Doppler ultrasound detection of shear waves remotely induced in tissue phantoms by focused ultrasound

2000 ◽  
Vol 108 (5) ◽  
pp. 2549-2550 ◽  
Author(s):  
Evgen A. Barannik ◽  
Sergii A. Girnyk ◽  
Volodymyr V. Tovstiak ◽  
Armen P. Sarvazyan
Ultrasonics ◽  
2002 ◽  
Vol 40 (1-8) ◽  
pp. 849-852 ◽  
Author(s):  
E.A. Barannik ◽  
A. Girnyk ◽  
V. Tovstiak ◽  
A.I. Marusenko ◽  
S.Y. Emelianov ◽  
...  

2020 ◽  
Vol 142 (3) ◽  
Author(s):  
Charlotte A. Guertler ◽  
Ruth J. Okamoto ◽  
Jake A. Ireland ◽  
Christopher P. Pacia ◽  
Joel R. Garbow ◽  
...  

Abstract This paper describes a new method for estimating anisotropic mechanical properties of fibrous soft tissue by imaging shear waves induced by focused ultrasound (FUS) and analyzing their direction-dependent speeds. Fibrous materials with a single, dominant fiber direction may exhibit anisotropy in both shear and tensile moduli, reflecting differences in the response of the material when loads are applied in different directions. The speeds of shear waves in such materials depend on the propagation and polarization directions of the waves relative to the dominant fiber direction. In this study, shear waves were induced in muscle tissue (chicken breast) ex vivo by harmonically oscillating the amplitude of an ultrasound beam focused in a cylindrical tissue sample. The orientation of the fiber direction relative to the excitation direction was varied by rotating the sample. Magnetic resonance elastography (MRE) was used to visualize and measure the full 3D displacement field due to the ultrasound-induced shear waves. The phase gradient (PG) of radially propagating “slow” and “fast” shear waves provided local estimates of their respective wave speeds and directions. The equations for the speeds of these waves in an incompressible, transversely isotropic (TI), linear elastic material were fitted to measurements to estimate the shear and tensile moduli of the material. The combination of focused ultrasound and MR imaging allows noninvasive, but comprehensive, characterization of anisotropic soft tissue.


1996 ◽  
Vol 100 (4) ◽  
pp. 2647-2647 ◽  
Author(s):  
Valery Andreev ◽  
Yury Pishalnikov ◽  
Oleg Rudenko ◽  
Oleg Sapozhnikov ◽  
Vladimir Dmitriev ◽  
...  

2020 ◽  
Author(s):  
Hossein Salahshoor ◽  
Mikhail G. Shapiro ◽  
Michael Ortiz

ABSTRACTFocused ultrasound (FUS) is an established technique for non-invasive surgery and has recently attracted considerable attention as a potential method for non-invasive neuromodulation. While the pressure waves generated by FUS in this context have been extensively studied, the accompanying shear waves are often neglected due to the relatively high shear compliance of soft tissues. However, in bony structures such as the skull, acoustic pressure can also induce significant shear waves that could propagate outside the ultrasound focus. Here, we investigate wave propagation in the human cranium by means of a finite-element model that accounts for the anatomy, elasticity and viscoelasticity of the skull and brain. We show that, when a region on the frontal lobe is subjected to FUS, the skull acts as a wave guide for shear waves, resulting in their propagation to off-target structures such as the cochlea. This effect helps explain the off-target auditory responses observed during neuromodulation experiments and informs the development of mitigation and sham control strategies.


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