Effect of pulse duration and repetition rate on burst wave lithotripsy stone fragmentation in vitro

2021 ◽  
Vol 150 (4) ◽  
pp. A332-A332
Author(s):  
Ga Won Kim ◽  
Christopher Hunter ◽  
Adam Maxwell ◽  
Bryan W. Cunitz ◽  
Michael R. Bailey ◽  
...  
Keyword(s):  
Pulse Duration ◽  
Repetition Rate ◽  
Stone Fragmentation

Factors Controlling Electropermeabilisation of Cell Membranes

2002 ◽  
Vol 1 (5) ◽  
pp. 319-327 ◽  
Author(s):  
M. P. Rols ◽  
M. Golzio ◽  
B. Gabriel ◽  
J. Teissié
Keyword(s):  
Cell Surface ◽  
Electric Field ◽  
Pulse Duration ◽  
Cell Membranes ◽  
Physical Parameters ◽  
Local Exchange ◽  
Physical Mechanisms ◽  
A Cell

Electric field pulses are a new approach for drug and gene delivery for cancer therapy. They induce a localized structural alteration of cell membranes. The associated physical mechanisms are well explained and can be safely controlled. A position dependent modulation of the membrane potential difference is induced when an electric field is applied to a cell. Electric field pulses with an overcritical intensity evoke a local membrane alteration. A free exchange of hydrophilic low molecular weight molecules takes place across the membrane. A leakage of cytosolic metabolites and a loading of polar drugs into the cytoplasm are obtained. The fraction of the cell surface which is competent for exchange is a function of the field intensity. The level of local exchange is strongly controlled by the pulse duration and the number of successive pulses. The permeabilised state is long lived. Its lifetime is under the control of the cumulated pulse duration. Cell viability can be preserved. Gene transfer is obtained but its mechanism is not a free diffusion. Plasmids are electrophoretically accumulated against the permeabilised cell surface and form aggregates due to the field effect. After the pulses, several steps follow: translocation to the cytoplasm, traffic to the nucleus and expression. Molecular structural and metabolic changes in cells remain mostly poorly understood. Nevertheless, while most studies were established on cells in culture ( in vitro), recent experiments show that similar effects are obtained on tissue ( in vivo). Transfer remains controlled by the physical parameters of the electrical treatment.

Pulsed infrared laser irradiation of biological tissue: effect of pulse duration and repetition rate

1993 ◽  
Author(s):  
E. Duco Jansen ◽  
Ravi K. Chundru ◽  
Salim A. Samanani ◽  
Todd A. Tibbetts ◽  
Ashley J. Welch
Keyword(s):  
Laser Irradiation ◽  
Pulse Duration ◽  
Biological Tissue ◽  
Repetition Rate ◽  
Infrared Laser ◽  
Infrared Laser Irradiation ◽  
Tissue Effect

Experimental Study on Hundred-Watt Output Power High Repetition Rate Narrow Pulse Duration Fiber Lasers

2009 ◽  
Vol 36 (2) ◽  
pp. 281-284
Author(s):  
李尧 Li Yao ◽  
朱辰 Zhu Chen ◽  
王雄飞 Wang Xiongfei ◽  
林佶翔 Lin Jixiang ◽  
赵鸿 Zhao Hong
Keyword(s):  
Experimental Study ◽  
Pulse Duration ◽  
Output Power ◽  
Repetition Rate ◽  
Fiber Lasers ◽  
High Repetition Rate ◽  
High Repetition

Dependence of stimulated Brillouin scattering in pulsed fiber amplifier on signal linewidth, pulse duration, and repetition rate

2012 ◽  
Vol 10 (11) ◽  
pp. 111402-111405 ◽  
Author(s):  
Rongtao Su Rongtao Su ◽  
Pu Zhou Pu Zhou ◽  
Xiaolin Wang Xiaolin Wang ◽  
Hu Xiao Hu Xiao ◽  
Xiaojun Xu Xiaojun Xu
Keyword(s):  
Pulse Duration ◽  
Repetition Rate ◽  
Brillouin Scattering ◽  
Stimulated Brillouin Scattering ◽  
Fiber Amplifier ◽  
Stimulated Brillouin

Dual-frequency setting for urinary stone fragmentation during shock wave lithotripsy: an in vitro study

Urolithiasis ◽  
2019 ◽  
Vol 48 (4) ◽  
pp. 369-375
Author(s):  
Christopher S. Han ◽  
Joel M. Vetter ◽  
Robert Endicott ◽  
Michael Chevinsky ◽  
Affan Zafar ◽  
...  
Keyword(s):  
Shock Wave ◽  
Shock Wave Lithotripsy ◽  
In Vitro Study ◽  
Urinary Stone ◽  
Vitro Study ◽  
Dual Frequency ◽  
Stone Fragmentation

Ytterbium-doped fiber amplifier with tunable repetition rate and pulse duration

Laser Physics ◽  
2010 ◽  
Vol 20 (8) ◽  
pp. 1738-1743 ◽  
Author(s):  
J. Swiderski ◽  
D. Dorosz ◽  
M. Skorczakowski ◽  
W. Pichola
Keyword(s):  
Pulse Duration ◽  
Repetition Rate ◽  
Fiber Amplifier
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