Isolation of the UDP-Glucuronosyltransferase 1A3 and 1A4 Proximal Promoters and Characterization of Their Dependence on the Transcription Factor Hepatocyte Nuclear Factor 1α

Dione A. Gardner-Stephen; Peter I. Mackenzie

doi:10.1124/dmd.106.012203

Isolation of the UDP-Glucuronosyltransferase 1A3 and 1A4 Proximal Promoters and Characterization of Their Dependence on the Transcription Factor Hepatocyte Nuclear Factor 1α

Drug Metabolism and Disposition ◽

10.1124/dmd.106.012203 ◽

2006 ◽

Vol 35 (1) ◽

pp. 116-120 ◽

Cited By ~ 24

Author(s):

Dione A. Gardner-Stephen ◽

Peter I. Mackenzie

Keyword(s):

Transcription Factor ◽

Nuclear Factor ◽

Hepatocyte Nuclear Factor ◽

Hepatocyte Nuclear Factor 1Α ◽

Udp Glucuronosyltransferase ◽

Proximal Promoters

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Characterization of Human Pterin-4a-carbinolamine Dehydratase/Dimerization Cofactor of Hepatocyte Nuclear Factor-1α, and of the Cys81-mutant Involved in Hyperphenylalanincemia

Pteridines ◽

10.1515/pteridines.1995.6.3.123 ◽

1995 ◽

Vol 6 (3) ◽

pp. 123-125 ◽

Cited By ~ 2

Author(s):

Sandra Köster ◽

Beat Thöny ◽

Peter Macheroux ◽

Hans-Christoph Curtius ◽

Claus W. Heizmann ◽

...

Keyword(s):

Nuclear Factor ◽

Hepatocyte Nuclear Factor ◽

Hepatocyte Nuclear Factor 1Α

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Structure/Function Studies of Hepatocyte Nuclear Factor-1α, a Diabetes-Associated Transcription Factor

Biochemical and Biophysical Research Communications ◽

10.1006/bbrc.1999.1747 ◽

1999 ◽

Vol 266 (1) ◽

pp. 196-202 ◽

Cited By ~ 26

Author(s):

Qin Yang ◽

Kazuya Yamagata ◽

Koji Yamamoto ◽

Jun-ichiro Miyagawa ◽

Jun Takeda ◽

...

Keyword(s):

Transcription Factor ◽

Structure Function ◽

Nuclear Factor ◽

Hepatocyte Nuclear Factor ◽

Hepatocyte Nuclear Factor 1Α

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Characterization of the Human OATP-C (SLC21A6) Gene Promoter and Regulation of Liver-specific OATP Genes by Hepatocyte Nuclear Factor 1α

Journal of Biological Chemistry ◽

10.1074/jbc.m103988200 ◽

2001 ◽

Vol 276 (40) ◽

pp. 37206-37214 ◽

Cited By ~ 120

Author(s):

Diana Jung ◽

Bruno Hagenbuch ◽

Lionel Gresh ◽

Marco Pontoglio ◽

Peter J. Meier ◽

...

Keyword(s):

Gene Promoter ◽

Nuclear Factor ◽

Hepatocyte Nuclear Factor ◽

Hepatocyte Nuclear Factor 1Α

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Coordinate Regulation of the Human UDP-Glucuronosyltransferase 1A8, 1A9, and 1A10 Genes by Hepatocyte Nuclear Factor 1α and the Caudal-Related Homeodomain Protein 2

Molecular Pharmacology ◽

10.1124/mol.65.4.953 ◽

2004 ◽

Vol 65 (4) ◽

pp. 953-963 ◽

Cited By ~ 55

Author(s):

Philip A. Gregory ◽

Rikke H. Lewinsky ◽

Dione A. Gardner-Stephen ◽

Peter I. Mackenzie

Keyword(s):

Homeodomain Protein ◽

Nuclear Factor ◽

Hepatocyte Nuclear Factor ◽

Coordinate Regulation ◽

Hepatocyte Nuclear Factor 1Α ◽

Udp Glucuronosyltransferase

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The caudal-related homeodomain protein Cdx2 and hepatocyte nuclear factor 1α cooperatively regulate the UDP-glucuronosyltransferase 2B7 gene promoter

Pharmacogenetics and Genomics ◽

10.1097/01.fpc.0000215068.06471.35 ◽

2006 ◽

Vol 16 (7) ◽

pp. 527-536 ◽

Cited By ~ 18

Author(s):

Philip A. Gregory ◽

Dione A. Gardner-Stephen ◽

Anne Rogers ◽

Michael Z. Michael ◽

Peter I. Mackenzie

Keyword(s):

Gene Promoter ◽

Homeodomain Protein ◽

Nuclear Factor ◽

Hepatocyte Nuclear Factor ◽

Hepatocyte Nuclear Factor 1Α ◽

Udp Glucuronosyltransferase

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Molecular Cloning and Characterization of the HumanPED/PEA-15Gene Promoter Reveal Antagonistic Regulation by Hepatocyte Nuclear Factor 4α and Chicken Ovalbumin Upstream Promoter Transcription Factor II

Journal of Biological Chemistry ◽

10.1074/jbc.m803895200 ◽

2008 ◽

Vol 283 (45) ◽

pp. 30970-30979 ◽

Cited By ~ 24

Author(s):

Paola Ungaro ◽

Raffaele Teperino ◽

Paola Mirra ◽

Angela Cassese ◽

Francesca Fiory ◽

...

Keyword(s):

Transcription Factor ◽

Molecular Cloning ◽

Nuclear Factor ◽

Hepatocyte Nuclear Factor ◽

Factor Ii ◽

Upstream Promoter ◽

Hepatocyte Nuclear Factor 4Α ◽

Chicken Ovalbumin

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Identification and functional characterization of a novel mutation of hepatocyte nuclear factor-1α gene in a Korean family with MODY3

Diabetologia ◽

10.1007/s00125-003-1079-7 ◽

2003 ◽

Vol 46 (5) ◽

pp. 721-727 ◽

Cited By ~ 14

Author(s):

K.-A. Kim ◽

K. Kang ◽

Y.-I. Chi ◽

I. Chang ◽

M.-K. Lee ◽

...

Keyword(s):

Novel Mutation ◽

Functional Characterization ◽

Nuclear Factor ◽

Hepatocyte Nuclear Factor ◽

Korean Family ◽

Hepatocyte Nuclear Factor 1Α

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Identification and Characterization of Functional Hepatocyte Nuclear Factor 1‐Binding Sites in UDP‐Glucuronosyltransferase Genes

Methods in Enzymology - Phase II Conjugation Enzymes and Transport Systems ◽

10.1016/s0076-6879(05)00002-9 ◽

2005 ◽

pp. 22-46 ◽

Cited By ~ 9

Author(s):

Dione A. Gardner‐Stephen ◽

Philip A. Gregory ◽

Peter I. Mackenzie

Keyword(s):

Binding Sites ◽

Nuclear Factor ◽

Hepatocyte Nuclear Factor ◽

Udp Glucuronosyltransferase ◽

Nuclear Factor 1 ◽

Identification And Characterization

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Hepatocyte Nuclear Factor-1α Is a Causal Factor Responsible for Interindividual Differences in the Expression of UDP-Glucuronosyltransferase 2B7 mRNA in Human Livers

Drug Metabolism and Disposition ◽

10.1124/dmd.30.6.613 ◽

2002 ◽

Vol 30 (6) ◽

pp. 613-615 ◽

Cited By ~ 33

Author(s):

Kenji Toide ◽

Yoshiki Takahashi ◽

Hiroshi Yamazaki ◽

Yoshiaki Terauchi ◽

Toshihiko Fujii ◽

...

Keyword(s):

Causal Factor ◽

Nuclear Factor ◽

Hepatocyte Nuclear Factor ◽

Interindividual Differences ◽

Hepatocyte Nuclear Factor 1Α ◽

Udp Glucuronosyltransferase ◽

Human Livers

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Mutation P291fsinsC in the transcription factor hepatocyte nuclear factor-1alpha is dominant negative

Diabetes ◽

10.2337/diabetes.47.8.1231 ◽

1998 ◽

Vol 47 (8) ◽

pp. 1231-1235 ◽

Cited By ~ 19

Author(s):

K. Yamagata ◽

Q. Yang ◽

K. Yamamoto ◽

H. Iwahashi ◽

J. Miyagawa ◽

...

Keyword(s):

Transcription Factor ◽

Dominant Negative ◽

Nuclear Factor ◽

Hepatocyte Nuclear Factor

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