Characterization of Human Cytochrome P450s Involved in the Bioactivation of Clozapine

2013 ◽  
Vol 41 (3) ◽  
pp. 651-658 ◽  
Author(s):  
Sanja Dragovic ◽  
Patrina Gunness ◽  
Magnus Ingelman-Sundberg ◽  
Nico P.E. Vermeulen ◽  
Jan N. M. Commandeur
Keyword(s):  
Cytochrome P450s ◽  
Human Cytochrome

Function of human cytochrome P450s: Characterization of the orphans

2005 ◽  
Vol 338 (1) ◽  
pp. 465-469 ◽  
Author(s):  
F. Peter Guengerich ◽  
Zhong-Liu Wu ◽  
Cheryl J. Bartleson
Keyword(s):  
Cytochrome P450s ◽  
Human Cytochrome

Characterization of Human Cytochrome P450s Involved in the Bioactivation of Tri-ortho-cresyl Phosphate (ToCP)

2015 ◽  
Vol 28 (4) ◽  
pp. 711-721 ◽  
Author(s):  
Jelle Reinen ◽  
Leyla Nematollahi ◽  
Alex Fidder ◽  
Nico P. E. Vermeulen ◽  
Daan Noort ◽  
...  
Keyword(s):  
Cytochrome P450s ◽  
Human Cytochrome

Characterization of mixtures of recombinant human cytochrome P450s as a screening model for metabolic stability in drug discovery

Xenobiotica ◽  
2002 ◽  
Vol 32 (9) ◽  
pp. 749-759 ◽  
Author(s):  
N. Hagen ◽  
A. K. Olsen ◽  
J. V. Andersen ◽  
J. Tjørnelund ◽  
S. H. Hansen
Keyword(s):  
Drug Discovery ◽  
Cytochrome P450s ◽  
Metabolic Stability ◽  
Screening Model ◽  
Human Cytochrome

Characterization of Diuron N-Demethylation by Mammalian Hepatic Microsomes and cDNA-Expressed Human Cytochrome P450 Enzymes

2007 ◽  
Vol 35 (9) ◽  
pp. 1634-1641 ◽  
Author(s):  
Khaled Abass ◽  
Petri Reponen ◽  
Miia Turpeinen ◽  
Jorma Jalonen ◽  
Olavi Pelkonen
Keyword(s):  
Cytochrome P450 ◽  
Cytochrome P450 Enzymes ◽  
Hepatic Microsomes ◽  
Human Cytochrome

Genotoxicity of tamoxifen epoxide and toremifene in human lymphoblastoid cells containing human cytochrome P450s

1994 ◽  
Vol 15 (1) ◽  
pp. 5-9 ◽  
Author(s):  
J. A. Styles ◽  
A. Davies ◽  
C. K. Lim ◽  
F. De Matteis ◽  
L. A. Stanley ◽  
...  
Keyword(s):  
Cytochrome P450s ◽  
Lymphoblastoid Cells ◽  
Human Cytochrome
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