scholarly journals Tone-burst auditory brainstem response wave V latencies in normal-hearing and hearing-impaired ears

2015 ◽  
Vol 138 (5) ◽  
pp. 3210-3219 ◽  
Author(s):  
James D. Lewis ◽  
Judy Kopun ◽  
Stephen T. Neely ◽  
Kendra K. Schmid ◽  
Michael P. Gorga
Keyword(s):  
Auditory Brainstem Response ◽  
Tone Burst ◽  
Auditory Brainstem ◽  
Normal Hearing ◽  
Hearing Impaired ◽  
Brainstem Response

Effects of Different Electrode Configurations on the Narrow Band Level-Specific CE-Chirp and Tone-Burst Auditory Brainstem Response at Multiple Intensity Levels and Frequencies in Subjects With Normal Hearing

2018 ◽  
Vol 27 (3) ◽  
pp. 294-305
Author(s):  
Ahmad Aidil Arafat Dzulkarnain ◽  
Siti Aisyah Abdullah ◽  
Muhammad Amar Mohd Ruzai ◽  
Siti Hajra Mu'minah Noor Ibrahim ◽  
Nur Farah Aida Anuar ◽  
...  
Keyword(s):  
Auditory Brainstem Response ◽  
Narrow Band ◽  
Tone Burst ◽  
Auditory Brainstem ◽  
Normal Hearing ◽  
Brainstem Response

Glutathione Ester But Not Glutathione Protects Against Cisplatin-Induced Ototoxicity in a Rat Model

2003 ◽  
Vol 14 (03) ◽  
pp. 124-133 ◽  
Author(s):  
Kathleen C.M. Campbell ◽  
Deb L. Larsen ◽  
Robert P. Meech ◽  
Leonard P. Rybak ◽  
Larry F. Hughes
Keyword(s):  
Auditory Brainstem Response ◽  
Outer Hair Cell ◽  
Tone Burst ◽  
Auditory Brainstem ◽  
Control Group ◽  
Brainstem Response ◽  
Group A ◽  
Direct Administration ◽  
Response Thresholds ◽  
Para Determinar

Glutathione (GSH) provides an important antioxidant and detoxification pathway. We tested to determine if direct administration of GSH or GSH ester could reduce cisplatin- (CDDP) induced ototoxicity. We tested eight groups of five rats each: a control group, a group receiving 16 mg/kg ip CDDP infused over 30 minutes, and six groups receiving either GSH or GSH ester at 500, 1000, or 1500 mg/kg intraperitoneally 30 minutes prior to 16 mg/kg CDDP. Auditory brainstem response thresholds were measured for click and tone-burst stimuli at baseline and 3 days later. Outer hair cell (OHC) loss was measured for the apical, middle and basal turns. The 500 mg/kg GSH ester reduced hearing loss and OHC loss, but protection decreased as dosage increased, suggesting possible toxicity. GSH was not significantly protective. The best GSH ester protection was less than we have previously reported with D-methionine. El glutatión (GSH) brinda una importante vía antioxidante y de cetoxificación. Realizamos una prueba para determinar si la administración directa de GSH o del éster de GSH podía reducir la ototoxicidad inducida por cisplatino (CDDP). Hicimos una evaluación en ocho grupos de cinco ratas cada uno: un grupo control, un grupo que recibió CDDP intraperitoneal a 16 mg/kg en una ínfusión durante 30 minutos y seis grupos que recibieron intraperitonealmente GSH o el éster de GSH a 500, 1000 o 1500 mg/kg, 30 minutos antes del CDDP a 16 mg/kg. Se midieron umbrales de respuestas auditivas del tallo cerebral tanto para clicks como para bursts tonales, al inicio y 3 días después. La pérdida de células ciliadas externas (OHC) fue establecida a nivel de las vueltas apical, media y basal. La dosis de 500 mg/kg de éster de GSH redujo la hipoacusia y la pérdida de OHC, pero la protección disminuyó conforme la dosis se incrementó, sugiriendo una posible toxicidad. EL GSH no resultó significativamente protector. El mejor efecto protector del éster de GSH fue menor que el previamente reportado con D-Metionina.

scholarly journals The Vestibular-Auditory Interaction for Auditory Brainstem Response to Low Frequencies

2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
Seyede Faranak Emami ◽  
Nasrin Gohari
Keyword(s):  
Auditory Brainstem Response ◽  
Tone Burst ◽  
Auditory Brainstem ◽  
Case Control ◽  
Vestibular Evoked Myogenic Potentials ◽  
Medical Sciences ◽  
Low Frequencies ◽  
Control Research ◽  
Brainstem Response ◽  
Vestibular Assessment

Since saccular projection is sound sensitive, the objective is to investigate the possibility that the saccular projections may contribute to auditory brainstem response to 500 HZ tone burst (ABR500 HZ). During the case-control research, twenty healthy controls compared to forty selected case groups as having chronic and resistant BPPV were evaluated in the audiology department of Hamadan University of Medical Sciences (Hamadan, Iran). Assessment is comprised of audiologic examinations, cervical vestibular evoked myogenic potentials (cVEMPs), and ABR500 HZ. We found that forty affected ears of BPPV patients with decreased vestibular excitability as detected by abnormal cVEMPs had abnormal results in ABR500 HZ, whereas unaffected ears presented normal findings. Multiple comparisons of mean p13, n23 latencies, and peak-to-peak amplitudes between three groups (affected, unaffected, and healthy ears) were significant. In conclusion, the saccular nerves can be projective to auditory bundles and interact with auditory brainstem response to low frequencies. Combine the cVEMPs and ABR500 HZ in battery approach tests of vestibular assessment and produce valuable data for judgment on the site of lesion. Regarding vestibular cooperation for making of wave V, it is reasonable that the term of ABR500 HZ is not adequate and the new term or vestibular-auditory brainstem response to 500 HZ tone burst is more suitable.

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