Direct measurement of nuclear diameter with high-frequency ultrasound (10–100 MHz) for breast cancer detection

2018 ◽  
Vol 143 (3) ◽  
pp. 1801-1801 ◽  
Author(s):  
Timothy E. Doyle ◽  
Jessica E. Carlson ◽  
Nicole Cowan ◽  
Garrett Wagner
Keyword(s):  
Breast Cancer ◽  
Direct Measurement ◽  
Cancer Detection ◽  
High Frequency ◽  
Breast Cancer Detection ◽  
High Frequency Ultrasound ◽  
Nuclear Diameter ◽  
Frequency Ultrasound

Utah Valley University/Huntsman Cancer Institute Collaborative Breast Cancer Study: High-frequency ultrasound for margin assessments

2014 ◽  
Vol 135 (4) ◽  
pp. 2179-2179
Author(s):  
J. Andrew Chappell ◽  
Janeese E. Stiles ◽  
Leigh A. Neumayer ◽  
Rachel E. Factor ◽  
Timothy E. Doyle
Keyword(s):  
Breast Cancer ◽  
High Frequency ◽  
High Frequency Ultrasound ◽  
Cancer Study ◽  
Breast Cancer Study ◽  
Frequency Ultrasound

High-frequency ultrasound (20–80 MHz) for analyzing breast cancer surgical margins: A 73-patient clinical study

2015 ◽  
Vol 138 (3) ◽  
pp. 1745-1746
Author(s):  
Amy A. LaFond ◽  
Caitlin Carter ◽  
Robyn K. Omer ◽  
Rachel E. Factor ◽  
Leigh A. Neumayer ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Clinical Study ◽  
High Frequency ◽  
Surgical Margins ◽  
High Frequency Ultrasound ◽  
Frequency Ultrasound

Breast Edema in Patients Undergoing Breast-Conserving Treatment for Breast Cancer: Assessment via High Frequency Ultrasound

2007 ◽  
Vol 13 (3) ◽  
pp. 266-273 ◽  
Author(s):  
Christopher R. Wratten ◽  
Peter C. O?Brien ◽  
Christopher S. Hamilton ◽  
Dana Bill ◽  
Jan Kilmurray ◽  
...  
Keyword(s):  
Breast Cancer ◽  
High Frequency ◽  
High Frequency Ultrasound ◽  
Breast Conserving Treatment ◽  
Frequency Ultrasound

Reproducibility of high-frequency ultrasonic signals in breast cancer detection

2014 ◽  
Vol 135 (4) ◽  
pp. 2179-2179
Author(s):  
A. Mackay Breivik ◽  
Andrew J. Marshall ◽  
Timothy E. Doyle
Keyword(s):  
Breast Cancer ◽  
Cancer Detection ◽  
High Frequency ◽  
Breast Cancer Detection ◽  
Ultrasonic Signals

Direct Measurement of Basilar Membrane Motion Using Pulsed-Wave Doppler High-Frequency Ultrasound

2011 ◽  
Author(s):  
Z. Torbatian ◽  
P. Garland ◽  
R. B. A. Adamson ◽  
M. Bance ◽  
J. A. Brown ◽  
...  
Keyword(s):  
Direct Measurement ◽  
High Frequency ◽  
Basilar Membrane ◽  
High Frequency Ultrasound ◽  
Pulsed Wave Doppler ◽  
Frequency Ultrasound

TMPRSS2: ERG expression in prostate cancer—Imaging and clinicopathological correlations.

2020 ◽  
Vol 38 (6_suppl) ◽  
pp. 284-284
Author(s):  
Vittorio Fasulo ◽  
Massimo Lazzeri ◽  
Marinella Corbetta ◽  
Marco Paciotti ◽  
Davide Maffei ◽  
...  
Keyword(s):  
Cancer Detection ◽  
High Frequency ◽  
High Frequency Ultrasound ◽  
Rt Pcr ◽  
Fusion Biopsy ◽  
Right Lobe ◽  
Biopsy Methods ◽  
Prostate Cancers ◽  
The Right ◽  
Frequency Ultrasound

284 Background: The TMPRSS2:ERG gene fusion (T:E) is found in up to 70% of prostate cancers (PCa) and results in androgen dependent overexpression of ERG, promoting tumor growth. The early identification of T:E may be helpful even in low-risk PCa. Although T:E can be non-invasively detected in urine, its correlation with new imaging tools (MRI and high-frequency ultrasound) and clinical outcome remains vague.This study investigates T:E expression in patients scheduled for random/software-assisted MRI or micro-ultrasound (29Mhz) fusion biopsy. Methods: This is a prospective cohort study in patients with suspected PCa enrolled between 2016 and 2019, approved by local authorities with Prot. N. 336/19, 14/05/2019. Patients underwent systematic US-guided biopsy, plus targeted biopsy if they had ³1 suspicious lesion (PI-RADS V.2 >2) at mpMRI or PRIMUS >2 at MICRO-US. For each patient, 1 prostatic core from the highest PI-RADS or PRIMUS lesion was collected for T:E analysis (a core from the right lobe in negative patients). Histological analyses were performed by experienced genitourinary pathologists. RNA was extracted from a dedicated fresh biopsy and RT-PCR was performed with different primer couples to detect the most frequent T:E fusions. All amplified products were checked by sequencing. Results: The cohort consists of 92 patients (median PSA 7.13 ng/ml, IQR 5.25-11.04 - average age 65ys), 81 with a diagnosis of PCa after biopsy. mpMRI was performed on 63 (68.5%) patients and was positive in 58 (92%), who underwent fusion biopsy. T:E fusion transcripts were detected in 23.5% of individuals with a diagnosis of PCa. Among patients positive for T:E, those analyzed by MRI were 100% positive (73% PI-RADS ≥4), those analyzed by MICRO-US were 83% positive. Sensitivity of the T:E assay for any PCa was 23.5%, specificity 100%, with negative and positive predicting values of 15% and 100%. There was no correlation between T:E and family history, PSA, PIRADS, PRI-MUS and Gleason score. Conclusions: Our finding showed a 100% of specificity making T:E an attractive tool for early cancer detection. In the future, identification of T:E in semen could represent a screening test for clinical stratification of patients with suspected PCa.

Molecular subtyping of breast cancer in vitro using high-frequency ultrasound

2013 ◽  
Vol 134 (5) ◽  
pp. 4216-4216
Author(s):  
Janeese E. Stiles ◽  
Laurel A. Thompson ◽  
Mandy H. Marvel ◽  
Janice E. Sugiyama ◽  
Timothy E. Doyle
Keyword(s):  
Breast Cancer ◽  
High Frequency ◽  
High Frequency Ultrasound ◽  
Molecular Subtyping ◽  
Frequency Ultrasound
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