Threonine-290 Regulates Nuclear Translocation of the Human Pregnane X Receptor through Its Phosphorylation/Dephosphorylation by Ca2+/Calmodulin-Dependent Protein Kinase II and Protein Phosphatase 1

Junko Sugatani; Yoshiki Hattori; Yuji Noguchi; Masahiko Yamaguchi; Yasuhiro Yamazaki; Akira Ikari

doi:10.1124/dmd.114.059139

Threonine-290 Regulates Nuclear Translocation of the Human Pregnane X Receptor through Its Phosphorylation/Dephosphorylation by Ca2+/Calmodulin-Dependent Protein Kinase II and Protein Phosphatase 1

Drug Metabolism and Disposition ◽

10.1124/dmd.114.059139 ◽

2014 ◽

Vol 42 (10) ◽

pp. 1708-1718 ◽

Cited By ~ 10

Author(s):

Junko Sugatani ◽

Yoshiki Hattori ◽

Yuji Noguchi ◽

Masahiko Yamaguchi ◽

Yasuhiro Yamazaki ◽

...

Keyword(s):

Protein Kinase ◽

Protein Phosphatase ◽

Nuclear Translocation ◽

Pregnane X Receptor ◽

Protein Phosphatase 1 ◽

Dependent Protein Kinase ◽

Protein Kinase Ii ◽

Dependent Protein

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Age-Dependent Targeting of Protein Phosphatase 1 to Ca2+/Calmodulin-Dependent Protein Kinase II by Spinophilin in Mouse Striatum

PLoS ONE ◽

10.1371/journal.pone.0031554 ◽

2012 ◽

Vol 7 (2) ◽

pp. e31554 ◽

Cited By ~ 14

Author(s):

Anthony J. Baucum ◽

Stefan Strack ◽

Roger J. Colbran

Keyword(s):

Protein Kinase ◽

Protein Phosphatase ◽

Protein Phosphatase 1 ◽

Dependent Protein Kinase ◽

Mouse Striatum ◽

Age Dependent ◽

Protein Kinase Ii ◽

Dependent Protein

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An ultrasensitive Ca2+/calmodulin-dependent protein kinase II-protein phosphatase 1 switch facilitates specificity in postsynaptic calcium signaling

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.1932759100 ◽

2003 ◽

Vol 100 (18) ◽

pp. 10512-10517 ◽

Cited By ~ 127

Author(s):

J. M. Bradshaw ◽

Y. Kubota ◽

T. Meyer ◽

H. Schulman

Keyword(s):

Protein Kinase ◽

Calcium Signaling ◽

Protein Phosphatase ◽

Protein Phosphatase 1 ◽

Dependent Protein Kinase ◽

Protein Kinase Ii ◽

Dependent Protein ◽

Postsynaptic Calcium

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The role of autophosphorylation of cAMP-dependent protein kinase II in the inhibition of protein phosphatase-1

International Journal of Biochemistry ◽

10.1016/0020-711x(89)90056-6 ◽

1989 ◽

Vol 21 (10) ◽

pp. 1137-1141 ◽

Cited By ~ 7

Author(s):

György Vereb ◽

Pal Gergely

Keyword(s):

Protein Kinase ◽

Protein Phosphatase ◽

Protein Phosphatase 1 ◽

Dependent Protein Kinase ◽

Camp Dependent Protein Kinase ◽

Protein Kinase Ii ◽

Dependent Protein

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Ca2+/calmodulin-dependent protein kinase II regulation by inhibitor 1 of protein phosphatase 1 alleviates necroptosis in high glucose-induced cardiomyocytes injury

Biochemical Pharmacology ◽

10.1016/j.bcp.2019.02.022 ◽

2019 ◽

Vol 163 ◽

pp. 194-205 ◽

Cited By ~ 7

Author(s):

Linlin Sun ◽

Yun Chen ◽

Huiqin Luo ◽

Mengting Xu ◽

Guoliang Meng ◽

...

Keyword(s):

Protein Kinase ◽

High Glucose ◽

Protein Phosphatase ◽

Protein Phosphatase 1 ◽

Dependent Protein Kinase ◽

Protein Kinase Ii ◽

Dependent Protein

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Protein phosphatase 1 is involved in the dissociation of Ca2+ /calmodulin-dependent protein kinase II from postsynaptic densities

FEBS Letters ◽

10.1016/s0014-5793(99)00226-4 ◽

1999 ◽

Vol 446 (2-3) ◽

pp. 239-242 ◽

Cited By ~ 35

Author(s):

Yoshiyuki Yoshimura ◽

Yoshimi Sogawa ◽

Takashi Yamauchi

Keyword(s):

Protein Kinase ◽

Protein Phosphatase ◽

Protein Phosphatase 1 ◽

Dependent Protein Kinase ◽

Protein Kinase Ii ◽

Dependent Protein

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Nuclear Translocation of Calcium/Calmodulin-dependent Protein Kinase IIδ3 Promoted by Protein Phosphatase-1 Enhances Brain-derived Neurotrophic Factor Expression in Dopaminergic Neurons

Journal of Biological Chemistry ◽

10.1074/jbc.m115.664920 ◽

2015 ◽

Vol 290 (35) ◽

pp. 21663-21675 ◽

Cited By ~ 11

Author(s):

Norifumi Shioda ◽

Masahiro Sawai ◽

Yuta Ishizuka ◽

Tomoaki Shirao ◽

Kohji Fukunaga

Keyword(s):

Protein Kinase ◽

Neurotrophic Factor ◽

Protein Phosphatase ◽

Dopaminergic Neurons ◽

Nuclear Translocation ◽

Protein Phosphatase 1 ◽

Dependent Protein Kinase ◽

Calcium Calmodulin Dependent ◽

Factor Expression ◽

Dependent Protein

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Involvement of protein phosphatase 2C in dephosphorylation of autophosphorylated Ca2+/calmodulin-dependent protein kinase II.

The Japanese Journal of Pharmacology ◽

10.1016/s0021-5198(19)50535-2 ◽

1994 ◽

Vol 64 ◽

pp. 225

Author(s):

Kohji Fukunaga ◽

Takayasu Kobayashi ◽

Shinri Tamura ◽

Eishichi Miyamoto

Keyword(s):

Protein Kinase ◽

Protein Phosphatase ◽

Dependent Protein Kinase ◽

Protein Phosphatase 2C ◽

Protein Kinase Ii ◽

Dependent Protein

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Protein phosphatase 1 and phosphatase 1 nuclear targeting subunit-dependent regulation of DNA-dependent protein kinase and non-homologous end joining

Nucleic Acids Research ◽

10.1093/nar/gkx686 ◽

2017 ◽

Vol 45 (18) ◽

pp. 10583-10594 ◽

Cited By ~ 12

Author(s):

Songli Zhu ◽

Laura A. Fisher ◽

Tadayoshi Bessho ◽

Aimin Peng

Keyword(s):

Protein Kinase ◽

Protein Phosphatase ◽

Protein Phosphatase 1 ◽

End Joining ◽

Nuclear Targeting ◽

Dependent Protein Kinase ◽

Dependent Protein ◽

Non Homologous End Joining

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A Novel Protein Phosphatase That Dephosphorylates and Regulates Ca2+/Calmodulin-dependent Protein Kinase II

Journal of Biological Chemistry ◽

10.1074/jbc.273.4.1904 ◽

1998 ◽

Vol 273 (4) ◽

pp. 1904-1910 ◽

Cited By ~ 68

Author(s):

Atsuhiko Ishida ◽

Isamu Kameshita ◽

Hitoshi Fujisawa

Keyword(s):

Protein Kinase ◽

Protein Phosphatase ◽

Dependent Protein Kinase ◽

Protein Kinase Ii ◽

Dependent Protein ◽

Novel Protein

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Herbal formula GAPT prevents beta amyloid deposition induced Ca2+/Calmodulin-dependent protein kinase II and Ca2+/Calmodulin-dependent protein phosphatase 2B imbalance in APPV717I mice

BMC Complementary and Alternative Medicine ◽

10.1186/s12906-016-1144-7 ◽

2016 ◽

Vol 16 (1) ◽

Cited By ~ 3

Author(s):

Jing Shi ◽

Xuekai Zhang ◽

Long Yin ◽

Mingqing Wei ◽

Jingnian Ni ◽

...

Keyword(s):

Protein Kinase ◽

Protein Phosphatase ◽

Beta Amyloid ◽

Amyloid Deposition ◽

Herbal Formula ◽

Dependent Protein Kinase ◽

Protein Phosphatase 2B ◽

Protein Kinase Ii ◽

Dependent Protein

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