Acute Changes in Vitamin B6, Status in Endurance Athletes before and after a Marathon

1994 ◽  
Vol 4 (2) ◽  
pp. 154-165 ◽  
Author(s):  
Lothar Rokitzki ◽  
Andree N. Sagredos ◽  
Friedrich Reuß ◽  
Michael Büchner ◽  
Josef Keul

The vitamin status of 13 endurance athletes was determined by whole blood (microbiological) and urine 4-pyridoxic acid (4-PA) (HPLC), serum vitamin (pyridoxal, pyridoxol, pyridoxamin) (HPLC), and erythrocyte α- EGOT measurements with the aid of 7-day records. In addition, blood and serum samples and urine were collected before (Time A), directly after (Time B), and 2 hr after a marathon race (Time C). The total energy intake was 12,303 ± 3,464 Wday (34% fat, 48% carbohydrates, 14% protein). The vitamin intake, serum concentrations, α-EGOT value, and 4-PA excretion were higher than the reference values at Time A. Only the vitamin whole blood levels were below the normal level at Time A. The vitamin B, status of the athletes corresponded essentially to reference values obtained for untrained individuals. There was a mean loss of about 1 mg vitamin as a result of the marathon race. Vitamin supplementation does not appear necessary if a balanced diet is consumed.

2017 ◽  
Vol 5 (9) ◽  
pp. 187
Author(s):  
Mehmet Türkmen

This study was conducted to determine the acute changes after the 20 m shuttle run test in the biochemical parameters and heart rates of wrestlers competing in international competitions on a study population of 21 wrestlers. The mean age of participants was 24.14±2.01years, mean heights 176±0.06 cm, body weight 76.48±14.76 kg, MaxVO2 52.78±3.20 ml/kg/min, and mean BMI 24.44±2.63 kg/m2.20-meter run and sit-up test was applied to measure the MaxVO2 scores of included subjects. Heart rates were monitored using a Polar heart rate monitor before and after the tests. The blood samples that collected at the same time intervals from the vena cephalica were stored in tubes without anticoagulants. The samples were then centrifuged for 10 minutes at 5000 rpm to obtain serum samples, and analyzed. The data obtained were treated using SPSS 15.0 software.This study showed that there was a significant increase (p<0.05) in post-test glucose, HDL-cholesterol and urea concentrations compared to pre-test levels. While the post-test LDL cholesterol concentration was significantly reduced (p<0.05), acute changes in other biochemical parameters were found to be statistically insignificant (p>0.05).It can be concluded that mean glucose, HDL and urea were increased while LDL was reduced after the 20 m shuttle run test in wrestlers.


Author(s):  
N.V. BOGOLYUBOVA ◽  
I.V. GUSEV ◽  
R.A. RYKOV ◽  
N.A. KOMBAROVA

Для разработки референтных значений биохимических показателей, характеризующих нормальное течение обменных процессов, исследованы пробы сыворотки крови быков-производителей голштинской породы (n=102), разделенных на 4 группы по возрасту и содержащихся в условиях племпредприятия Московской области. В сыворотке крови определяли концентрацию общего белка, альбумина, мочевины, креатинина, активность аланинаминотрансферазы (АЛТ), аспартатаминотрансферазы (АСТ). Установлено, что с возрастом быков достоверно увеличивается содержание в крови общего белка. У животных 2—4 лет этот показатель увеличился на 11% (P<0,01), 4—6 лет — на 19,1% (P<0,01), более 6 лет — на 21,5% (P<0,001) по сравнению с быками до 2-летнего возраста. Это связано с повышением глобулиновой фракции. С возрастом быков в связи с увеличением их живой массы отмечалось повышение концентрации креатинина в крови, а также мочевины. У производителей 4—6-летнего возраста содержание мочевины в крови увеличивалось на 47,9% (P<0,001) по сравнению с быками до 2 лет. Повышение активности АСТ у быков-производителей с возрастом можно связать с повышенной нагрузкой на печень и сердечно-сосудистую систему в связи с их производственным использованием. Полученные данные о метаболическом профиле производителей разных возрастов помогут на практике проводить мониторинг и корректировку состояния животных, а также в разработке эталонных значений для оценки здоровья и уровня питания.Questions of the relationship of indicators of protein metabolism in the body of bulls with age can serve as accumulative material for the development of reference values of biochemical indicators characterizing the normal course of metabolic processes. The serum samples of the Holstein breeding bulls (n=102), divided into 4 groups by age and contained in the conditions of the “Head Center for the Reproduction of Farm Animals”, were investigated. The following parameters were determined in blood serum: concentration of total protein, albumin, urea, creatinine, activity of alanine aminotransferase (ALT), aspartate aminotransferase (AST). As a result of research, it has been established that with age, bulls reliably increase blood levels of total protein. In the 2—4 year old bulls, this indicator increased by 11% (P<0.01), 4-6 years old — by 19.1% (P<0.01), and over 6 years old — by 21.5% (P<0,001) compared with animals under 2 years. This was associated with an increase in the globulin fraction. With increasing age of the bulls, an increase in the concentration of creatinine in the blood was observed, which is associated with an increase in body weight of animals. Noted the increase in urea in the blood of the bulls with age. Thus, in the blood of bulls of 4—6 years of age, this indicator increased by 47.9% (P<0.001) as compared with analogues up to 2 years. An increase in AST activity in bulls with age can be associated with an increased load on the liver and the cardiovascular system due to their production use. The obtained data on the metabolic profile of the bulls of different ages will help in practice to monitor and adjust the condition of the animals and to develop reference values for assessing health and nutrition levels. Key


1989 ◽  
Vol 68 (5) ◽  
pp. 780-785 ◽  
Author(s):  
K.R. Snapp ◽  
D.B. Boyer ◽  
L.C. Peterson ◽  
C.W. Svare

We determined the exposure to mercury from dental amalgam by comparison of blood levels of mercury before and after removal of all amalgams from ten subjects. Baseline concentrations of mercury in whole blood were measured weekly for four to 18 weeks (median = 6.6 weeks) prior to removal. All amalgams were removed in a single appointment. The subjects had an average of 14 surfaces of amalgam, seven of which were occlusal surfaces. Weekly blood sampling was continued for five to 18 weeks (median=7.6 weeks) after the amalgams were removed. The mean baseline concentration of total mercury in whole blood of the ten subjects was 2.18 (SD = 0.90) ng Hgl mL before the amalgams were removed. The baseline mercury levels were related to the number of amalgam surfaces. The linear correlation coefficient was 0.724 with number of occlusal surfaces, and 0.433 with total number of surfaces. After removal of the amalgams, nine of the ten subjects exhibited a statistically significant decrease in blood mercury at the 95% level of confidence. The mean decrease in mercury was 1.13 (SD = 0.60) ng Hg/mL. The half-time for elimination of mercury from blood after amalgam removal was 30.2 (SD = 5.8) days. Removal of the amalgams provided an additional exposure of 1. 46 (SD = 1.17) ng HglmL that was rapidly cleared from the blood with a half-time of 2.9 days. The daily intake of mercury from amalgam in the subjects was estimated to be at least 1.3 μg.


2021 ◽  
Vol 9 (T3) ◽  
pp. 353-357
Author(s):  
Andi Jayalangkara Tanra ◽  
Herwina Sabaruddin ◽  
Kristian Liaury ◽  
Andi Alfian Zainuddin

AIM: This study aims to determine the effect of adjuvant Vitamin C on brain-derived neurotropic factors (BDNF) levels and improvement of negative symptoms in schizophrenic patients. METHODS: This study was conducted at Hasanuddin University Hospital and its affiliate with 60 schizophrenic patients (30 controls, 27 treatments, and three dropout patients). The ELISA sample examination method was used to examine blood levels of BDNF, and Vitamin C levels before and after administration of Vitamin C. In addition, the negative symptoms were measured using the PANSS score. RESULTS: There was a significant increase in BDNF levels in treatments group compared the control at 4th–8th weeks with p = 0.005 (4th week) and ≤0.0001 (<0.05) (8th week). The improvement in PANSS scores for negative symptoms in the treatment groups compared to the controls at the 2nd, 4th, and 8th weeks resulted in p = 0.042 (2nd week) and <0.0001 (4th–8th weeks). Furthermore, there was an increase in serum Vitamin C levels in the treatment groups with an initial average value = 4.762 and after 8 weeks = 148.155. Strong correlation between increased BDNF levels and improvement in negative symptoms on the PANSS score was found with p = 0.001 (4th week) and ≤0.0001 (8th week). CONCLUSION: The administration of Vitamin C significantly increases BDNF levels and improves the PANSS score for negative symptoms in the treatments compared to the control groups.


Nutrients ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 1963
Author(s):  
Małgorzata Żychowska ◽  
Rafał Rola ◽  
Andżelika Borkowska ◽  
Maja Tomczyk ◽  
Jakub Kortas ◽  
...  

Background: Vitamin D plays pleiotropic roles in the body and hence, changes in its metabolism and distribution during starvation could play an important role in the adaptive response to famine. We aimed to identify the responses of some vitamin D metabolites to 8 d of fasting and exercise. Methods: A repeated-measures design was implemented, in which 14 male volunteers fasted for 8 d and performed an exercise test before and after fasting. Serum samples were collected on day 1 after night fasting and after 8 d of complete food restriction, before and 1 h and 3 h after exercise. Results: After 8 d of fasting, compared with baseline values, serum 24,25(OH)2D3 and 3-epi-25(OH)D3 levels significantly increased; those of 25(OH)D3 and 1,25(OH)2D3 were unaffected; and those of 25(OH)D2 decreased. Exercise on the first day of fasting induced an increase in serum 3-epi-25(OH)D3 levels, while exercise performed after 8 d of fasting induced an increase in 25(OH)D3, 24,25(OH)2D3, 25(OH)D2, and 3-epi-25(OH)D3 levels. Conclusion: Increases in 24,25(OH)2D3 and 3-epi-25(OH)D3 levels imply that fasting stimulates vitamin D metabolism. The effects of exercise on serum vitamin D metabolites, which are most pronounced after fasting and in subjects with serum 25(OH)D3 above 25 ng/mL, support the notion that fasting and exercise augment vitamin D metabolism.


2019 ◽  
Vol 27 (2) ◽  
pp. 1397-1405 ◽  
Author(s):  
Aleksandar Stojsavljević ◽  
Jovana Jagodić ◽  
Ljiljana Vujotić ◽  
Slavica Borković-Mitić ◽  
Zorica Rašić-Milutinović ◽  
...  

2018 ◽  
Vol 2 (1) ◽  
Author(s):  
Sameerah Mustafa ◽  
Asal Tawfeeq ◽  
Hadeel Hasan

This study involved the collection of (90) samples of women serum which included (30) serum samples collected from women before menopause (reproductive women) in the age range of (22-43) years and were considered as (group A- control). While, (group B) included (30) serum samples collected from women using oral contraceptive pills between the ages of (22-43) years old. Whereas, another (30) serum samples were collected from women after menopause between the ages of (43-54) years and were considered as (group C). All of the collected serum samples were subjected to a number of serological and chemical tests for the measurement of (E2, HDL, LDL and Ca). Then, the obtained data were statistical analyzed and results showed a significant decrease (p˂ 0.05) in (E2 ,Ca and HDL) levels in menopausal women compared to that of the normal healthy controls. While, there were non-significant decrease (p> 0.05) in (E2, Ca and HDL) levels in women taking oral contraceptive when compared to the normal healthy controls. On the other hand, a significant increase (p˂ 0.05) was recorded in LDL level in menopausal women compared to that of the normal healthy controls whereas, no-significant increase (p˃ 0.05) in the LDL level in women taking oral contraceptives when compared to the control women.


2019 ◽  
Vol 26 (3) ◽  
pp. 227-234 ◽  
Author(s):  
Meriem Bencharif ◽  
Ibrahim Sersar ◽  
Maroua Bentaleb ◽  
Fatima Zohra Boutata ◽  
Youcef Benabbas

Abstract Background and aims: The diabetic exempted from fasting by religion, wishing or not to observe the fast, is exposed like any other during Ramadan to a change in lifestyle. The objective of this study was to highlight the effects of Ramadan fasting on diabetes. Material and methods: Multicentre study on 899 diabetics was carried to collect data on the behaviour of diabetics with regard to the fast of Ramadan, biochemicals and anthropometry parameters. Results. The sample consists of 541 diabetic fasters (DTMF) and 358 no fasters. The causes of interruption of fasting were: hypoglycemia (82.4%), dehydration (44.5%), hyperglycemia (12.6%), high blood pressure (13.7%), loss of consciousness (8.3%). The risk factors related to fasting for DTMF were the type of diabetes and gender. Discussion and modifications about dietary, blood glucose monitoring and nutritional education sessions showed a protective effect against the occurrence of hypo and hyperglycemia and loss of consciousness. Decreasing differences were noted for Hb1Ac, LDL and Total-Cholesterol between before and after Ramadan. The weight of DTMF decreased in post-Ramadan (p=0.0000). Conclusion. There is a need to consider regular preventive measures based on public information on the effects of diabetes related complications and the benefits of a balanced diet combined with regular physical activity in nutrition education sessions.


2019 ◽  
Vol 9 (o3) ◽  
Author(s):  
Suaad Muhssen Ghazi ◽  
Fatin Shallal Farhan

Vitamin D deficiency is common in women with polycystic ovarian syndrome. Vitamin D plays an important physiologic role in reproductive functions of ovarian follicular development and luteinization through altering anti-müllerian hormone signaling, follicular stimulating hormone activity and progesterone production in human granulose cells. Vitamin D is precipitated in adipose fat tissues, making it notable to be used for the body as a result; obese people with high body mass index are already highly expected to have low levels of serum vitamin D.


Author(s):  
Sanjeeva Kumar Goud T ◽  
Rahul Kunkulol

The present study was aimed to study the effect of Sublingual Vitamin D3 on Serum Vitamin D level in Vitamin D deficiency patients. This was a cross-sectional and interventional study. All the Vitamin D deficiency patients of age 18-60years and either gender, willing to participate in the study were included. Patients who had greater than 20 ng/ml were excluded from the study. The total number of participants in our study was 200, out of these 111 males and 89 females, the mean age in our study was 51.07 ± 7.39Yrs. All volunteers were given sublingual vitamin D3 (60,000IU) in six doses every fifteen days of follow up for 3 months. The subject’s serum 25(OH)D levels were estimated before and after the treatment of sublingual vitamin D3. There was a statistically significant difference in serum vitamin D3 level before 16.61±6.71 ng/ml and after 35.80±7.80 ng/ml after treatment with Sublingual Vitamin D3. Six doses of 60,000IU of Vitamin D3 sublingual route having improved the role of serum 25(OH)D levels in the treatment of Vitamin D3 deficiency patients.Keywords: Vitamin D3; Sublingual route


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