scholarly journals Pharmaceutical otoprotection strategies to prevent impulse noise-induced hearing loss

2019 ◽  
Vol 146 (5) ◽  
pp. 3790-3799 ◽  
Author(s):  
Eric C. Bielefeld ◽  
Ryan T. Harrison ◽  
J. Riley DeBacker
2006 ◽  
Vol 126 (11) ◽  
pp. 1140-1147 ◽  
Author(s):  
Maoli Duan ◽  
Zhiqiang Chen ◽  
Jianxin Qiu ◽  
Mats Ulfendahl ◽  
Göran Laurell ◽  
...  

2003 ◽  
Vol 113 (4) ◽  
pp. 2196-2196
Author(s):  
Jeffrey S. Vipperman ◽  
Mary M. Prince ◽  
Angela M. Flamm

2010 ◽  
pp. 1432-1434
Author(s):  
Syed M. Ahmed ◽  
Tar-Ching Aw

For clinical purposes, noise is measured in decibels weighted according to the sensitivity of the human ear (dB(A)). Regardless of source, the effects of overexposure to noise are similar. Initially there is a temporary threshold shift, where reversibility of hearing loss is possible with removal away from further noise. Permanent threshold shift occurs following prolonged and/or intense exposure, with poor prospects for improvement of hearing. The classical audiogram for noise-induced hearing loss shows a 4 kHz dip. Prevention is by reducing exposure to noise at source, and in the United Kingdom a limit for exposure has been set at 87 dB(A) averaged over an 8-h day or 140 dB(A) for any instantaneous impulse noise....


2021 ◽  
Author(s):  
Guo-wei Qi ◽  
Lei Shi ◽  
Han-dai Qin ◽  
Yuhua Zhu ◽  
Qing-qing Jiang ◽  
...  

Abstract Objectives: This study was designed to determine the morphology changes of noise-induced hidden hearing loss (NIHHL). Method: Fifteen guinea pigs were divided into three groups: noise-induced hidden hearing loss (NIHHL) group, noise-induced hearing loss (NIHL) group, and normal control group. For the noise-induced hidden hearing loss group, the guinea pigs were exposed to 15 times of impulse noise at one time. For the noise-induced hearing loss group, the animals were exposed to a total of 200 times of impulse noise in two times, and the time interval is 24 hours. Auditory brain response (ABR) was tested before, immediately, 24h, 1week, and one month after noise exposure to evaluate cochlear physiology changes. One month after noise exposure, all guinea pigs in three groups were sacrificed, and basement membranes were carefully dissected immediately after ABR tests. The cochlea samples were observed by transmission electron microscopy (TEM) to found out the monograph changes. Result: The ABR results showed that 15 times of impulse noise exposure could cause NIHHL in guinea pigs and 200 times could cause completely hearing loss. Impulse noise exposure could cause a dramatic increase in chondriosome in the inner hair cell. The structures of ribbon synapses and heminodes were also obviously impaired compared to the normal group. The nerve fibers and myelin sheaths remained intact after impulse noise exposure. Conclusion: This research revealed for the first time that impulse noise could cause hidden hearing loss, and the changes in inner hair cells, ribbon synapse, and heminode all played a vital role in the pathogenesis of hidden hearing loss.


1988 ◽  
Vol 105 (5-6) ◽  
pp. 558-563 ◽  
Author(s):  
J. Ylikoski ◽  
J. Juntunen ◽  
E. Matikainen ◽  
M. Ylikoski ◽  
M. Ojala

2011 ◽  
Vol 6 (1) ◽  
pp. 38 ◽  
Author(s):  
Haim Gavriel ◽  
Abraham Shulman ◽  
Alfred Stracher ◽  
Haim Sohmer

2005 ◽  
Vol 125 (3) ◽  
pp. 235-243 ◽  
Author(s):  
Richard Kopke ◽  
Eric Bielefeld ◽  
Jianzhong Liu ◽  
Jiefu Zheng ◽  
Ronald Jackson ◽  
...  

Author(s):  
Jennifer Tufts

Loud music and noisy hobbies are part of our cultural landscape. These activities can be enjoyed with minimal risk to hearing if a few commonsense guidelines are followed. Educating clients about risks and protective strategies will empower them to make informed decisions about their hearing health that best reflect their values and priorities. In this article, the author covers essential information to avoiding noise-induced hearing loss, writing in easily accessible language to better help clinicians convey this information to their clients.


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