scholarly journals Thr302 Is the Site for the Covalent Modification of Human Cytochrome P450 2B6 Leading to Mechanism-Based Inactivation by tert-Butylphenylacetylene

2011 ◽  
Vol 39 (12) ◽  
pp. 2431-2439 ◽  
Author(s):  
Hsia-lien Lin ◽  
Haoming Zhang ◽  
Matthew J. Pratt-Hyatt ◽  
Paul F. Hollenberg
Keyword(s):  
Cytochrome P450 ◽  
Covalent Modification ◽  
Cytochrome P450 2B6 ◽  
Human Cytochrome

scholarly journals Structural and Thermodynamic Basis of (+)-α-Pinene Binding to Human Cytochrome P450 2B6

2013 ◽  
Vol 135 (28) ◽  
pp. 10433-10440 ◽  
Author(s):  
P. Ross Wilderman ◽  
Manish B. Shah ◽  
Hyun-Hee Jang ◽  
C. David Stout ◽  
James R. Halpert
Keyword(s):  
Cytochrome P450 ◽  
Cytochrome P450 2B6 ◽  
Human Cytochrome ◽  
Thermodynamic Basis

scholarly journals Comparison of In Vitro Metabolism of Ticlopidine by Human Cytochrome P450 2B6 and Rabbit Cytochrome P450 2B4

2010 ◽  
Vol 39 (3) ◽  
pp. 539-550 ◽  
Author(s):  
Jyothi C. Talakad ◽  
Manish B. Shah ◽  
Gregory S. Walker ◽  
Cathie Xiang ◽  
James R. Halpert ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
In Vitro Metabolism ◽  
Cytochrome P450 2B6 ◽  
Human Cytochrome ◽  
Cytochrome P450 2B4

scholarly journals Novel CAR-mediated Mechanism for Synergistic Activation of Two Distinct Elements within the Human Cytochrome P450 2B6 Gene in HepG2 Cells

2004 ◽  
Vol 280 (5) ◽  
pp. 3458-3466 ◽  
Author(s):  
Karen Swales ◽  
Satoru Kakizaki ◽  
Yukio Yamamoto ◽  
Kaoru Inoue ◽  
Kaoru Kobayashi ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Hepg2 Cells ◽  
Cytochrome P450 2B6 ◽  
Synergistic Activation ◽  
Human Cytochrome

scholarly journals Conformational Adaptation of Human Cytochrome P450 2B6 and Rabbit Cytochrome P450 2B4 Revealed upon Binding Multiple Amlodipine Molecules

Biochemistry ◽  
2012 ◽  
Vol 51 (37) ◽  
pp. 7225-7238 ◽  
Author(s):  
Manish B. Shah ◽  
P. Ross Wilderman ◽  
Jaime Pascual ◽  
Qinghai Zhang ◽  
C. David Stout ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Cytochrome P450 2B6 ◽  
Human Cytochrome ◽  
Cytochrome P450 2B4

Mechanism-Based Inhibition of Human Cytochrome P450 2B6 by Ticlopidine, Clopidogrel, and the Thiolactone Metabolite of Prasugrel

2008 ◽  
Vol 37 (3) ◽  
pp. 589-593 ◽  
Author(s):  
Yumi Nishiya ◽  
Katsunobu Hagihara ◽  
Takashi Ito ◽  
Masami Tajima ◽  
Shin-ichi Miura ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Cytochrome P450 2B6 ◽  
Human Cytochrome
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