Comparison of ATP-Binding Cassette Transporter Interactions with the Tyrosine Kinase Inhibitors Imatinib, Nilotinib, and Dasatinib

Marius Dohse; Christian Scharenberg; Suneet Shukla; Robert W. Robey; Thorsten Volkmann; John F. Deeken; Cornelia Brendel; Suresh V. Ambudkar; Andreas Neubauer; Susan E. Bates

doi:10.1124/dmd.109.031302

Comparison of ATP-Binding Cassette Transporter Interactions with the Tyrosine Kinase Inhibitors Imatinib, Nilotinib, and Dasatinib

Drug Metabolism and Disposition ◽

10.1124/dmd.109.031302 ◽

2010 ◽

Vol 38 (8) ◽

pp. 1371-1380 ◽

Cited By ~ 133

Author(s):

Marius Dohse ◽

Christian Scharenberg ◽

Suneet Shukla ◽

Robert W. Robey ◽

Thorsten Volkmann ◽

...

Keyword(s):

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitors ◽

Kinase Inhibitors ◽

Atp Binding ◽

Atp Binding Cassette Transporter ◽

Atp Binding Cassette

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Repositioning of Tyrosine Kinase Inhibitors as Antagonists of ATP-Binding Cassette Transporters in Anticancer Drug Resistance

Cancers ◽

10.3390/cancers6041925 ◽

2014 ◽

Vol 6 (4) ◽

pp. 1925-1952 ◽

Cited By ~ 35

Author(s):

Yi-Jun Wang ◽

Yun-Kai Zhang ◽

Rishil Kathawala ◽

Zhe-Sheng Chen

Keyword(s):

Drug Resistance ◽

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitors ◽

Anticancer Drug ◽

Kinase Inhibitors ◽

Atp Binding ◽

Atp Binding Cassette Transporters ◽

Anticancer Drug Resistance ◽

Atp Binding Cassette

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Tyrosine kinase inhibitors as modulators of ATP binding cassette multidrug transporters: substrates, chemosensitizers or inducers of acquired multidrug resistance?

Expert Opinion on Drug Metabolism & Toxicology ◽

10.1517/17425255.2011.562892 ◽

2011 ◽

Vol 7 (5) ◽

pp. 623-642 ◽

Cited By ~ 80

Author(s):

Anna Brózik ◽

Csilla Hegedüs ◽

Zsuzsa Erdei ◽

Tamás Hegedűs ◽

Csilla Özvegy-Laczka ◽

...

Keyword(s):

Multidrug Resistance ◽

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitors ◽

Kinase Inhibitors ◽

Atp Binding ◽

Multidrug Transporters ◽

Atp Binding Cassette

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1029 ATP-binding Cassette Transporter Inhibition by Tyrosine Kinase Inhibitor Nilotinib

European Journal of Cancer ◽

10.1016/s0959-8049(12)71644-1 ◽

2012 ◽

Vol 48 ◽

pp. S248

Author(s):

K. Quint ◽

P. Di Fazio ◽

R. Montalbano ◽

S. Lingelbach ◽

M. Ocker

Keyword(s):

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitor ◽

Kinase Inhibitor ◽

Atp Binding ◽

Atp Binding Cassette Transporter ◽

Atp Binding Cassette

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ATP-binding cassette transporter inhibition by tyrosine kinase inhibitor Nilotinib

Pancreatology ◽

10.1016/j.pan.2012.11.167 ◽

2012 ◽

Vol 12 (6) ◽

pp. 550-551

Author(s):

K. Quint ◽

F. Rückert ◽

M. Ocker

Keyword(s):

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitor ◽

Kinase Inhibitor ◽

Atp Binding ◽

Atp Binding Cassette Transporter ◽

Atp Binding Cassette

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Abstract 5139: Molecular docking exploration of potential RET tyrosine kinase inhibitors at non ATP-binding sites.

10.1158/1538-7445.am2013-5139 ◽

2013 ◽

Author(s):

Adrian C. Nicolescu ◽

Taranjit S. Gujral ◽

Jordan DS Zelt ◽

Lois M. Mulligan

Keyword(s):

Molecular Docking ◽

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitors ◽

Binding Sites ◽

Kinase Inhibitors ◽

Atp Binding

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Abstract 5462: Extracellular ATP promotes cancer cell drug resistance to tyrosine kinase inhibitors by competing for the ATP-binding site of tyrosine kinase

10.1158/1538-7445.am2015-5462 ◽

2015 ◽

Author(s):

Xuan Wang ◽

Yanrong Qian ◽

Yunsheng Li ◽

Xiaozhuo Chen

Keyword(s):

Drug Resistance ◽

Tyrosine Kinase ◽

Binding Site ◽

Tyrosine Kinase Inhibitors ◽

Cancer Cell ◽

Kinase Inhibitors ◽

Extracellular Atp ◽

Atp Binding ◽

Atp Binding Site

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The influence of tyrosine kinase inhibitors on term and preterm parturition in mice

Journal of the Society for Gynecologic Investigation ◽

10.1016/s1071-5576(97)86159-x ◽

1998 ◽

Vol 5 (1) ◽

pp. 60A-60A ◽

Cited By ~ 1

Author(s):

J MIJOVIC ◽

D OLSON ◽

T ZAKAR

Keyword(s):

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitors ◽

Kinase Inhibitors

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Review for "The landscape of BCR-ABL mutations in patients with Philadelphia chromosome-positive leukaemias in the era of second-generation tyrosine kinase inhibitors"

10.1002/hon.2721/v1/review1 ◽

2019 ◽

Author(s):

Mark Heaney

Keyword(s):

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitors ◽

Second Generation ◽

Kinase Inhibitors ◽

Philadelphia Chromosome ◽

Philadelphia Chromosome Positive

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Decision letter for "The landscape of BCR-ABL mutations in patients with Philadelphia chromosome-positive leukaemias in the era of second-generation tyrosine kinase inhibitors"

10.1002/hon.2721/v1/decision1 ◽

2019 ◽

Keyword(s):

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitors ◽

Second Generation ◽

Kinase Inhibitors ◽

Philadelphia Chromosome ◽

Philadelphia Chromosome Positive

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Side effects of tyrosine kinase inhibitors (TKIs) on bone remodelling

Klinische Pädiatrie ◽

10.1055/s-0032-1310478 ◽

2012 ◽

Vol 224 (03) ◽

Author(s):

JT Tauer ◽

A Ulmer ◽

LC Hofbauer ◽

M Suttorp

Keyword(s):

Side Effects ◽

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitors ◽

Kinase Inhibitors ◽

Bone Remodelling

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