Pharmacokinetic-Pharmacodynamic Modeling of Biomarker Response and Tumor Growth Inhibition to an Orally Available cMet Kinase Inhibitor in Human Tumor Xenograft Mouse Models

2008 ◽  
Vol 36 (7) ◽  
pp. 1267-1274 ◽  
Author(s):  
Shinji Yamazaki ◽  
Judith Skaptason ◽  
David Romero ◽  
Joseph H. Lee ◽  
Helen Y. Zou ◽  
...  
Keyword(s):  
Tumor Growth ◽  
Growth Inhibition ◽  
Mouse Models ◽  
Kinase Inhibitor ◽  
Human Tumor ◽  
Tumor Xenograft ◽  
Pharmacodynamic Modeling ◽  
Tumor Growth Inhibition ◽  
Human Tumor Xenograft ◽  
Biomarker Response

Abstract 5242: Bioluminescence imaging of radiation induced tumor growth inhibition in orthotopic mouse models

2010 ◽  
Author(s):  
Meridith Baugher ◽  
Matt Ziemke ◽  
Erin Trachet ◽  
William Elliott ◽  
Wilbur R. Leopold ◽  
...  
Keyword(s):  
Tumor Growth ◽  
Growth Inhibition ◽  
Mouse Models ◽  
Bioluminescence Imaging ◽  
Tumor Growth Inhibition ◽  
Radiation Induced

scholarly journals GSK1070916, a potent Aurora B/C kinase inhibitor with broad antitumor activity in tissue culture cells and human tumor xenograft models

2009 ◽  
Vol 8 (7) ◽  
pp. 1808-1817 ◽  
Author(s):  
Mary Ann Hardwicke ◽  
Catherine A. Oleykowski ◽  
Ramona Plant ◽  
Jamin Wang ◽  
Qiaoyin Liao ◽  
...  
Keyword(s):  
Tissue Culture ◽  
Antitumor Activity ◽  
Kinase Inhibitor ◽  
Human Tumor ◽  
Tumor Xenograft ◽  
Aurora B ◽  
Human Tumor Xenograft ◽  
Culture Cells ◽  
Tissue Culture Cells ◽  
Xenograft Models
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