Envelope filtering of signals in the modulation frequency domain and evaluation of fluctuation strength

1999 ◽  
Vol 105 (2) ◽  
pp. 1102-1102
Author(s):  
Cord Walter ◽  
Reinhard Weber
2021 ◽  
Author(s):  
huseyin ozgur kazanci

Abstract Diffuse optic imaging is an important biomedical optic research tool. Diffuse optic tomography (DOT) modality needs progressive philosophical approaches for scientific contribution. Technological developments and philosophical approaches should both go forward. Phase-shift based frequency domain (FD) diffuse optical tomography (FDDOT) method was well established in the literature. The instruments were tested for brain neurofunctional imaging. A mixture of AC laser intensity and phase data were used at these works. According to those works; deep volume resolution was improved by only using phase data. Because phase data is only related to the photon mean free path in imaging tissue media. Besides this advantage, laser intensity data is also affected by noisy background light and electrical artifacts. Another most important advantage of only using phase data can be explained as time-resolved temporal change can be directly related to phase shift of modulated frequency source. At this work, the frequency domain (FD) DOT imaging method which uses phase shift data were used for simulation phantom. Laser source-driven forward model problem weight matrix simulation data was given to the simple pseudo-inverse-based inverse problem solution algorithm for one inclusion example. The inclusion image was reconstructed and demonstrated successfully. Forward model problem weight functions inside the tissue simulation media were calculated and used based on the phase shifts at the same core modulation frequency. 100 MHz modulation frequency was selected due to its FDDOT standard. 13 sources and 13 detectors were placed on the back-reflected imaging surface. 40 x, y, z cartesian coordinate grid elements were used in the image reconstruction algorithm. Photon absorption coefficient: ma = 0.1 cm-1, and scattering coefficient: ms = 100 cm-1 values were set for background simulation phantom. One inclusion object was embedded inside the imaging tissue simulation phantom background. x, y, z cartesian coordinate grid sizes were selected for 100 mm for each direction. Photon phase shift fluencies were added to the forward model problem. The forward model problem was built according to the frequency domain photon migration diffusion approximation. Forward model problem photon fluencies were calculated according to the diffusion equation approximation. The simple pseudoinverse mathematical inverse problem solution algorithm was applied to test the results. The embedded inclusion object was reconstructed successfully with the high-resolution image quality. In general, DOT techniques suffer for the low image quality, but in this work, the high-quality image was reconstructed and demonstrated. The philosophical approach has future promising DOT imaging capability. The phase shift version of the FDDOT modality has an important advantage for future purpose.


2016 ◽  
Vol 14 (1) ◽  
pp. 9-20 ◽  
Author(s):  
Sanja Aleksic ◽  
Dragana Markushev ◽  
Dragan Pantic ◽  
Mihajlo Rabasovic ◽  
Dragan Markushev ◽  
...  

The paper discusses the most common impacts of the measuring system on the amplitude and phase of the photoacoustic signals in the frequency domain using the open-cell experimental set-up. The highest signal distortions are detected at the ends of the observed modulation frequency range from 20 Hz to 20 kHz. The attenuation of the signal is observed at lower frequencies, caused by the electronic filtering of the microphone and sound card, with characteristic frequencies of 15 Hz and 25 Hz. At higher frequencies, the dominant signal distortions are caused by the microphone acoustic filtering, having characteristic frequencies around 9 kHz and 15 kHz. It has been found that the microphone incoherent noise, the so called flicker noise, is negligibly small in comparison to the signal and does not affect the signal shape. However, a coherent noise originating from the power modulation system of the light source significantly affects the shape of the signal in the range greater than 10 kHz. The effects of the coherent noise and measuring system influence are eliminated completely using the relevant signal correction procedure targeting the photoacoustic signal generated by the sample.


2021 ◽  
Author(s):  
Huseyin Ozgur Kazanci

Abstract In this study, it was illustrated that extremely high frequency (EHF) Ka-band (26.5-40 GHz) modulated frequency domain diffuse optic tomography (FDDOT) biomedical optic imaging (BOI) modality is superior to the generally accepted 100 MHz modulation frequency case. The effect of modulation frequency was shown with reconstructed images for two different modulation frequency simulation cases. Ka EHF-band frequency range covers 26.5 - 40 GHz. In this simulation study 33 GHz modulation frequency was selected. Forward model problem photon fluencies were generated for 30 equally separated sequential phase delays. Each phase delay has different photon fluence distributions inside the imaging geometry. 3.1 cm grid sizes were set in the x, y, z cartesian grid coordinate system with 31×31×31 xyz grid elements. To test the advantage of EHF-band modulation frequency, inverse problem solution algorithm was done and inclusion images were reconstructed for each modulation frequency simulation case. Original inclusion was embedded inside the imaging geometry at (15-16, 15-16, 15-16) x, y, z coordinate system in the three-dimensional (3D) cubic spatial form. Homogenous tissue background photon absorption, scattering, and anisotropy coefficients were selected as µa = 0.1 cm-1, µs = 100 cm-1, and g = 0.9. Four sources and four detectors were placed on the back-reflection geometry. Forward model problem was built between sources, voxels, and detectors. Forward model problem photon fluencies were generated based on the diffusion equation (DE) approximation of the radiative transport equation (RTE) formula in the frequency domain. Original inclusion was reconstructed by simply applying mathematical pseudoinverse problem solution function. It was observed that, reconstructed inclusion image at the 33 GHz Ka-Band modulation frequency simulation case is superior to the reconstructed inclusion image at the 100 MHz modulation frequency simulation case. Since there are too many frequency selection opportunities, the best Ka-band frequency was selected to demonstrate here. Thus, 33 GHz and 100 MHz modulation frequencies were tested against each other. These two different electronic modulation frequencies were tested and compared with each other.


Sign in / Sign up

Export Citation Format

Share Document