Long-chain dynamics in binary blends of monodisperse linear polymers

2006 ◽  
Vol 50 (1) ◽  
pp. 21-39 ◽  
Author(s):  
Seung Joon Park ◽  
Ronald G. Larson
Keyword(s):  
Linear Polymers ◽  
Binary Blends ◽  
Chain Dynamics ◽  
Long Chain

Tube Dilation and Reptation in Binary Blends of Monodisperse Linear Polymers

2004 ◽  
Vol 37 (2) ◽  
pp. 597-604 ◽  
Author(s):  
Seung Joon Park ◽  
Ronald G. Larson
Keyword(s):  
Linear Polymers ◽  
Binary Blends

scholarly journals Dynamic Dilution Effect in Binary Blends of Linear Polymers with Well-Separated Molecular Weights

2014 ◽  
Vol 47 (21) ◽  
pp. 7653-7665 ◽  
Author(s):  
E. van Ruymbeke ◽  
V. Shchetnikava ◽  
Y. Matsumiya ◽  
H. Watanabe
Keyword(s):  
Dilution Effect ◽  
Linear Polymers ◽  
Binary Blends ◽  
Molecular Weights

scholarly journals Self-Diffusion in Binary Blends of Cyclic and Linear Polymers

2008 ◽  
Vol 41 (19) ◽  
pp. 7239-7242 ◽  
Author(s):  
Gopinath Subramanian ◽  
Sachin Shanbhag
Keyword(s):  
Linear Polymers ◽  
Binary Blends ◽  
Self Diffusion

scholarly journals Long-chain polyphosphates impair SARS-CoV-2 infection and replication

2021 ◽  
Vol 14 (690) ◽  
pp. eabe5040
Author(s):  
Veronica Ferrucci ◽  
Dae-Young Kong ◽  
Fatemeh Asadzadeh ◽  
Laura Marrone ◽  
Angelo Boccia ◽  
...  
Keyword(s):  
Amino Acid ◽  
Limited Proteolysis ◽  
High Energy ◽  
Site Directed Mutagenesis ◽  
Linear Polymers ◽  
Amino Acid Residues ◽  
Human Nasal Epithelial Cells ◽  
Antiviral Activities ◽  
Long Chain

Inorganic polyphosphates (polyPs) are linear polymers composed of repeated phosphate (PO43−) units linked together by multiple high-energy phosphoanhydride bonds. In addition to being a source of energy, polyPs have cytoprotective and antiviral activities. Here, we investigated the antiviral activities of long-chain polyPs against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. In molecular docking analyses, polyPs interacted with several conserved amino acid residues in angiotensin-converting enzyme 2 (ACE2), the host receptor that facilitates virus entry, and in viral RNA-dependent RNA polymerase (RdRp). ELISA and limited proteolysis assays using nano– LC-MS/MS mapped polyP120 binding to ACE2, and site-directed mutagenesis confirmed interactions between ACE2 and SARS-CoV-2 RdRp and identified the specific amino acid residues involved. PolyP120 enhanced the proteasomal degradation of both ACE2 and RdRp, thus impairing replication of the British B.1.1.7 SARS-CoV-2 variant. We thus tested polyPs for functional interactions with the virus in SARS-CoV-2–infected Vero E6 and Caco2 cells and in primary human nasal epithelial cells. Delivery of a nebulized form of polyP120 reduced the amounts of viral positive-sense genomic and subgenomic RNAs, of RNA transcripts encoding proinflammatory cytokines, and of viral structural proteins, thereby presenting SARS-CoV-2 infection in cells in vitro.

Poly(vinylamine-co-N-isopropylacrylamide) linear polymer and hydrogels with tuned thermoresponsivity

Soft Matter ◽  
2020 ◽  
Vol 16 (28) ◽  
pp. 6549-6562 ◽  
Author(s):  
Thorsten Fischer ◽  
Dan E. Demco ◽  
Radu Fechete ◽  
Martin Möller ◽  
Smriti Singh
Keyword(s):  
Nmr Spectroscopy ◽  
Linear Polymer ◽  
Linear Polymers ◽  
Chain Dynamics ◽  
H Nmr

Poly(vinylamine-co-N-isopropylacrylamide) linear polymers and hydrogels with tuned thermoresponsivity have been synthetized. They morphology and chain dynamics where investigated by rheology and 1H NMR spectroscopy, relaxometry and diffusometry.

Photopolymerization-induced phase separation in binary blends of photocurable/linear polymers

Polymer ◽  
2002 ◽  
Vol 43 (9) ◽  
pp. 2845-2859 ◽  
Author(s):  
Kazutaka Murata ◽  
Jain Sachin ◽  
Hideki Etori ◽  
Takanori Anazawa
Keyword(s):  
Phase Separation ◽  
Linear Polymers ◽  
Binary Blends

Modeling the Rheology of Commercial Long Chain Branched Polymer Melts

2003 ◽  
Vol 804 ◽  
Author(s):  
Seung Joon Park ◽  
Ronald G. Larson
Keyword(s):  
Experimental Data ◽  
Hierarchical Model ◽  
Polymer Melts ◽  
Quantitative Agreement ◽  
Branched Polymers ◽  
Linear Polymers ◽  
Branched Polymer ◽  
Long Chain Branching ◽  
Wide Range ◽  
Long Chain

ABSTRACTThe predictions of a general “hierarchical model” for the rheology of general mixtures of linear and branched polymers are compared to experimental data for well-defined long-chain branched polymers. For a wide range of branched polymer melts, which include star-linear blends, H-polymers, and comb polymers, the predictions of the model agree well with experimental data. We apply the hierarchical model to metallocene-catalyzed polyethylenes (mPEs), in which the branched structures are generated by a Monte Carlo method based on the known reaction kinetics. The hierarchical model captures the shape of the curves of viscoelastic moduli vs. frequency of mPEs well and predicts accurately the effect of long chain branching on the linear viscoelastic properties. The quantitative agreement of the hierarchical model prediction with experimental data of well-defined long-chain branched polymers and mPEs shows that information on branching structure could be inferred from rheological measurements on combinatorial sets of mixtures of an unknown branched with different combinations of linear polymers.

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