Laboratory mice can behaviorally discriminate between natural and synthetic ultrasonic vocalizations

2017 ◽  
Vol 141 (5) ◽  
pp. 3715-3715
Author(s):  
Anastasiya Kobrina ◽  
Laurel A. Screven ◽  
Elena J. Mahrt ◽  
Micheal L. Dent ◽  
Christine Portfors
Keyword(s):  
Ultrasonic Vocalizations ◽  
Laboratory Mice ◽  
Natural And Synthetic

Ultrasonic vocalizations in laboratory mice

2016 ◽  
Vol 140 (4) ◽  
pp. 3299-3299
Author(s):  
Kali Burke ◽  
Laurel A. Screven ◽  
Micheal L. Dent
Keyword(s):  
Ultrasonic Vocalizations ◽  
Laboratory Mice

scholarly journals Spontaneous social communication in laboratory mice - placing ultrasonic vocalizations in their behavioral context

2020 ◽  
Author(s):  
Elodie Ey ◽  
Fabrice de Chaumont ◽  
Thomas Bourgeron
Keyword(s):  
Social Interactions ◽  
Social Communication ◽  
Natural Habitat ◽  
Ultrasonic Vocalizations ◽  
Laboratory Mice ◽  
Behavioral Context ◽  
Phenotypic Marker ◽  
Males And Females ◽  
Context Specific ◽  
High Level

SummaryIn their natural habitat, mice interact and communicate to regulate major functions, such as reproduction, group coordination, and protection. Nevertheless, little is currently known about their spontaneous emission of ultrasonic vocalizations (USVs), despite their broad use as a phenotypic marker in mouse models of neuropsychiatric disorders. Here, we investigated mouse spontaneous communication by coupling automatic recording, segmentation, and analysis of USVs to the tracking of complex behaviors. We continuously recorded undisturbed same-sex pairs of C57BL/6J males and females at 5 weeks and 3 and 7 months of age over three days. Males emitted only a few short USVs, mainly when isolated from their conspecific, whereas females emitted a high number of USVs, especially when engaged in intense dynamic social interactions. The context-specific use of call types and acoustic variations emerged with increasing age. The emission of USVs also reflected a high level of excitement in social interactions. Finally, mice lacking Shank3, a synaptic protein associated with autism, displayed atypical USV usage and acoustic structure, which did not appear in classical protocols, highlighting the importance of studying spontaneous communication. The methods are freely available for the research community (https://usv.pasteur.cloud).

Discrimination of natural from synthetic ultrasonic vocalizations by laboratory mice

2016 ◽  
Vol 140 (4) ◽  
pp. 3299-3299
Author(s):  
Anastasiya Kobrina ◽  
Laurel Screven ◽  
Micheal Dent
Keyword(s):  
Ultrasonic Vocalizations ◽  
Laboratory Mice

Semi-synthesis as a tool for broadening the health applications of bioactive olive secoiridoids: a critical review

2021 ◽  
Author(s):  
Manuela Oliverio ◽  
Monica Nardi ◽  
Maria Luisa Di Gioia ◽  
Paola Costanzo ◽  
Sonia Bonacci ◽  
...  
Keyword(s):  
Critical Review ◽  
Natural Compounds ◽  
Effective Strategy ◽  
Synthetic Analogues ◽  
Health Applications ◽  
Natural And Synthetic

Semi-synthesis is an effective strategy to obtain both natural and synthetic analogues of the olive secoiridoids, starting from easy accessible natural compounds.

Review of Natural and synthetic tyrosinase inhibitors

Planta Medica ◽  
2011 ◽  
Vol 77 (12) ◽  
Author(s):  
F Namjooyan ◽  
H Moosavi ◽  
A Taherian
Keyword(s):  
Tyrosinase Inhibitors ◽  
Natural And Synthetic

Natural and synthetic indirubins as potent and selective inhibitors of the protozoan parasite Leishmania donovani

Planta Medica ◽  
2007 ◽  
Vol 73 (09) ◽  
Author(s):  
E Xingi ◽  
D Smirlis ◽  
S Bisti ◽  
V Myrianthopoulos ◽  
P Magiatis ◽  
...  
Keyword(s):  
Leishmania Donovani ◽  
Protozoan Parasite ◽  
Selective Inhibitors ◽  
Parasite Leishmania ◽  
Natural And Synthetic

THE AUTORADIOGRAPHIC DISTRIBUTION PATTERN AFTER ADMINISTRATION OF DIETHYLSTILBOESTROL COMPARED WITH THAT OF NATURAL OESTROGENS

1963 ◽  
Vol 43 (4) ◽  
pp. 561-570 ◽  
Author(s):  
Gösta Bengtsson ◽  
Sven Ullberg
Keyword(s):  
Distribution Pattern ◽  
Adrenal Cortex ◽  
Natural Compounds ◽  
Ovarian Follicles ◽  
Interstitial Tissue ◽  
Specific Accumulation ◽  
Natural And Synthetic

ABSTRACT The distribution in mice of 14C- and 3H-diethylstilboestrol has been investigated autoradiographically. The results have been compared with those which have been previously reported for natural oestrogens. Many similarities have been demonstrated between the synthetic and natural compounds. Thus a specific accumulation has been observed in the endometrium, the granulosa layer of large ovarian follicles, the adrenal cortex. the interstitial tissue of the testes, and the hypophysis. Natural and synthetic oestrogens differ widely concerning the penetration into and the distribution within the foetus.

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