High frequency ultrafast flow and strain imaging in the carotid bifurcation: An ex vivo phantom study

2016 ◽  
Vol 140 (4) ◽  
pp. 3029-3029
Author(s):  
Anne E. Saris ◽  
Stein Fekkes ◽  
Maartje M. Nillesen ◽  
Hendrik H. Hansen ◽  
Chris L. de Korte
2018 ◽  
Vol 73 ◽  
pp. 233-237 ◽  
Author(s):  
Kaj Gijsbertse ◽  
André Sprengers ◽  
Hamid Naghibi Beidokhti ◽  
Maartje Nillesen ◽  
Chris de Korte ◽  
...  

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Pavel Jurak ◽  
Laura R. Bear ◽  
Uyên Châu Nguyên ◽  
Ivo Viscor ◽  
Petr Andrla ◽  
...  

AbstractThe study introduces and validates a novel high-frequency (100–400 Hz bandwidth, 2 kHz sampling frequency) electrocardiographic imaging (HFECGI) technique that measures intramural ventricular electrical activation. Ex-vivo experiments and clinical measurements were employed. Ex-vivo, two pig hearts were suspended in a human-torso shaped tank using surface tank electrodes, epicardial electrode sock, and plunge electrodes. We compared conventional epicardial electrocardiographic imaging (ECGI) with intramural activation by HFECGI and verified with sock and plunge electrodes. Clinical importance of HFECGI measurements was performed on 14 patients with variable conduction abnormalities. From 3 × 4 needle and 108 sock electrodes, 256 torso or 184 body surface electrodes records, transmural activation times, sock epicardial activation times, ECGI-derived activation times, and high-frequency activation times were computed. The ex-vivo transmural measurements showed that HFECGI measures intramural electrical activation, and ECGI-HFECGI activation times differences indicate endo-to-epi or epi-to-endo conduction direction. HFECGI-derived volumetric dyssynchrony was significantly lower than epicardial ECGI dyssynchrony. HFECGI dyssynchrony was able to distinguish between intraventricular conduction disturbance and bundle branch block patients.


2019 ◽  
Vol 45 (7) ◽  
pp. 1675-1690
Author(s):  
Stein Fekkes ◽  
Hendrik H.G. Hansen ◽  
Jan Menssen ◽  
Anne E.C.M. Saris ◽  
Chris L. de Korte

Sensors ◽  
2021 ◽  
Vol 21 (7) ◽  
pp. 2275
Author(s):  
Hae Gyun Lim ◽  
Hyung Ham Kim ◽  
Changhan Yoon

High-frequency ultrasound (HFUS) imaging has emerged as an essential tool for pre-clinical studies and clinical applications such as ophthalmic and dermatologic imaging. HFUS imaging systems based on array transducers capable of dynamic receive focusing have considerably improved the image quality in terms of spatial resolution and signal-to-noise ratio (SNR) compared to those by the single-element transducer-based one. However, the array system still suffers from low spatial resolution and SNR in out-of-focus regions, resulting in a blurred image and a limited penetration depth. In this paper, we present synthetic aperture imaging with a virtual source (SA-VS) for an ophthalmic application using a high-frequency convex array transducer. The performances of the SA-VS were evaluated with phantom and ex vivo experiments in comparison with the conventional dynamic receive focusing method. Pre-beamformed radio-frequency (RF) data from phantoms and excised bovine eye were acquired using a custom-built 64-channel imaging system. In the phantom experiments, the SA-VS method showed improved lateral resolution (>10%) and sidelobe level (>4.4 dB) compared to those by the conventional method. The SNR was also improved, resulting in an increased penetration depth: 16 mm and 23 mm for the conventional and SA-VS methods, respectively. Ex vivo images with the SA-VS showed improved image quality at the entire depth and visualized structures that were obscured by noise in conventional imaging.


2019 ◽  
Vol 66 (12) ◽  
pp. 3426-3435
Author(s):  
Fang-Yi Lay ◽  
Pei-Yu Chen ◽  
Hsiang-Fan Cheng ◽  
Yu-Min Kuo ◽  
Chih-Chung Huang

2017 ◽  
Vol 141 (5) ◽  
pp. 3492-3492
Author(s):  
Christine E. Dalton ◽  
Zachary A. Coffman ◽  
Garrett Wagner ◽  
Timothy E. Doyle

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Kornelia Schuetzenberger ◽  
Martin Pfister ◽  
Alina Messner ◽  
Vanessa Froehlich ◽  
Gerhard Garhoefer ◽  
...  

Abstract Optical coherence tomography (OCT) and high-frequency ultrasound (HFUS), two established imaging modalities in the field of dermatology, were evaluated and compared regarding their applicability for visualization of skin tissue morphology and quantification of murine intradermal structures. The accuracy and reproducibility of both methods were assessed ex vivo and in vivo using a standardized model for intradermal volumes based on injected soft tissue fillers. OCT revealed greater detail in skin morphology, allowing for detection of single layers due to the superior resolution. Volumetric data measured by OCT (7.9 ± 0.3 μl) and HFUS (7.7 ± 0.5 μl) were in good agreement and revealed a high accuracy when compared to the injected volume of 7.98 ± 0.8 µl. In vivo, OCT provided a higher precision (relative SD: 26% OCT vs. 42% HFUS) for the quantification of intradermal structures, whereas HFUS offered increased penetration depth enabling the visualization of deeper structures. A combination of both imaging technologies might be valuable for tumor assessments or other dermal pathologies in clinical settings.


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