scholarly journals Structural constitutive modeling of the anisotropic mechanical properties of human vocal fold lamina propria

2019 ◽  
Vol 145 (6) ◽  
pp. EL476-EL482
Author(s):  
Zhaoyan Zhang
Keyword(s):  
Mechanical Properties ◽  
Lamina Propria ◽  
Constitutive Modeling ◽  
Vocal Fold ◽  
Anisotropic Mechanical Properties

scholarly journals Dynamic Response of Thermally Bonded Bicomponent Fibre Nonwovens

2011 ◽  
Vol 70 ◽  
pp. 405-409 ◽  
Author(s):  
Emrah Demirci ◽  
Memiş Acar ◽  
Behnam Pourdeyhimi ◽  
Vadim V. Silberschmidt
Keyword(s):  
Mechanical Properties ◽  
Dynamic Response ◽  
Fibre Diameter ◽  
Orientation Distribution ◽  
Nonwoven Fabric ◽  
Woven Fabrics ◽  
Core Material ◽  
Finite Element Software ◽  
Anisotropic Mechanical Properties ◽  
Fibre Matrix

Having a unique microstructure, nonwoven fabrics possess distinct mechanical properties, dissimilar to those of woven fabrics and composites. This paper aims to introduce a methodology for simulating a dynamic response of core/sheath-type thermally bonded bicomponent fibre nonwovens. The simulated nonwoven fabric is treated as an assembly of two regions with distinct mechanical properties. One region - the fibre matrix – is composed of non-uniformly oriented core/sheath fibres acting as link between bond points. Non-uniform orientation of individual fibres is introduced into the model in terms of the orientation distribution function in order to calculate the structure’s anisotropy. Another region – bond points – is treated in simulations as a deformable bicomponent composite material, composed of the sheath material as its matrix and the core material as reinforcing fibres with random orientations. Time-dependent anisotropic mechanical properties of these regions are assessed based on fibre characteristics and manufacturing parameters such as the planar density, core/sheath ratio, fibre diameter etc. Having distinct anisotropic mechanical properties for two regions, dynamic response of the fabric is modelled in the finite element software with shell elements with thicknesses identical to those of the bond points and fibre matrix.

scholarly journals Anisotropic Mechanical Properties of Living Cells Revealed by Integrated Spinning Disk Confocal and Atomic Force Microscopy

2018 ◽  
Vol 114 (3) ◽  
pp. 513a
Author(s):  
Yuri M. Efremov ◽  
Mirian Velay-Lizancos ◽  
Daniel M. Suter ◽  
Pablo D. Zavattieri ◽  
Arvind Raman
Keyword(s):  
Mechanical Properties ◽  
Atomic Force Microscopy ◽  
Living Cells ◽  
Force Microscopy ◽  
Atomic Force ◽  
Spinning Disk ◽  
Anisotropic Mechanical Properties

Orientation of bone mineral and its role in the anisotropic mechanical properties of bone—Transverse anisotropy

1989 ◽  
Vol 22 (2) ◽  
pp. 157-164 ◽  
Author(s):  
Naoki Sasaki ◽  
Norio Matsushima ◽  
Tetsu Ikawa ◽  
Hidemi Yamamura ◽  
Akeharu Fukuda
Keyword(s):  
Mechanical Properties ◽  
Bone Mineral ◽  
Transverse Anisotropy ◽  
Anisotropic Mechanical Properties

Reinke's Edema: Phonatory Mechanisms and Management Strategies

1997 ◽  
Vol 106 (7) ◽  
pp. 533-543 ◽  
Author(s):  
Steven M. Zeitels ◽  
Glenn W. Bunting ◽  
Robert E. Hillman ◽  
Traci Vaughn
Keyword(s):  
Lamina Propria ◽  
Fundamental Frequency ◽  
Vocal Fold ◽  
Management Strategies ◽  
Vocal Folds ◽  
Vocal Fold Vibration ◽  
Reinke’S Edema ◽  
Subglottal Pressure ◽  
Almost All ◽  
Superficial Lamina

Reinke's edema (RE) has been associated typically with smoking and sometimes with vocal abuse, but aspects of the pathophysiology of RE remain unclear. To gain new insights into phonatory mechanisms associated with RE pathophysiology, weused an integrated battery of objective vocal function tests to analyze 20 patients (19 women) who underwent phonomicrosurgical resection. Preoperative stroboscopic examinations demonstrated that the superficial lamina propria is distended primarily on the superior vocal fold surface. Acoustically, these individuals have an abnormally low average speaking fundamental frequency (123 Hz), and they generate abnormally high average subglottal pressures (9.7 cm H20). The presence of elevated aerodynamic driving pressures reflects difficulties in producing vocal fold vibration that are most likely the result of mass loading associated with RE, and possibly vocal hyperfunction. Furthermore, it is hypothesized that in the environment of chronic glottal mucositis secondary to smoking and reflux, the cephalad force on the vocal folds by the subglottal driving pressure contributes to the superior distention of the superficial lamina propria. Surgical reduction of the volume of the superficial lamina propria resulted in a significant elevation in fundamental frequency (154 Hz) and improvement in perturbation measures. In almost all instances, both the clinician and the patient perceived the voice as improved. However, these patients continued to generate elevated subglottal pressure (probably a sign of persistent hyperfunction) that was accompanied by visually observed supraglottal strain despite the normalsized vocal folds. This finding suggests that persistent hyperfunctional vocal behaviors may contribute to postsurgical RE recurrence if therapeutic strategies are not instituted to modify such behavior.

Immunocytochemical Study of Proteoglycans in Vocal Folds

1996 ◽  
Vol 105 (1) ◽  
pp. 6-11 ◽  
Author(s):  
Agnieszka S. Pawlak ◽  
Elizabeth Hammond ◽  
Thomas Hammond ◽  
Steven D. Gray
Keyword(s):  
Chondroitin Sulfate ◽  
Lamina Propria ◽  
Vocal Fold ◽  
Keratan Sulfate ◽  
Vocal Folds ◽  
Basement Membrane Zone ◽  
Immunocytochemical Study ◽  
Frozen Sections ◽  
Intense Staining ◽  
Immunocytochemical Techniques

We evaluated the proteoglycan composition of normal vocal folds using immunocytochemical techniques. Frozen sections of 14 normal cadaveric vocal folds were obtained within 12 hours of death and sectioned immediately. Vocal fold sections were stained with antibodies against keratan sulfate, chondroitin sulfate, heparan sulfate proteoglycan (HSPG), decorin, and hyaluronate receptor. We found that the lamina propria has diffuse staining of fibrillar components with keratan sulfate and decorin. Intense staining was observed in the vocal ligament area with keratan sulfate. The HSPG was localized to the basement membrane zone. Chondroitin sulfate, HSPG, and hyaluronate receptor were detected in the cytoplasm of interstitial cells with immunocytochemical characteristics of macrophages. The keratan sulfate distribution suggests that fibromodulin may be significant in normal vocal folds. Production of HSPG and probably versican occurs in macrophages and fibroblasts in the lamina propria.

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