Rheo-acoustical study of the shear disruption of reversible aggregates. Ultrasound scattering from concentrated suspensions of red cell aggregates

2000 ◽  
Vol 107 (3) ◽  
pp. 1715-1726 ◽  
Author(s):  
L. Haider ◽  
P. Snabre ◽  
M. Boynard
Keyword(s):  
Cell Aggregates ◽  
Red Cell ◽  
Concentrated Suspensions ◽  
Ultrasound Scattering ◽  
Acoustical Study

Prevention and dispersion of contrast media induced red cell aggregates

1990 ◽  
Vol 31 (3) ◽  
pp. 309-314
Author(s):  
R. Raininko ◽  
S. -L. Ylinen
Keyword(s):  
Contrast Media ◽  
Cell Aggregates ◽  
Red Cell

Effects on Erythrocyte Aggregation and Blood Coagulation from Iohexol Solutions with and without Sodium Chloride

1995 ◽  
Vol 36 (2) ◽  
pp. 204-209
Author(s):  
C.-M. Chai ◽  
T. Almén ◽  
P. Aspelin ◽  
L. Bååth
Keyword(s):  
Sodium Chloride ◽  
Blood Coagulation ◽  
Glucose Solution ◽  
Cell Aggregation ◽  
Test Solution ◽  
Erythrocyte Aggregation ◽  
Cell Aggregates ◽  
Red Cell ◽  
Red Blood Cell Aggregation ◽  
Osmotic Effects

Solutions of the nonionic monomeric contrast medium iohexol (300 mg I/ml) with and without added NaCl were investigated for effects on red blood cell aggregation and blood coagulation. Three volumes of a test solution were mixed in test tubes with one volume of human blood. During 30 min samples of the mixture were taken for investigation. Six test solutions were used: 1) iohexol, 2) iohexol+glucose 280 mM, 3) iohexol+NaCl 150 mM, 4) glucose 280 mM, 5) glucose 140 mM+NaCl 75 mM, 6) NaCl 150 mM. Test solutions with NaCl caused no aggregation. Test solutions without NaCl always caused macroscopic red cell aggregates. These aggregates always disappeared when saline was added to the sample. The macroscopic red cell aggregates could be dispersed to microscopic aggregates by shaking the test tubes. During the next 30 min macroscopic aggregates returned in the glucose solution but not in the iohexol solutions. In 30 min, blood mixed with iohexol solutions never coagulated while blood layered on top of the same iohexol solutions always coagulated. Blood mixed with solutions 5 and 6, both without iohexol, always coagulated. It is concluded that adding 150 mM NaCl to iohexol did not eliminate its ability to antico-agulate whole blood, but inhibited its ability to aggregate red cells. This inhibition was not caused by the osmotic effects of the added NaCl.

Influence of fibrinogen on flow properties of erythrocyte suspensions

1964 ◽  
Vol 207 (5) ◽  
pp. 1035-1040 ◽  
Author(s):  
Roe E. Wells ◽  
Thomas H. Gawronski ◽  
Paul J. Cox ◽  
Richard D. Perera
Keyword(s):  
Shear Stress ◽  
Shear Rate ◽  
Cell Aggregation ◽  
Cell Suspensions ◽  
Fibrinogen Concentration ◽  
Sedimentation Rates ◽  
Cell Aggregates ◽  
Red Cell ◽  
Flow Properties ◽  
Yield Value

The influence of fibrinogen on the flow properties of red cell suspensions (hematocrit 41) was studied by viscometry at low rates of shear (0.1–20 sec–1). These findings were correlated with sedimentation rates and photomicrographical studies of cell aggregation. Fibrinogen concentration was varied from 0.3 to 2.0 g/100 ml. The viscosity of the pure solutions of fibrinogen was independent of shear rate, ranging from 0.87 to 1.7 centipoise (cp) at 37 C. The viscosity of the cell suspensions at 10 sec–1 varied from 4.3 cp in 0.3 g/100 ml fibrinogen to 14 cp in 2 g/100 ml fibrinogen. All suspensions were markedly dependent on shear rate, viscosity increasing in exponential-like fashion as shear rate decreased. Extrapolation of plots of shear stress1/2 versus shear rate1/2 revealed the suspensions to sustain a finite stress without deformation or flow, the "yield value" increasing as fibrinogen concentration increased. Photomicrographs of dilute cell suspensions revealed the formation of cell aggregates and rouleaux, increasing in size and descent velocity as fibrinogen concentration increased.

Prevention and dispersion of contrast media induced red cell aggregates

1990 ◽  
Vol 31 (3) ◽  
pp. 309-314
Author(s):  
R. Raininko ◽  
S.-L. Ylinen
Keyword(s):  
Contrast Media ◽  
Cell Aggregates ◽  
Red Cell

The morphology of red-cell aggregates

1972 ◽  
Vol 1 (1) ◽  
pp. 47-57 ◽  
Author(s):  
Stanley Rowlands ◽  
Leona Skibo
Keyword(s):  
Cell Aggregates ◽  
Red Cell

scholarly journals Rheology and Ultrasound Scattering from Aggregated Red Cell Suspensions in Shear Flow

2004 ◽  
Vol 87 (4) ◽  
pp. 2322-2334 ◽  
Author(s):  
L. Haider ◽  
P. Snabre ◽  
M. Boynard
Keyword(s):  
Shear Flow ◽  
Cell Suspensions ◽  
Red Cell ◽  
Ultrasound Scattering
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