scholarly journals Characterization of material properties of soft solid thin layers with acoustic radiation force and wave propagation

2015 ◽  
Vol 138 (4) ◽  
pp. 2499-2507 ◽  
Author(s):  
Matthew W. Urban ◽  
Ivan Z. Nenadic ◽  
Bo Qiang ◽  
Miguel Bernal ◽  
Shigao Chen ◽  
...  
2009 ◽  
Vol 54 (13) ◽  
pp. 4089-4112 ◽  
Author(s):  
Bojan B Guzina ◽  
Kairat Tuleubekov ◽  
Dalong Liu ◽  
Emad S Ebbini

2018 ◽  
Vol 8 ◽  
pp. 5 ◽  
Author(s):  
Harshavardhan Nagolu ◽  
Sudhakar Kattoju ◽  
Chidambaranathan Natesan ◽  
Meera Krishnakumar ◽  
Sunil Kumar

Objective: The purpose of the study is to investigate the usefulness of acoustic radiation force impulse (ARFI) elastography in the characterization of focal solid liver lesions as benign, malignant, or metastatic using ARFI two-dimensional (2D) imaging and ARFI quantification (shear wave velocities [SWVs]). Materials and Methods: Sixty lesions were included in this study. The lesions were classified into three groups: Group I included benign lesions (n = 25), Group II included malignant lesions (n = 27), and Group III included metastatic lesions (n = 8). ARFI elastography was performed in all these patients using a Siemens ACUSON S 2000™ ultrasound machine. Stiffness and size of the lesions were assessed on ARFI 2D images in correlation with B-mode ultrasound images. SWVs were obtained in these lesions for the quantification of stiffness. Results: In ARFI 2D images, malignant lesions were predominantly stiffer and larger, while benign lesions were softer and similar in size (P < 0.05). The mean SWVs in benign, malignant, and metastatic lesions were 1.30 ± 0.35 m/s, 2.93 ± 0.75 m/s, and 2.77 ± 0.90 m/s, respectively. The area under receiver operating characteristic curve of SWV for differentiating benign from malignant lesions was 0.877, suggesting fair accuracy (95% confidence interval: 0.777–0.976); with a cutoff value of 2 m/s, showing sensitivity: 92%; specificity: 96%; positive predictive value: 96%; negative predictive value: 93% (P < 0.05). Statistically significant difference exists in SWV of benign and malignant or metastatic lesions. Conclusion: ARFI elastography with 2D imaging and quantification might be useful in the characterization of benign and malignant liver lesions.


2016 ◽  
Vol 83 (7) ◽  
Author(s):  
Fengxian Xin ◽  
Tianjian Lu

Acoustic radiation force generated by two counterpropagating acoustic waves in a thin layer of soft material can induce large deformation, and hence can be applied to design acoustomechanical actuators. Owing to the sensitivity of wave propagation to material geometry, the change of layer thickness may enhance wave propagation and acoustic radiation force, causing a jumping larger deformation, i.e., snap-through instability. Built upon the basis of strong elliptic condition, we develop a generalized theoretical method to evaluate the acoustomechanical stability of soft material actuators. We demonstrate that acoustomechanical instability occurs when the true tangential stiffness matrix ceases to be positive definite. Our results show that prestresses can not only enhance significantly the acoustomechanical stability of the soft material layer but also amplify its actuation stretch in thickness direction.


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