaki ◽

...

Keyword(s):

Multidrug Resistance ◽

Breast Cancer Resistance Protein ◽

Organic Anion ◽

Efflux Transporters ◽

Cancer Resistance ◽

Madin Darby Canine Kidney ◽

Organic Anion Transporting Polypeptide ◽

Resistance Protein ◽

Darby Canine Kidney ◽

Canine Kidney

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0067 P-glycoprotein expression in Madin-Darby canine kidney (MDCK) cells treated with levetiracetam

Journal of the Neurological Sciences ◽

10.1016/s0022-510x(05)80442-3 ◽

2005 ◽

Vol 238 ◽

pp. S117-S118

Keyword(s):

Mdck Cells ◽

Madin Darby Canine Kidney ◽

P Glycoprotein ◽

Darby Canine Kidney ◽

Canine Kidney

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Cloning and heterologous expression of the ovine (Ovis aries) P-glycoprotein (Mdr1) in Madin-Darby canine kidney (MDCK) cells

Journal of Veterinary Pharmacology and Therapeutics ◽

10.1111/j.1365-2885.2009.01141.x ◽

2010 ◽

Vol 33 (3) ◽

pp. 304-311 ◽

Cited By ~ 6

Author(s):

D. ZAHNER ◽

J. ALBER ◽

E. PETZINGER

Keyword(s):

Heterologous Expression ◽

Mdck Cells ◽

Ovis Aries ◽

Madin Darby Canine Kidney ◽

P Glycoprotein ◽

Darby Canine Kidney ◽

Canine Kidney

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JBP485 attenuates vancomycin-induced nephrotoxicity by regulating the expressions of organic anion transporter (Oat) 1, Oat3, organic cation transporter 2 (Oct2), multidrug resistance-associated protein 2 (Mrp2) and P-glycoprotein (P-gp) in rats

Toxicology Letters ◽

10.1016/j.toxlet.2018.06.1220 ◽

2018 ◽

Vol 295 ◽

pp. 195-204 ◽

Cited By ~ 11

Author(s):

Shijie Wen ◽

Changyuan Wang ◽

Xiaokui Huo ◽

Qiang Meng ◽

Zhihao Liu ◽

...

Keyword(s):

Multidrug Resistance ◽

Organic Cation ◽

Organic Anion ◽

Organic Cation Transporter ◽

Organic Anion Transporter ◽

Glycoprotein P ◽

P Glycoprotein ◽

Anion Transporter ◽

Organic Cation Transporter 2

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If the KI Is Defined by the Free Energy of Binding to P-Glycoprotein, Which Kinetic Parameters Define the IC50 for the Madin-Darby Canine Kidney II Cell Line Overexpressing Human Multidrug Resistance 1 Confluent Cell Monolayer?

Drug Metabolism and Disposition ◽

10.1124/dmd.109.029843 ◽

2009 ◽

Vol 38 (2) ◽

pp. 260-269 ◽

Cited By ~ 22

Author(s):

Annie Albin Lumen ◽

Poulomi Acharya ◽

Joseph W. Polli ◽

Andrew Ayrton ◽

Harma Ellens ◽

...

Keyword(s):

Free Energy ◽

Multidrug Resistance ◽

Kinetic Parameters ◽

Cell Monolayer ◽

Madin Darby Canine Kidney ◽

P Glycoprotein ◽

Confluent Cell ◽

Free Energy Of Binding ◽

Darby Canine Kidney ◽

Canine Kidney

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Transport of the Dipeptidyl Peptidase-4 Inhibitor Sitagliptin by Human Organic Anion Transporter 3, Organic Anion Transporting Polypeptide 4C1, and Multidrug Resistance P-glycoprotein

Journal of Pharmacology and Experimental Therapeutics ◽

10.1124/jpet.106.116517 ◽

2007 ◽

Vol 321 (2) ◽

pp. 673-683 ◽

Cited By ~ 121

Author(s):

Xiao-Yan Chu ◽

Kelly Bleasby ◽

Jocelyn Yabut ◽

Xiaoxin Cai ◽

Grace Hoyee Chan ◽

...

Keyword(s):

Multidrug Resistance ◽

Organic Anion ◽

Dipeptidyl Peptidase ◽

Organic Anion Transporter ◽

Dipeptidyl Peptidase 4 ◽

Organic Anion Transporting Polypeptide ◽

P Glycoprotein ◽

Anion Transporter ◽

Dipeptidyl Peptidase 4 Inhibitor ◽

Organic Anion Transporter 3

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Transcellular Transport of Organic Anions Across a Double-transfected Madin-Darby Canine Kidney II Cell Monolayer Expressing Both Human Organic Anion-transporting Polypeptide (OATP2/SLC21A6) and Multidrug Resistance-associated Protein 2 (MRP2/ABCC2)

Journal of Biological Chemistry ◽

10.1074/jbc.m109081200 ◽

2001 ◽

Vol 277 (8) ◽

pp. 6497-6503 ◽

Cited By ~ 183

Author(s):

Makoto Sasaki ◽

Hiroshi Suzuki ◽

Kousei Ito ◽

Takaaki Abe ◽

Yuichi Sugiyama

Keyword(s):

Multidrug Resistance ◽

Organic Anion ◽

Cell Monolayer ◽

Organic Anions ◽

Madin Darby Canine Kidney ◽

Transcellular Transport ◽

Organic Anion Transporting Polypeptide ◽

Darby Canine Kidney ◽

Canine Kidney

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Differential sensitivity of Madin-Darby canine kidney (MDCK) cells to epinephrine

The journal of nutrition health & aging ◽

10.1007/s12603-015-0604-y ◽

2015 ◽

Vol 20 (5) ◽

pp. 486-493 ◽

Cited By ~ 4

Author(s):

P. Muthuraman ◽

P. C. Nagajyothi ◽

M. Chandrasekaran ◽

G. Enkhtaivan ◽

B. Venkitasamy ◽

...

Keyword(s):

Mdck Cells ◽

Differential Sensitivity ◽

Madin Darby Canine Kidney ◽

Darby Canine Kidney ◽

Canine Kidney

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