How does temporal diffusion affect the ongoing precedence effect?

1. In most natural environments, sound waves from a single source will reach a listener through both direct and reflected paths. Sound traveling the direct path arrives first, and determines the perceived location of the source despite the presence of reflections from many different locations. This phenomenon is called the "law of the first wavefront" or "precedence effect." The time at which the reflection is first perceived as a separately localizable sound defines the end of the precedence window and is called "echo threshold." The precedence effect represents an important property of the auditory system, the neural basis for which has only recently begun to be examined. Here we report the responses of single neurons in the inferior colliculus (IC) and superior olivary complex (SOC) of the unanesthetized rabbit to a sound and its simulated reflection. 2. Stimuli were pairs of monaural or binaural clicks delivered through earphones. The leading click, or conditioner, simulated a direct sound, and the lagging click, or probe, simulated a reflection. Interaural time differences (ITDs) were introduced in the binaural conditioners and probes to adjust their simulated locations. The probe was always set at the neuron's best ITD, whereas the conditioner was set at the neuron's best ITD or its worst ITD. To measure the time course of the effects of the conditioner on the probe, we examined the response to the probe as a function of the conditioner-probe interval (CPI). 3. When IC neurons were tested with conditioners and probes set at the neuron's best ITD, the response to the probe as a function of CPI had one of two forms: early-low or early-high. In early-low neurons the response to the probe was initially suppressed but recovered monotonically at longer CPIs. Early-high neurons showed a nonmonotonic recovery pattern. In these neurons the maximal suppression did not occur at the shortest CPIs, but rather after a period of less suppression. Beyond this point, recovery was similar to that of early-low neurons. The presence of early-high neurons meant that the overall population was never entirely suppressed, even at short CPIs. Taken as a whole. CPIs for 50% recovery of the response to the probe among neurons ranged from 1 to 64 ms with a median of approximately 6 ms. 4. The above results are consistent with the time course of the precedence effect for the following reasons. 1) The lack of complete suppression at any CPI is compatible with behavioral results that show the presence of a probe can be detected even at short CPIs when it is not separately localizable. 2) At a CPI corresponding to echo threshold for human listeners (approximately 4 ms CPI) there was a considerable response to the probe, consistent with it being heard as a separately localizable sound at this CPI. 3) Full recovery for all neurons required a period much longer than that associated with the precedence effect. This is consistent with the relatively long time required for conditioners and probes to be heard with equal loudness. 5. Conditioners with either the best ITD or worst ITD were used to determine the effect of ITD on the response to the probe. The relative amounts of suppression caused by the two ITDs varied among neurons. Some neurons were suppressed about equally by both types of conditioners, others were suppressed more by a conditioner with the best ITD, and still others by a conditioner with the worst ITD. Because the best ITD and worst ITD presumably activate different pathways, these results suggest that different neurons receive a different balance of inhibition from different sources. 6. The recovery functions of neurons not sensitive to ITDs were similar to those of ITD-sensitive, neurons. This suggests that the time course of suppression may be common among different IC populations. 7. We also studied neurons in the SOC. Although many showed binaural interactions, none were sensitive to ITDs. Thus the response of this population may not be

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Sensitivity of Auditory Cortical Neurons to the Locations of Leading and Lagging Sounds

Journal of Neurophysiology ◽

10.1152/jn.00580.2004 ◽

2005 ◽

Vol 94 (2) ◽

pp. 979-989 ◽

Cited By ~ 17

Author(s):

Brian J. Mickey ◽

John C. Middlebrooks

Keyword(s):

Unit Activity ◽

Cortical Neurons ◽

Precedence Effect ◽

Related Information ◽

Sound Levels ◽

Transmission Of Information ◽

Discrete Responses ◽

Temporal Firing ◽

Spike Patterns ◽

Awake Cats

We recorded unit activity in the auditory cortex (fields A1, A2, and PAF) of anesthetized cats while presenting paired clicks with variable locations and interstimulus delays (ISDs). In human listeners, such sounds elicit the precedence effect, in which localization of the lagging sound is impaired at ISDs ≲10 ms. In the present study, neurons typically responded to the leading stimulus with a brief burst of spikes, followed by suppression lasting 100–200 ms. At an ISD of 20 ms, at which listeners report a distinct lagging sound, only 12% of units showed discrete lagging responses. Long-lasting suppression was found in all sampled cortical fields, for all leading and lagging locations, and at all sound levels. Recordings from awake cats confirmed this long-lasting suppression in the absence of anesthesia, although recovery from suppression was faster in the awake state. Despite the lack of discrete lagging responses at delays of 1–20 ms, the spike patterns of 40% of units varied systematically with ISD, suggesting that many neurons represent lagging sounds implicitly in their temporal firing patterns rather than explicitly in discrete responses. We estimated the amount of location-related information transmitted by spike patterns at delays of 1–16 ms under conditions in which we varied only the leading location or only the lagging location. Consistent with human psychophysical results, transmission of information about the leading location was high at all ISDs. Unlike listeners, however, transmission of information about the lagging location remained low, even at ISDs of 12–16 ms.

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Dynamic Temporal Processing of Nonspeech Acoustic Information by Children With Specific Language Impairment

Journal of Speech Language and Hearing Research ◽

10.1044/jshr.3903.510 ◽

1996 ◽

Vol 39 (3) ◽

pp. 510-517 ◽

Cited By ~ 10

Author(s):

Jane C. Visto ◽

Jerry L. Cranford ◽

Rosalind Scudder

Keyword(s):

Language Learning ◽

Language Impairment ◽

Specific Language Impairment ◽

Precedence Effect ◽

Complex Sound ◽

Specific Language ◽

Acoustic Information ◽

Rapid Changes ◽

Spectral Components ◽

Normal Language

The present study investigated whether children with specific language impairment (SLI) differed from children with normal language learning in their ability to process binaural temporal information. The SLI group was matched with peers of the same chronological age, as well as peers with similar language age. All three subject groups were tested with measures of complex sound localization involving the precedence effect phenomenon. Subjects were required to track the apparent motion of a “moving” fused auditory image (FAI). Movement of the FAI was simulated by varying the delay incrementally between pairs of clicks presented, one each, from two matched loudspeakers placed on opposite sides of the child’s head. With this task, the SLI subjects’ performances were found to be similar to their language age-matched but chronologically younger peers. Both groups exhibited tracking skills that were statistically poorer than that of the chronologically age-matched group. Additional tests indicated this effect was not due to differences in motoric tracking abilities nor to the SLI subjects’ abilities to perceive small binaural time cues. Thus, children with SLI appear to be impaired in their ability to use binaural acoustic information in a dynamic ongoing fashion. The requirements for processing such nonlinguistic acoustic information in a “dynamic and ongoing” fashion may be similar to those involved in the ongoing processing of rapid changes in the temporal and spectral components of the speech chain.

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