Modeling Human Nonalcoholic Steatohepatitis-Associated Changes in Drug Transporter Expression Using Experimental Rodent Models

Mark J. Canet; Rhiannon N. Hardwick; April D. Lake; Anika L. Dzierlenga; John D. Clarke; Nathan J. Cherrington

doi:10.1124/dmd.113.055996

Modeling Human Nonalcoholic Steatohepatitis-Associated Changes in Drug Transporter Expression Using Experimental Rodent Models

Drug Metabolism and Disposition ◽

10.1124/dmd.113.055996 ◽

2014 ◽

Vol 42 (4) ◽

pp. 586-595 ◽

Cited By ~ 34

Author(s):

Mark J. Canet ◽

Rhiannon N. Hardwick ◽

April D. Lake ◽

Anika L. Dzierlenga ◽

John D. Clarke ◽

...

Keyword(s):

Nonalcoholic Steatohepatitis ◽

Rodent Models ◽

Drug Transporter ◽

Transporter Expression

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Renal Transporter Expression Changes in Rodent Models of Nonalcoholic Steatohepatitis

The FASEB Journal ◽

10.1096/fasebj.2021.35.s1.02486 ◽

2021 ◽

Vol 35 (S1) ◽

Author(s):

Kayla Frost ◽

Joseph Jilek ◽

Erica Toth ◽

Michael Goedken ◽

Nathan Cherrington

Keyword(s):

Nonalcoholic Steatohepatitis ◽

Rodent Models ◽

Renal Transporter ◽

Transporter Expression

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Drug Transporter Expression and Localization in Rat Nasal Respiratory and Olfactory Mucosa and Olfactory Bulb: Fig. 1.

Drug Metabolism and Disposition ◽

10.1124/dmd.110.034611 ◽

2010 ◽

Vol 38 (10) ◽

pp. 1644-1647 ◽

Cited By ~ 19

Author(s):

Mary Beth Genter ◽

Mansi Krishan ◽

Lisa M. Augustine ◽

Nathan J. Cherrington

Keyword(s):

Olfactory Bulb ◽

Olfactory Mucosa ◽

Drug Transporter ◽

Transporter Expression

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Independent Regulation of Apical and Basolateral Drug Transporter Expression and Function in Placental Trophoblasts by Cytokines, Steroids, and Growth Factors

Drug Metabolism and Disposition ◽

10.1124/dmd.106.011478 ◽

2007 ◽

Vol 35 (4) ◽

pp. 595-601 ◽

Cited By ~ 116

Author(s):

Denis A. Evseenko ◽

James W. Paxton ◽

Jeffrey A. Keelan

Keyword(s):

Growth Factors ◽

Drug Transporter ◽

And Function ◽

Transporter Expression

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Antiretroviral Drug Concentrations in Lymph Nodes: A Cross-Species Comparison of the Effect of Drug Transporter Expression, Viral Infection, and Sex in Humanized Mice, Nonhuman Primates, and Humans

Journal of Pharmacology and Experimental Therapeutics ◽

10.1124/jpet.119.259150 ◽

2019 ◽

Vol 370 (3) ◽

pp. 360-368 ◽

Cited By ~ 3

Author(s):

Erin Burgunder ◽

John K. Fallon ◽

Nicole White ◽

Amanda P. Schauer ◽

Craig Sykes ◽

...

Keyword(s):

Lymph Nodes ◽

Viral Infection ◽

Nonhuman Primates ◽

Humanized Mice ◽

Drug Transporter ◽

Species Comparison ◽

Drug Concentrations ◽

Antiretroviral Drug ◽

Cross Species Comparison ◽

Transporter Expression

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Detection and quantification of Parascaris P-glycoprotein drug transporter expression with a novel mRNA hybridization technique

Veterinary Parasitology ◽

10.1016/j.vetpar.2019.02.002 ◽

2019 ◽

Vol 267 ◽

pp. 75-83 ◽

Cited By ~ 4

Author(s):

Jeba Jesudoss Chelladurai ◽

Matthew T. Brewer

Keyword(s):

Hybridization Technique ◽

Drug Transporter ◽

P Glycoprotein ◽

Transporter Expression ◽

Mrna Hybridization ◽

Detection And Quantification

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Bioavailability of the diterpenoid 14-deoxy-11,12-didehydroandrographolide in rats and up-regulation of hepatic drug-metabolizing enzyme and drug transporter expression

Phytomedicine ◽

10.1016/j.phymed.2019.152841 ◽

2019 ◽

Vol 61 ◽

pp. 152841 ◽

Cited By ~ 3

Author(s):

Chih-Ching Yen ◽

Yun-Ta Liu ◽

Ying-Jyan Lin ◽

Ya-Chen Yang ◽

Chien-Chih Chen ◽

...

Keyword(s):

Drug Transporter ◽

Hepatic Drug ◽

Drug Metabolizing Enzyme ◽

Metabolizing Enzyme ◽

Transporter Expression

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Kidney Ischemia/Reperfusion Injury Induces Changes in the Drug Transporter Expression at the Blood–Brain Barrier in vivo and in vitro

Frontiers in Physiology ◽

10.3389/fphys.2020.569881 ◽

2020 ◽

Vol 11 ◽

Author(s):

Malgorzata Burek ◽

Sandra Burmester ◽

Ellaine Salvador ◽

Kerstin Möller-Ehrlich ◽

Reinhard Schneider ◽

...

Keyword(s):

Reperfusion Injury ◽

Blood Brain Barrier ◽

Ischemia Reperfusion Injury ◽

Ischemia Reperfusion ◽

Brain Barrier ◽

Drug Transporter ◽

Blood Brain ◽

Transporter Expression

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Abstract A90: Dichloroacetate can overcome drug resistance via decreased ABC drug transporter expression and PDK2 inhibition

10.1158/1557-3125.metca15-a90 ◽

2016 ◽

Author(s):

Santhi Achuthan ◽

Richard Callaghan ◽

Anneke C. Blackburn

Keyword(s):

Drug Resistance ◽

Drug Transporter ◽

Transporter Expression

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Differential Regulation of Drug Transporter Expression by Hepatocyte Growth Factor in Primary Human Hepatocytes

Drug Metabolism and Disposition ◽

10.1124/dmd.109.028035 ◽

2009 ◽

Vol 37 (11) ◽

pp. 2228-2235 ◽

Cited By ~ 37

Author(s):

Marc Le Vee ◽

Valérie Lecureur ◽

Amélie Moreau ◽

Bruno Stieger ◽

Olivier Fardel

Keyword(s):

Growth Factor ◽

Hepatocyte Growth Factor ◽

Differential Regulation ◽

Human Hepatocytes ◽

Drug Transporter ◽

Primary Human Hepatocytes ◽

Hepatocyte Growth ◽

Transporter Expression

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Differential Regulation of Sinusoidal and Canalicular Hepatic Drug Transporter Expression by Xenobiotics Activating Drug-Sensing Receptors in Primary Human Hepatocytes

Drug Metabolism and Disposition ◽

10.1124/dmd.106.010033 ◽

2006 ◽

Vol 34 (10) ◽

pp. 1756-1763 ◽

Cited By ~ 219

Author(s):

Emilie Jigorel ◽

Marc Le Vee ◽

Claire Boursier-Neyret ◽

Yannick Parmentier ◽

Olivier Fardel

Keyword(s):

Differential Regulation ◽

Human Hepatocytes ◽

Drug Transporter ◽

Hepatic Drug ◽

Primary Human Hepatocytes ◽

Transporter Expression

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