scholarly journals Compartmentalization and Antiviral Effect of Efavirenz Metabolites in Blood Plasma, Seminal Plasma, and Cerebrospinal Fluid

2012 ◽  
Vol 41 (2) ◽  
pp. 422-429 ◽  
Author(s):  
Lindsay B. Avery ◽  
Jennifer L. VanAusdall ◽  
Craig W. Hendrix ◽  
Namandjé N. Bumpus
Author(s):  
Abhradip Majumder ◽  
Manjula Thakur ◽  
Mukesh Bhakat ◽  
Manorama Saha ◽  
Tushar Kumar Mohanty ◽  
...  

The effect of dietary supplementation of Cu and Zn on semen quality parameters and certain bio-chemicals parameters were evaluated in Murrah bulls. Twelve mature Murrah bulls (4-6 years of age) were divided into three groups (n=4) T1, T2, and T3 based on semen volume and concentration and were fed as per ICAR standard (2013). However, the animals were supplemented with 0%, 25%, and 50% Cu and Zn above the basal diet in T1, T2 and T3 groups, respectively for 180 days. Quantitative and qualitative characteristics of semen, blood and seminal plasma antioxidant status, blood and semen minerals (Cu, Zn, Ca and Mn) were determined in experimental Murrah bulls. Semen ejaculate volume (mL) increased in T2 and T3 while sperm concentration (million/mL), intact acrosome (%), HOST reacted spermatozoa (%) increased in T3 group compared to T1 and T2 groups. No difference was observed in mass motility, pH, live spermatozoa (%) in semen sexual behaviour except dismounting time which was decreased in T3 than T1 and T2 (plessthan0.05). SOD activity in blood plasma and LPO activity decreased in seminal plasma in both T2 and T3 groups than T1, whereas catalase activity did not show any significant difference. Cu and Zn supplementation in T2 group improved plessthan0.05) Zn level in blood and seminal plasma and Cu level in blood plasma only, but not in seminal plasma. Therefore, it can be concluded that supplementation of Zn and Cu at 50% above the recommended levels of ICAR (2013) improved the qualitative and quantitative attributes of semen in Murrah bulls.


1983 ◽  
Vol 19 (1) ◽  
pp. 725-729 ◽  
Author(s):  
R. Claus ◽  
D. Schopper ◽  
H.-G. Wagner

1983 ◽  
Vol 107 (1) ◽  
pp. 95-103 ◽  
Author(s):  
M. Morisawa ◽  
K. Suzuki ◽  
H. Shimizu ◽  
S. Morisawa ◽  
K. Yasuda

Spermatozoa of freshwater Cyprinidae (goldfish, carp, crucian carp and dace) remained immotile when the semen was diluted in solutions of NaCl, KCl, mannitol or glucose iso-osmolar to the seminal plasma (300 mosmol kg-1). The spermatozoa became motile in media containing these solutes if the osmolality was lower than that of the seminal plasma, suggesting that motility is suppressed by the osmolality of the seminal plasma in the sperm duct and initiated by a decrease of osmolality upon spawning into fresh water. Potassium was a major component of seminal plasma, having a concentration 20–30 times higher than that in the blood plasma in goldfish and carp. Sodium concentration in seminal plasma was lower than that in blood plasma. Potassium increased viability and speed of sperm movement at a concentration below that in the seminal plasma, whereas sodium and the nonelectrolytes were less effective. Potassium released with spermatozoa at spawning may therefore stimulate motility which has already been initiated by the decrease of osmolality.


2006 ◽  
Vol 52 (6) ◽  
pp. 805-810 ◽  
Author(s):  
Taiki MATSUOKA ◽  
Hiroko IMAI ◽  
Sadaki ASAKUMA ◽  
Hirohide KOHNO ◽  
Yutaka FUKUI

AIDS ◽  
2008 ◽  
Vol 22 (13) ◽  
pp. 1677-1679 ◽  
Author(s):  
Anne-Geneviève Marcelin ◽  
Roland Tubiana ◽  
Sidonie Lambert-Niclot ◽  
Gilles Lefebvre ◽  
Stéphanie Dominguez ◽  
...  

1999 ◽  
Vol 80 (5) ◽  
pp. 371-373
Author(s):  
L. I. Reikhert

The activity of superoxidismutase and catalase in thrombocytes as well as content of -tocopherol and -carotin in blood plasma and cerebrospinal fluid in 193 patients with ischemic insult are studied. Incompetence of the mechanisms of antioxidant defense correlating with gravity and outcome of ischemic insult is established. Depression of various links of the antioxidant defense system in blood plasma, thrombocytes and cerebrospinal fluid affects the gravity of clinical manifestations of the disease.


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